Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS7764 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CARTPT polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human CARTPT.
- Description
- The CART gene encodes for a protein which has an important role in the regulation of appetite and body weight. The CART (cocaine and amphetamine regulated transcript) neuropeptide is an mRNA that changes in response to psychostimulant drug administration. Injection of CART peptides into the ventral tegmental area produces psychostimulant-like effects. CART localizes to areas of the central and peripheral nervous systems and is involved in feeding behavior when injected centrally. Expression of CART in the rat hypothalamus is modulated by nutritional status, and injection of synthetic CART peptide into the forebrain ventricular system suppresses food intake, indicating a possible role in hypothalamic control of energy homeostasis. Its identification in cell bodies and central terminals of vagal afferent neurons additionally suggests a role in brainstem mechanisms of meal termination and satiety.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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