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- Product number
- 10427-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10427-2-AP, RRID:AB_2069033
- Product name
- Calnexin antibody
- Antibody type
- Polyclonal
- Description
- Calnexin antibody (Cat. #10427-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MAPK1 Mediates MAM Disruption and Mitochondrial Dysfunction in Diabetic Kidney Disease via the PACS-2-Dependent Mechanism.
Influential factors on urine EV DNA methylation detection and its diagnostic potential in prostate cancer.
Engineered nanovesicles from activated neutrophils with enriched bactericidal proteins have molecular debridement ability and promote infectious wound healing.
Adipose mesenchymal stem cell-derived exosomes promote skin wound healing in diabetic mice by regulating epidermal autophagy.
CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis.
Effect of human periodontal ligament stem cell-derived exosomes on cementoblast activity.
ANXA3-Rich Exosomes Derived from Tumor-Associated Macrophages Regulate Ferroptosis and Lymphatic Metastasis of Laryngeal Squamous Cell Carcinoma.
Exosome-mediated Delivery of miR-519e-5p Promotes Malignant Tumor Phenotype and CD8+ T-Cell Exhaustion in Metastatic PTC.
An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins.
Detection of fucosylated extracellular vesicles miR-4732-5p related to diagnosis of early lung adenocarcinoma by the electrochemical biosensor.
Low‑intensity pulsed ultrasound accelerates diabetic wound healing by ADSC‑derived exosomes via promoting the uptake of exosomes and enhancing angiogenesis.
Transcriptome sequencing of circular RNA reveals the involvement of hsa-SCMH1_0001 in the pathogenesis of Parkinson's disease.
Exosome co-delivery of a STING agonist augments immunogenicity elicited by CVB3 VP1 vaccine via promoting antigen cross-presentation of CD8 (+) DCs.
Combinatorial selective ER-phagy remodels the ER during neurogenesis.
Intracerebral fate of organic and inorganic nanoparticles is dependent on microglial extracellular vesicle function.
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
The lipid droplet protein DHRS3 is a regulator of melanoma cell state.
Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis.
Metabolic profiling in tissues and urine of patients with prostatic lesions and the diagnostic value of urine extracellular vesicles metabolites in prostate cancer.
Exosomes derived from umbilical cord mesenchymal stem cells ameliorate male infertility caused by busulfan in vivo and in vitro.
Peritumoral SPARC expression induced by exosomes from nasopharyngeal carcinoma infected Epstein-Barr virus: A poor prognostic marker.
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
ZNT5-6 and ZNT7 play an integral role in protein N-glycosylation by supplying Zn(2+) to Golgi α-mannosidase II.
Exosomal lncRNA-MIAT promotes neovascularization via the miR-133a-3p/MMP-X1 axis in diabetic retinopathy.
Engineered extracellular vesicle-based gene therapy for the treatment of discogenic back pain.
Astragaloside IV promotes exosome secretion of endothelial progenitor cells to regulate PI3KR2/SPRED1 signaling and inhibit pyroptosis of diabetic endothelial cells.
Osteoblast-derived exosomes promote osteogenic differentiation of osteosarcoma cells via URG4/Wnt signaling pathway.
Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity.
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Delphinidins from Maqui Berry (Aristotelia chilensis) ameliorate the subcellular organelle damage induced by blue light exposure in murine photoreceptor-derived cells.
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol.
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
The effects of boar seminal plasma extracellular vesicles on sperm fertility.
Adapting the endoplasmic reticulum proteostasis rescues epilepsy-associated NMDA receptor variants.
Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.
UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation.
MiR-141-3p-Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment.
Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles.
SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn(2+) homeostasis.
M2 macrophage-derived exosomal miR-26b-5p regulates macrophage polarization and chondrocyte hypertrophy by targeting TLR3 and COL10A1 to alleviate osteoarthritis.
Maternal fiber-rich diet promotes early-life intestinal development in offspring through milk-derived extracellular vesicles carrying miR-146a-5p.
OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Cerebrospinal fluid exosomal microRNAs as biomarkers for diagnosing or monitoring the progression of non-small cell lung cancer with leptomeningeal metastases.
Extracellular vesicles derived from M2-like macrophages alleviate acute lung injury in a miR-709-mediated manner.
Perilipin membrane integration determines lipid droplet heterogeneity in differentiating adipocytes.
Zinc and manganese homeostasis closely interact in mammalian cells.
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.
Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones.
Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials.
Identification of hsa-miR-619-5p and hsa-miR-4454 in plasma-derived exosomes as a potential biomarker for lung adenocarcinoma.
Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1-to-M2 transformation.
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution.
MAVI1, an endoplasmic reticulum-localized microprotein, suppresses antiviral innate immune response by targeting MAVS on mitochondrion.
Novel neutrophil extracellular trap-related mechanisms in diabetic wounds inspire a promising treatment strategy with hypoxia-challenged small extracellular vesicles.
Amelioration of ethanol-induced oxidative stress and alcoholic liver disease by in vivo RNAi targeting Cyp2e1.
Fluorescence Tracking of Small Extracellular Vesicles In Vivo.
Enhanced wound healing and hemostasis with exosome-loaded gelatin sponges from human umbilical cord mesenchymal stem cells.
FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation of ATM mRNA.
Small RNA sequencing analysis of exosomes derived from umbilical plasma in IUGR lambs.
The Exosome-Transmitted lncRNA LOC100132249 Induces Endothelial Dysfunction in Diabetic Retinopathy.
Proteomic Investigation of Differential Interactomes of Glypican 1 and a Putative Disease-Modifying Variant of Ataxia.
Lens epithelial cell-derived exosome inhibits angiogenesis in ocular pathological neovascularization through its delivery of miR-146a-5p.
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Plasma extracellular vesicle long RNAs predict response to neoadjuvant immunotherapy and survival in patients with non-small cell lung cancer.
Exosomes derived from human umbilical cord mesenchymal stem cells alleviate Parkinson's disease and neuronal damage through inhibition of microglia.
Single-cell dissection of cellular and molecular features underlying mesenchymal stem cell therapy in ischemic acute kidney injury.
PACS-2 deficiency aggravates tubular injury in diabetic kidney disease by inhibiting ER-phagy.
Urinary exosome proteins PAK6 and EGFR as noninvasive diagnostic biomarkers of diabetic nephropathy.
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy.
Manganese regulation of COPII condensation controls circulating lipid homeostasis.
CYP26B1-related disorder: expanding the ends of the spectrum through clinical and molecular evidence.
Prognostic and immunological role of cancer-associated fibroblasts-derived exosomal protein in esophageal squamous cell carcinoma.
Heterozygous variants c.781G>A and c.1066dup of serine protease 56 cause familial nanophthalmos by impairing serine-type endopeptidase activity.
Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins.
Extracellular Vesicles and Their Renin-Angiotensin Cargo as a Link between Metabolic Syndrome and Parkinson's Disease.
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
Lymphocyte migration regulation related proteins in urine exosomes may serve as a potential biomarker for lung cancer diagnosis.
PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation.
ASTER-B regulates mitochondrial carotenoid transport and homeostasis.
Mesenchymal stem cells ameliorate cisplatin-induced acute kidney injury via let-7b-5p.
Plasma exosome-derived circGAPVD1 as a potential diagnostic marker for colorectal cancer.
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair.
Testicular exosomes disturb the immunosuppressive phenotype of testicular macrophages mediated by miR-155-5p in uropathogenic Escherichia coli-induced orchitis.
ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Extracellular vesicle-mediated delivery of anti-miR-106b inhibits morphine-induced primary ciliogenesis in the brain.
Stress Granules Inhibit Coxsackievirus B3-Mediated Cell Death via Reduction of Mitochondrial Reactive Oxygen Species and Viral Extracellular Release.
CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation.
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Extracellular Vesicles Released from Macrophages Infected with Mycoplasma pneumoniae Stimulate Proinflammatory Response via the TLR2-NF-κB/JNK Signaling Pathway.
SERS spectroscopy with machine learning to analyze human plasma derived sEVs for coronary artery disease diagnosis and prognosis.
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Proteomic Characterization of Peritoneal Extracellular Vesicles in a Mouse Model of Peritoneal Fibrosis.
p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.
Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps.
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Exosomal microRNA‑4516, microRNA‑203 and SFRP1 are potential biomarkers of acute myocardial infarction.
Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction.
miR-142-3p encapsulated in T lymphocyte-derived tissue small extracellular vesicles induces Treg function defect and thyrocyte destruction in Hashimoto's thyroiditis.
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
TMEM41B Is an Interferon-Stimulated Gene That Promotes Pseudorabies Virus Replication.
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies.
Extracellular vesicle-packaged ILK from mesothelial cells promotes fibroblast activation in peritoneal fibrosis.
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Two microRNAs of plasma-derived small extracellular vesicles as biomarkers for metastatic non-small cell lung cancer.
Changes in urinary exosomal protein CALM1 may serve as an early noninvasive biomarker for diagnosing diabetic kidney disease.
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Low-intensity pulsed ultrasound (LIPUS) enhances the anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles.
miR-150-5p in neutrophil-derived extracellular vesicles associated with sepsis-induced cardiomyopathy in septic patients.
A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma.
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
Mesenchymal stem cells-derived exosomes ameliorate high glucose and lipopolysaccharide-induced HPMECs injury through the Nrf2/HO-1 pathway.
Integrated transcriptomics, proteomics, and functional analysis to characterize the tissue-specific small extracellular vesicle network of breast cancer.
Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.
SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum.
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization.
Extracellular vesicles long RNA profiling identifies abundant mRNA, circRNA and lncRNA in human bile as potential biomarkers for cancer diagnosis.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
MiR-146b-5p enriched bioinspired exosomes derived from fucoidan-directed induction mesenchymal stem cells protect chondrocytes in osteoarthritis by targeting TRAF6.
Cultured lymphocytes' mitochondrial genome integrity is not altered by cladribine.
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease.
The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity.
Tumor-Associated Extracellular Microvesicles with Fluorine-Modified Carbohydrate Antigens Trigger a Stronger Antitumor Immune Response.
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling.
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
MicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacy.
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
Pigmentation and TYRP1 expression are mediated by zinc through the early secretory pathway-resident ZNT proteins.
Phenylethanoid glycosides extract from Cistanche deserticola ameliorates atherosclerosis in apolipoprotein E-deficient mice and regulates intestinal PPARγ-LXRα-ABCA1 pathway.
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Signal-Retaining Autophagy Indicator as a Quantitative Imaging Method for ER-Phagy.
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
miR-29a-3p in Exosomes from Heme Oxygenase-1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia-Reperfusion Injury in Rats by Suppressing Ferroptosis via Iron Responsive Element Binding Protein 2.
Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation.
The potential role of exosomal miRNAs and membrane proteins in acute HIV-infected people.
Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain.
Characterization and subcellular localization of Alongshan virus proteins.
Exosomal CD44 Transmits Lymph Node Metastatic Capacity Between Gastric Cancer Cells via YAP-CPT1A-Mediated FAO Reprogramming.
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Hypoxic Cell-Derived Extracellular Vesicles Aggravate Rectal Injury Following Radiotherapy via MiR-122-5p.
The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formation.
Phospholipid peroxidation inhibits autophagy via stimulating the delipidation of oxidized LC3-PE.
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
De novo sphingolipid biosynthesis necessitates detoxification in cancer cells.
TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.
TMEΜ45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication.
TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia.
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.
The role of hepatic Surf4 in lipoprotein metabolism and the development of atherosclerosis in apoE(-/-) mice.
The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 pathway following hypoxia-ischemia in neonatal mice.
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Mutated lncRNA increase the risk of type 2 diabetes by promoting β cell dysfunction and insulin resistance.
Extracellular vesicles derived from endometrial epithelial cells deliver exogenous miR-92b-3p to affect the function of embryonic trophoblast cells via targeting TSC1 and DKK3.
Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy.
Proteomic and miRNA Profiles of Exosomes Derived from Myometrial Tissue in Laboring Women.
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection.
Extracellular vesicles from human urine-derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration.
Plasma Extracellular Vesicle Long RNA in Diagnosis and Prediction in Small Cell Lung Cancer.
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1.
Extracellular vesicle-derived long non-coding RNA as circulating biomarkers for endometriosis.
The endoplasmic reticulum adopts two distinct tubule forms.
Autophagic LC3(+) calcified extracellular vesicles initiate cartilage calcification in osteoarthritis.
Evaluation of plasma exosomal miRNAs as potential diagnostic biomarkers of lymph node metastasis in papillary thyroid carcinoma.
Photobiomodulation promotes hair regeneration in injured skin by enhancing migration and exosome secretion of dermal papilla cells.
ESCRT dysfunction compromises endoplasmic reticulum maturation and autophagosome biogenesis in Drosophila.
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
N-terminome analyses underscore the prevalence of SPPL3-mediated intramembrane proteolysis among Golgi-resident enzymes and its role in Golgi enzyme secretion.
MOSPD2 is an endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis.
Preparation of Recombinant Human Collagen III Protein Hydrogels with Sustained Release of Extracellular Vesicles for Skin Wound Healing.
Micro-RNAs from Plasma-Derived Small Extracellular Vesicles as Potential Biomarkers for Tic Disorders Diagnosis.
Exosomal tRF-Leu-AAG-001 derived from mast cell as a potential non-invasive diagnostic biomarker for endometriosis.
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.
FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia.
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice.
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease.
Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p.
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication.
Plasma extracellular vesicle microRNA profiling and the identification of a diagnostic signature for stage I lung adenocarcinoma.
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
Atrophic skeletal muscle fibre-derived small extracellular vesicle miR-690 inhibits satellite cell differentiation during ageing.
Identification of Circulating Exosomal microRNAs Associated with Radioiodine Refractory in Papillary Thyroid Carcinoma.
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Exosomes from the Uterine Cavity Mediate Immune Dysregulation via Inhibiting the JNK Signal Pathway in Endometriosis.
A cryostat-based frozen section method to increase the yield of extracellular vesicles extracted from different tissues.
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency.
Differential proteomic analysis of plasma-derived exosomes as diagnostic biomarkers for chronic HBV-related liver disease.
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.
Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration.
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Identification of the Association Between Toll-Like Receptors and T-Cell Activation in Takayasu's Arteritis.
GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity.
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Neuronal Exosomes Secreted under Oxygen-Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth.
Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence.
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation.
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Hypercholesterolemia risk associated Abca6 does not regulate lipoprotein metabolism in mice or hamster.
Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.
hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression.
AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins.
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι.
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation.
Identification of exosome miRNAs in bronchial epithelial cells after PM2.5 chronic exposure.
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Secretome of Activated Fibroblasts Induced by Exosomes for the Discovery of Biomarkers in Non-Small Cell Lung Cancer.
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Small RNA-seq analysis of extracellular vesicles from porcine uterine flushing fluids during peri-implantation.
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease.
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Japanese encephalitis virus manipulates lysosomes membrane for RNA replication and utilizes autophagy components for intracellular growth.
Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma.
STING regulates BCR signaling in normal and malignant B cells.
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Extracellular-vesicle containing miRNA-503-5p released by macrophages contributes to atherosclerosis.
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage.
Mechanism of Sanguinarine in Inhibiting Macrophages to Promote Metastasis and Proliferation of Lung Cancer via Modulating the Exosomes in A549 Cells.
Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance.
Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer.
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Insight into the proteomic profiling of exosomes secreted by human OM-MSCs reveals a new potential therapy.
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8(+) T cell response in tumor.
Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer.
HPV + HNSCC-derived exosomal miR-9 induces macrophage M1 polarization and increases tumor radiosensitivity.
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice.
APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin.
Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling.
The protective effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on cisplatin-damaged granulosa cells.
Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSCs) enhances Nanog expression and provides a serum-free condition for exosome isolation.
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
Polyethylene Glycol 35 (PEG35) Modulates Exosomal Uptake and Function.
Mycobacterium tuberculosis MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response.
SCYL1 arginine methylation by PRMT1 is essential for neurite outgrowth via Golgi morphogenesis.
USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy.
Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress.
Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2.
Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation.
Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.
Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress.
Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway.
Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia.
Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection.
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Two novel ANK1 loss-of-function mutations in Chinese families with hereditary spherocytosis.
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression.
Microglia as modulators of exosomal alpha-synuclein transmission.
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway.
Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways.
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.
In Vivo Tracking of Multiple Tumor Exosomes Labeled by Phospholipid-Based Bioorthogonal Conjugation.
Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.
A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation.
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Protein kinase D at the Golgi controls NLRP3 inflammasome activation.
Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis.
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.
DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector.
Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer.
Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.
Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.
IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
PolyC-binding protein 1 interacts with 5'-untranslated region of enterovirus 71 RNA in membrane-associated complex to facilitate viral replication.
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Rab18 and a Rab18 GEF complex are required for normal ER structure.
Reduced expression of members of the mhc-i antigen processing machinery in ethnic Uighur women with cervical cancer in the Xinjiang region of China.
ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.
Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis.
Liu S, Han S, Wang C, Chen H, Xu Q, Feng S, Wang Y, Yao J, Zhou Q, Tang X, Lin L, Hu L, Davidson AJ, Yang B, Ye C, Yang F, Mao J, Tong C, Chen J, Jiang H
International journal of biological sciences 2024;20(2):569-584
International journal of biological sciences 2024;20(2):569-584
Influential factors on urine EV DNA methylation detection and its diagnostic potential in prostate cancer.
Ding T, Diao Y, Zeng X, Zhou L, Wu G, Liu J, Hao X
Frontiers in genetics 2024;15:1338468
Frontiers in genetics 2024;15:1338468
Engineered nanovesicles from activated neutrophils with enriched bactericidal proteins have molecular debridement ability and promote infectious wound healing.
Jin H, Wen X, Sun R, Yu Y, Guo Z, Yang Y, Li L, Sun B
Burns & trauma 2024;12:tkae018
Burns & trauma 2024;12:tkae018
Adipose mesenchymal stem cell-derived exosomes promote skin wound healing in diabetic mice by regulating epidermal autophagy.
Ren H, Su P, Zhao F, Zhang Q, Huang X, He C, Wu Q, Wang Z, Ma J, Wang Z
Burns & trauma 2024;12:tkae001
Burns & trauma 2024;12:tkae001
CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis.
Peng X, Chen X, Peng S, Chen Y, Li Y, Tian Y
Molecular biotechnology 2024 Sep;66(9):2381-2395
Molecular biotechnology 2024 Sep;66(9):2381-2395
Effect of human periodontal ligament stem cell-derived exosomes on cementoblast activity.
Li S, Guan X, Yu W, Zhao Z, Sun Y, Bai Y
Oral diseases 2024 May;30(4):2511-2522
Oral diseases 2024 May;30(4):2511-2522
ANXA3-Rich Exosomes Derived from Tumor-Associated Macrophages Regulate Ferroptosis and Lymphatic Metastasis of Laryngeal Squamous Cell Carcinoma.
Xu L, Li W, Liu D, Cao J, Ge J, Liu X, Wang Y, Teng Y, Liu P, Guo X, He C, Liu M, Tian L
Cancer immunology research 2024 May 2;12(5):614-630
Cancer immunology research 2024 May 2;12(5):614-630
Exosome-mediated Delivery of miR-519e-5p Promotes Malignant Tumor Phenotype and CD8+ T-Cell Exhaustion in Metastatic PTC.
Li G, Chen W, Jiang K, Huang J, Zhong J, Liu X, Wei T, Gong R, Li Z, Zhu J, Shi H, Lei J
The Journal of clinical endocrinology and metabolism 2024 May 17;109(6):1601-1617
The Journal of clinical endocrinology and metabolism 2024 May 17;109(6):1601-1617
An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins.
Ji J, Cui MK, Zou R, Wu MZ, Ge MX, Li J, Zhang ZR
Molecular cell 2024 May 16;84(10):1917-1931.e15
Molecular cell 2024 May 16;84(10):1917-1931.e15
Detection of fucosylated extracellular vesicles miR-4732-5p related to diagnosis of early lung adenocarcinoma by the electrochemical biosensor.
Zhu S, Chen J, Yu L, Li J, You S, Zheng Y, Zhuang W, Qiu B, Huang Y
Scientific reports 2024 May 16;14(1):11217
Scientific reports 2024 May 16;14(1):11217
Low‑intensity pulsed ultrasound accelerates diabetic wound healing by ADSC‑derived exosomes via promoting the uptake of exosomes and enhancing angiogenesis.
Zhong F, Cao S, Yang L, Liu J, Gui B, Wang H, Jiang N, Zhou Q, Deng Q
International journal of molecular medicine 2024 Mar;53(3)
International journal of molecular medicine 2024 Mar;53(3)
Transcriptome sequencing of circular RNA reveals the involvement of hsa-SCMH1_0001 in the pathogenesis of Parkinson's disease.
Wang Q, Wang H, Zhao X, Han C, Liu C, Li Z, Du T, Sui Y, Zhang X, Zhang J, Xiao Y, Cai G, Meng F
CNS neuroscience & therapeutics 2024 Mar;30(3):e14435
CNS neuroscience & therapeutics 2024 Mar;30(3):e14435
Exosome co-delivery of a STING agonist augments immunogenicity elicited by CVB3 VP1 vaccine via promoting antigen cross-presentation of CD8 (+) DCs.
Zhang C, Cao Q, Li Y, Lu J, Xiong S, Yue Y
International journal of biological macromolecules 2024 Mar;261(Pt 1):129518
International journal of biological macromolecules 2024 Mar;261(Pt 1):129518
Combinatorial selective ER-phagy remodels the ER during neurogenesis.
Hoyer MJ, Capitanio C, Smith IR, Paoli JC, Bieber A, Jiang Y, Paulo JA, Gonzalez-Lozano MA, Baumeister W, Wilfling F, Schulman BA, Harper JW
Nature cell biology 2024 Mar;26(3):378-392
Nature cell biology 2024 Mar;26(3):378-392
Intracerebral fate of organic and inorganic nanoparticles is dependent on microglial extracellular vesicle function.
Gao J, Song Q, Gu X, Jiang G, Huang J, Tang Y, Yu R, Wang A, Huang Y, Zheng G, Chen H, Gao X
Nature nanotechnology 2024 Mar;19(3):376-386
Nature nanotechnology 2024 Mar;19(3):376-386
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
Zheng N, Liu S, Chen J, Xu Y, Cao W, Lin J, Lu G, Zhang G
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
The lipid droplet protein DHRS3 is a regulator of melanoma cell state.
Johns E, Ma Y, Louphrasitthipol P, Peralta C, Hunter MV, Raymond JH, Molina H, Goding CR, White RM
bioRxiv : the preprint server for biology 2024 Mar 28;
bioRxiv : the preprint server for biology 2024 Mar 28;
Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis.
Chen G, Li X, Zhou X, Li Y, Yu H, Peng X, Bai X, Zhang C, Feng Z, Mei Y, Li L, Liu Y, Gou X, Jiang Y
Scientific reports 2024 Mar 20;14(1):6720
Scientific reports 2024 Mar 20;14(1):6720
Metabolic profiling in tissues and urine of patients with prostatic lesions and the diagnostic value of urine extracellular vesicles metabolites in prostate cancer.
Ding T, He W, Yan H, Wei Z, Zeng X, Hao X
Clinica chimica acta; international journal of clinical chemistry 2024 Mar 15;556:117845
Clinica chimica acta; international journal of clinical chemistry 2024 Mar 15;556:117845
Exosomes derived from umbilical cord mesenchymal stem cells ameliorate male infertility caused by busulfan in vivo and in vitro.
Yue D, Wang F, Han Y, Xiong C, Yang R
Ecotoxicology and environmental safety 2024 Mar 1;272:116063
Ecotoxicology and environmental safety 2024 Mar 1;272:116063
Peritumoral SPARC expression induced by exosomes from nasopharyngeal carcinoma infected Epstein-Barr virus: A poor prognostic marker.
Dochi H, Kondo S, Komura S, Moriyama-Kita M, Komori T, Nanbo A, Sakaguchi M, Fukuyo M, Hamabe-Horiike T, Tanaka M, Mizokami H, Kano M, Kitagawa Y, Kobayashi E, Hirai N, Ueno T, Nakanishi Y, Endo K, Sugimoto H, Hanayama R, Kaneda A, Yoshizaki T
International journal of cancer 2024 Mar 1;154(5):895-911
International journal of cancer 2024 Mar 1;154(5):895-911
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Ma W, Wu D, Long C, Liu J, Xu L, Zhou L, Dou Q, Ge Y, Zhou C, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
ZNT5-6 and ZNT7 play an integral role in protein N-glycosylation by supplying Zn(2+) to Golgi α-mannosidase II.
Yuasa H, Morino N, Wagatsuma T, Munekane M, Ueda S, Matsunaga M, Uchida Y, Katayama T, Katoh T, Kambe T
The Journal of biological chemistry 2024 Jun;300(6):107378
The Journal of biological chemistry 2024 Jun;300(6):107378
Exosomal lncRNA-MIAT promotes neovascularization via the miR-133a-3p/MMP-X1 axis in diabetic retinopathy.
Li X, Cao Q, Xu C, Wang J, Pan T, Liu Q, Xie P, Hu Z
Experimental eye research 2024 Jun;243:109912
Experimental eye research 2024 Jun;243:109912
Engineered extracellular vesicle-based gene therapy for the treatment of discogenic back pain.
Tang SN, Salazar-Puerta AI, Heimann MK, Kuchynsky K, Rincon-Benavides MA, Kordowski M, Gunsch G, Bodine L, Diop K, Gantt C, Khan S, Bratasz A, Kokiko-Cochran O, Fitzgerald J, Laudier DM, Hoyland JA, Walter BA, Higuita-Castro N, Purmessur D
Biomaterials 2024 Jul;308:122562
Biomaterials 2024 Jul;308:122562
Astragaloside IV promotes exosome secretion of endothelial progenitor cells to regulate PI3KR2/SPRED1 signaling and inhibit pyroptosis of diabetic endothelial cells.
Xiong W, Zhang X, Zhou J, Chen J, Liu Y, Yan Y, Tan M, Huang H, Si Y, Wei Y
Cytotherapy 2024 Jan;26(1):36-50
Cytotherapy 2024 Jan;26(1):36-50
Osteoblast-derived exosomes promote osteogenic differentiation of osteosarcoma cells via URG4/Wnt signaling pathway.
Leng Y, Li J, Long Z, Li C, Zhang L, Huang Z, Xi J, Liu Y
Bone 2024 Jan;178:116933
Bone 2024 Jan;178:116933
Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity.
Zou Y, Xiao W, Liu D, Li X, Li L, Peng L, Xiong Y, Gan H, Ren X
Immunity, inflammation and disease 2024 Jan;12(1):e1139
Immunity, inflammation and disease 2024 Jan;12(1):e1139
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Wang W, Ren X, Chen X, Hong Q, Cai G
JCI insight 2024 Jan 23;9(2)
JCI insight 2024 Jan 23;9(2)
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Jia C, Xiang Z, Zhang P, Liu L, Zhu X, Yu R, Liu Z, Wang S, Liu K, Wang Z, Vasilev K, Zhou S, Geng Z, Liu X, Zhao Y, Gao Y, Cheng L, Li Y
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Delphinidins from Maqui Berry (Aristotelia chilensis) ameliorate the subcellular organelle damage induced by blue light exposure in murine photoreceptor-derived cells.
Yamazaki K, Ishida K, Otsu W, Muramatsu A, Nakamura S, Yamada W, Tsusaki H, Shimoda H, Hara H, Shimazawa M
BMC complementary medicine and therapies 2024 Jan 2;24(1):3
BMC complementary medicine and therapies 2024 Jan 2;24(1):3
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Tao H, Song SJ, Fan ZW, Li WT, Jin X, Jiang W, Bai J, Shi ZZ
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol.
Kemmoku H, Takahashi K, Mukai K, Mori T, Hirosawa KM, Kiku F, Uchida Y, Kuchitsu Y, Nishioka Y, Sawa M, Kishimoto T, Tanaka K, Yokota Y, Arai H, Suzuki KGN, Taguchi T
Nature communications 2024 Jan 11;15(1):220
Nature communications 2024 Jan 11;15(1):220
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
Zhang R, Chen X, Miao C, Chen Y, Li Y, Shen J, Yuan M, Chen M, Cheng J, Liu S, Sun Q, Wu J
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
The effects of boar seminal plasma extracellular vesicles on sperm fertility.
Xu Z, Xie Y, Wu C, Gu T, Zhang X, Yang J, Yang H, Zheng E, Huang S, Xu Z, Li Z, Cai G, Liu D, Hong L, Wu Z
Theriogenology 2024 Jan 1;213:79-89
Theriogenology 2024 Jan 1;213:79-89
Adapting the endoplasmic reticulum proteostasis rescues epilepsy-associated NMDA receptor variants.
Zhang PP, Benske TM, Ahn LY, Schaffer AE, Paton JC, Paton AW, Mu TW, Wang YJ
Acta pharmacologica Sinica 2024 Feb;45(2):282-297
Acta pharmacologica Sinica 2024 Feb;45(2):282-297
Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.
Zhang W, Zhang Z, Xiang Y, Gu DD, Chen J, Chen Y, Zhai S, Liu Y, Jiang T, Liu C, He B, Yan M, Wang Z, Xu J, Cao YL, Deng B, Zeng D, Lei J, Zhuo J, Lei X, Long Z, Jin B, Chen T, Li D, Shen Y, Hu J, Gao S, Liu Q
Nature structural & molecular biology 2024 Feb;31(2):219-231
Nature structural & molecular biology 2024 Feb;31(2):219-231
UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation.
Ahlstedt BA, Ganji R, Mukkavalli S, Paulo JA, Gygi SP, Raman M
EMBO reports 2024 Feb;25(2):672-703
EMBO reports 2024 Feb;25(2):672-703
MiR-141-3p-Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment.
Meng S, Wei Q, Chen S, Liu X, Cui S, Huang Q, Chu Z, Ma K, Zhang W, Hu W, Li S, Wang Z, Tian L, Zhao Z, Li H, Fu X, Zhang C
Small (Weinheim an der Bergstrasse, Germany) 2024 Feb;20(8):e2305374
Small (Weinheim an der Bergstrasse, Germany) 2024 Feb;20(8):e2305374
Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles.
Lu W, Yan J, Wang C, Qin W, Han X, Qin Z, Wei Y, Xu H, Gao J, Gao C, Ye T, Tay FR, Niu L, Jiao K
Bone research 2024 Feb 22;12(1):11
Bone research 2024 Feb 22;12(1):11
SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn(2+) homeostasis.
Song Y, Geng W, Zhu D, Liang H, Du Z, Tong B, Wang K, Li S, Gao Y, Feng X, Liao Z, Mei R, Yang C
Free radical biology & medicine 2024 Feb 20;212:220-233
Free radical biology & medicine 2024 Feb 20;212:220-233
M2 macrophage-derived exosomal miR-26b-5p regulates macrophage polarization and chondrocyte hypertrophy by targeting TLR3 and COL10A1 to alleviate osteoarthritis.
Qian Y, Chu G, Zhang L, Wu Z, Wang Q, Guo JJ, Zhou F
Journal of nanobiotechnology 2024 Feb 19;22(1):72
Journal of nanobiotechnology 2024 Feb 19;22(1):72
Maternal fiber-rich diet promotes early-life intestinal development in offspring through milk-derived extracellular vesicles carrying miR-146a-5p.
Lu D, Liu Y, Kang L, Zhang X, Hu J, Ye H, Huang B, Wu Y, Zhao J, Dai Z, Wang J, Han D
Journal of nanobiotechnology 2024 Feb 16;22(1):65
Journal of nanobiotechnology 2024 Feb 16;22(1):65
OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.
Ma W, Sun Y, Yan R, Zhang P, Shen S, Lu H, Zhou Z, Jiang Z, Ye L, Mao Q, Xiong N, Jia W, Sun L, Gao P, Zhang H
Molecular cell 2024 Feb 1;84(3):538-551.e7
Molecular cell 2024 Feb 1;84(3):538-551.e7
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Zhao JL, Zhao L, Zhan QN, Liu M, Zhang T, Chu WW
Current medical science 2024 Apr;44(2):333-345
Current medical science 2024 Apr;44(2):333-345
Cerebrospinal fluid exosomal microRNAs as biomarkers for diagnosing or monitoring the progression of non-small cell lung cancer with leptomeningeal metastases.
Li H, Xia M, Zheng S, Lin Y, Yu T, Xie Y, Shen Y, Liu X, Qian X, Yin Z
Biotechnology & genetic engineering reviews 2024 Apr;40(1):359-380
Biotechnology & genetic engineering reviews 2024 Apr;40(1):359-380
Extracellular vesicles derived from M2-like macrophages alleviate acute lung injury in a miR-709-mediated manner.
Yang J, Huang X, Yu Q, Wang S, Wen X, Bai S, Cao L, Zhang K, Zhang S, Wang X, Chen Z, Cai Z, Zhang G
Journal of extracellular vesicles 2024 Apr;13(4):e12437
Journal of extracellular vesicles 2024 Apr;13(4):e12437
Perilipin membrane integration determines lipid droplet heterogeneity in differentiating adipocytes.
Majchrzak M, Stojanović O, Ajjaji D, Ben M'barek K, Omrane M, Thiam AR, Klemm RW
Cell reports 2024 Apr 23;43(4):114093
Cell reports 2024 Apr 23;43(4):114093
Zinc and manganese homeostasis closely interact in mammalian cells.
Nishito Y, Kamimura Y, Nagamatsu S, Yamamoto N, Yasui H, Kambe T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23605
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23605
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.
Zhang Q, Shen X, Yuan X, Huang J, Zhu Y, Zhu T, Zhang T, Wu H, Wu Q, Fan Y, Ni J, Meng L, He A, Shi C, Li H, Hu Q, Wang J, Chang C, Huang F, Li F, Chen M, Liu A, Ye S, Zheng M, Fang H
Nature communications 2024 Apr 13;15(1):3213
Nature communications 2024 Apr 13;15(1):3213
Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
Fang XX, Wei P, Zhao K, Sheng ZC, Song BL, Yin L, Luo J
The Journal of cell biology 2024 Apr 1;223(4)
The Journal of cell biology 2024 Apr 1;223(4)
Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.
Arab M, Nayak SC, Vitali T, Lowe M
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones.
Tao S, Yang EJ, Zong G, Mou PK, Ren G, Pu Y, Chen L, Kwon HJ, Zhou J, Hu Z, Khosravi A, Zhang Q, Du Y, Shi WQ, Shim JS
International journal of biological sciences 2023;19(13):4020-4035
International journal of biological sciences 2023;19(13):4020-4035
Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials.
Wang X, Hu S, Zhu D, Li J, Cheng K, Liu G
Nano research 2023;16(5):7248-7259
Nano research 2023;16(5):7248-7259
Identification of hsa-miR-619-5p and hsa-miR-4454 in plasma-derived exosomes as a potential biomarker for lung adenocarcinoma.
Feng L, Feng Z, Hu J, Gao J, Li A, He X, Liu L, Shen Z
Frontiers in genetics 2023;14:1138230
Frontiers in genetics 2023;14:1138230
Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1-to-M2 transformation.
Zhang C, Liao W, Li W, Li M, Xu X, Sun H, Xue Y, Liu L, Qiu J, Zhang C, Zhang X, Ye J, Du J, Deng DYB, Deng W, Li T
Frontiers in physiology 2023;14:1131701
Frontiers in physiology 2023;14:1131701
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution.
Chai C, Sui K, Tang J, Yu H, Yang C, Zhang H, Li SC, Zhong JF, Wang Z, Zhang X
Theranostics 2023;13(12):3943-3963
Theranostics 2023;13(12):3943-3963
MAVI1, an endoplasmic reticulum-localized microprotein, suppresses antiviral innate immune response by targeting MAVS on mitochondrion.
Shi TT, Huang Y, Li Y, Dai XL, He YH, Ding JC, Ran T, Shi Y, Yuan Q, Li WJ, Liu W
Science advances 2023 Sep;9(35):eadg7053
Science advances 2023 Sep;9(35):eadg7053
Novel neutrophil extracellular trap-related mechanisms in diabetic wounds inspire a promising treatment strategy with hypoxia-challenged small extracellular vesicles.
Chu Z, Huang Q, Ma K, Liu X, Zhang W, Cui S, Wei Q, Gao H, Hu W, Wang Z, Meng S, Tian L, Li H, Fu X, Zhang C
Bioactive materials 2023 Sep;27:257-270
Bioactive materials 2023 Sep;27:257-270
Amelioration of ethanol-induced oxidative stress and alcoholic liver disease by in vivo RNAi targeting Cyp2e1.
Wang Y, Chen Q, Wu S, Sun X, Yin R, Ouyang Z, Yin H, Wei Y
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3906-3918
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3906-3918
Fluorescence Tracking of Small Extracellular Vesicles In Vivo.
Chen Y, Shi Y, Tao Z
Pharmaceutics 2023 Sep 8;15(9)
Pharmaceutics 2023 Sep 8;15(9)
Enhanced wound healing and hemostasis with exosome-loaded gelatin sponges from human umbilical cord mesenchymal stem cells.
Hu XM, Wang CC, Xiao Y, Jiang P, Liu Y, Qi ZQ
World journal of stem cells 2023 Sep 26;15(9):947-959
World journal of stem cells 2023 Sep 26;15(9):947-959
FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation of ATM mRNA.
Geng Y, Long X, Zhang Y, Wang Y, You G, Guo W, Zhuang G, Zhang Y, Cheng X, Yuan Z, Zan J
Journal of translational medicine 2023 Sep 22;21(1):652
Journal of translational medicine 2023 Sep 22;21(1):652
Small RNA sequencing analysis of exosomes derived from umbilical plasma in IUGR lambs.
Lu J, Li H, Zheng X, Liu Y, Zhao P
Communications biology 2023 Sep 15;6(1):943
Communications biology 2023 Sep 15;6(1):943
The Exosome-Transmitted lncRNA LOC100132249 Induces Endothelial Dysfunction in Diabetic Retinopathy.
Hu Z, Wang J, Pan T, Li X, Tao C, Wu Y, Wang X, Zhang Z, Liu Y, Zhang W, Xu C, Wu X, Gu Q, Fan Y, Qian H, Mugisha A, Yuan S, Liu Q, Xie P
Diabetes 2023 Sep 1;72(9):1307-1319
Diabetes 2023 Sep 1;72(9):1307-1319
Proteomic Investigation of Differential Interactomes of Glypican 1 and a Putative Disease-Modifying Variant of Ataxia.
Cengiz Winter N, Karakaya M, Mosen P, Brusius I, Anlar B, Haliloglu G, Winter D, Wirth B
Journal of proteome research 2023 Sep 1;22(9):3081-3095
Journal of proteome research 2023 Sep 1;22(9):3081-3095
Lens epithelial cell-derived exosome inhibits angiogenesis in ocular pathological neovascularization through its delivery of miR-146a-5p.
Pan T, Wu Y, Zhang X, Wang J, Wang X, Gu Q, Xu C, Fan Y, Li X, Xie P, Liu Q, Hu Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23192
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23192
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Zhang Y, Peng X, Xue M, Liu J, Shang G, Jiang M, Chen D, Liu B, Wang Y, Jia X, Xu J, Zhang F, Hu Y
Biogerontology 2023 Oct;24(5):813-827
Biogerontology 2023 Oct;24(5):813-827
Plasma extracellular vesicle long RNAs predict response to neoadjuvant immunotherapy and survival in patients with non-small cell lung cancer.
Guo W, Zhou B, Zhao L, Huai Q, Tan F, Xue Q, Lv F, Gao S, He J
Pharmacological research 2023 Oct;196:106921
Pharmacological research 2023 Oct;196:106921
Exosomes derived from human umbilical cord mesenchymal stem cells alleviate Parkinson's disease and neuronal damage through inhibition of microglia.
Zhang ZX, Zhou YJ, Gu P, Zhao W, Chen HX, Wu RY, Zhou LY, Cui QZ, Sun SK, Zhang LQ, Zhang K, Xu HJ, Chai XQ, An SJ
Neural regeneration research 2023 Oct;18(10):2291-2300
Neural regeneration research 2023 Oct;18(10):2291-2300
Single-cell dissection of cellular and molecular features underlying mesenchymal stem cell therapy in ischemic acute kidney injury.
Wang W, Zhang M, Ren X, Song Y, Xu Y, Zhuang K, Xiao T, Guo X, Wang S, Hong Q, Feng Z, Chen X, Cai G
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Oct 4;31(10):3067-3083
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Oct 4;31(10):3067-3083
PACS-2 deficiency aggravates tubular injury in diabetic kidney disease by inhibiting ER-phagy.
Yang J, Li L, Li C, Chen W, Liu Y, Luo S, Zhao C, Han Y, Yang M, Zhao H, Jiang N, Xi Y, Tang C, Cai J, Xiao L, Liu H, Sun L
Cell death & disease 2023 Oct 4;14(10):649
Cell death & disease 2023 Oct 4;14(10):649
Urinary exosome proteins PAK6 and EGFR as noninvasive diagnostic biomarkers of diabetic nephropathy.
Li T, Liu TC, Liu N, Li MJ, Zhang M
BMC nephrology 2023 Oct 3;24(1):291
BMC nephrology 2023 Oct 3;24(1):291
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy.
Sun Y, Zheng H, Qian L, Liu Y, Zhu D, Xu Z, Chang W, Xu J, Wang L, Sun B, Gu L, Yuan H, Lou H
JACS Au 2023 Oct 23;3(10):2749-2762
JACS Au 2023 Oct 23;3(10):2749-2762
Manganese regulation of COPII condensation controls circulating lipid homeostasis.
Wang X, Huang R, Wang Y, Zhou W, Hu Y, Yao Y, Cheng K, Li X, Xu B, Zhang J, Xu Y, Zeng F, Zhu Y, Chen XW
Nature cell biology 2023 Nov;25(11):1650-1663
Nature cell biology 2023 Nov;25(11):1650-1663
CYP26B1-related disorder: expanding the ends of the spectrum through clinical and molecular evidence.
Silveira KC, Fonseca IC, Oborn C, Wengryn P, Ghafoor S, Beke A, Dreseris ES, Wong C, Iacovone A, Soltys CL, Babul-Hirji R, Artigalas O, Antolini-Tavares A, Gingras AC, Campos E, Cavalcanti DP, Kannu P
Human genetics 2023 Nov;142(11):1571-1586
Human genetics 2023 Nov;142(11):1571-1586
Prognostic and immunological role of cancer-associated fibroblasts-derived exosomal protein in esophageal squamous cell carcinoma.
Wang Z, Zhang M, Liu L, Yang Y, Qiu J, Yu Y, Li J
International immunopharmacology 2023 Nov;124(Pt A):110837
International immunopharmacology 2023 Nov;124(Pt A):110837
Heterozygous variants c.781G>A and c.1066dup of serine protease 56 cause familial nanophthalmos by impairing serine-type endopeptidase activity.
Wu W, Xu J, Yin H, Fu C, Yao K, Chen X
The British journal of ophthalmology 2023 Nov;107(11):1750-1756
The British journal of ophthalmology 2023 Nov;107(11):1750-1756
Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins.
Page KR, Nguyen VN, Pleiner T, Tomaleri GP, Wang ML, Guna A, Wang TY, Chou TF, Voorhees RM
bioRxiv : the preprint server for biology 2023 Nov 29;
bioRxiv : the preprint server for biology 2023 Nov 29;
Extracellular Vesicles and Their Renin-Angiotensin Cargo as a Link between Metabolic Syndrome and Parkinson's Disease.
Pedrosa MA, Labandeira CM, Lago-Baameiro N, Valenzuela R, Pardo M, Labandeira-Garcia JL, Rodriguez-Perez AI
Antioxidants (Basel, Switzerland) 2023 Nov 26;12(12)
Antioxidants (Basel, Switzerland) 2023 Nov 26;12(12)
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
Serwach K, Nurowska E, Klukowska M, Zablocka B, Gruszczynska-Biegala J
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
Lymphocyte migration regulation related proteins in urine exosomes may serve as a potential biomarker for lung cancer diagnosis.
Jin S, Liu T, Wang W, Li T, Liu Z, Zhang M
BMC cancer 2023 Nov 18;23(1):1125
BMC cancer 2023 Nov 18;23(1):1125
PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation.
Inoue C, Mukai K, Matsudaira T, Nakayama J, Kono N, Aoki J, Arai H, Uchida Y, Taguchi T
Scientific reports 2023 Nov 13;13(1):19740
Scientific reports 2023 Nov 13;13(1):19740
ASTER-B regulates mitochondrial carotenoid transport and homeostasis.
Bandara S, Moon J, Ramkumar S, von Lintig J
Journal of lipid research 2023 May;64(5):100369
Journal of lipid research 2023 May;64(5):100369
Mesenchymal stem cells ameliorate cisplatin-induced acute kidney injury via let-7b-5p.
Wang SY, Xu Y, Hong Q, Chen XM, Cai GY
Cell and tissue research 2023 May;392(2):517-533
Cell and tissue research 2023 May;392(2):517-533
Plasma exosome-derived circGAPVD1 as a potential diagnostic marker for colorectal cancer.
Li T, Zhou T, Wu J, Lv H, Zhou H, Du M, Zhang X, Wu N, Gong S, Ren Z, Zhang P, Zhang C, Liu G, Liu X, Zhang Y
Translational oncology 2023 May;31:101652
Translational oncology 2023 May;31:101652
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Ji Y, Luo Y, Wu Y, Sun Y, Zhao L, Xue Z, Sun M, Wei X, He Z, Wu SA, Lin LL, Lu Y, Chang L, Chen F, Chen S, Qian W, Xu X, Chen S, Pan D, Zhou Z, Xia S, Hu CA, Liang T, Qi L
Nature cell biology 2023 May;25(5):726-739
Nature cell biology 2023 May;25(5):726-739
M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair.
Li L, Cao J, Li S, Cui T, Ni J, Zhang H, Zhu Y, Mao J, Gao X, Midgley AC, Zhu M, Fan G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2202964
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2202964
Testicular exosomes disturb the immunosuppressive phenotype of testicular macrophages mediated by miR-155-5p in uropathogenic Escherichia coli-induced orchitis.
Xu J, He C, Fang YW, Hu ZY, Peng ML, Chen YY, Su YF, Liu CY, Zhang HP, Zhao K
Asian journal of andrology 2023 May-Jun;25(3):389-397
Asian journal of andrology 2023 May-Jun;25(3):389-397
ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.
Yi J, Wang L, Du J, Wang M, Shen H, Liu Z, Qin Y, Liu J, Hu G, Xiao R, Ding J, Chen X, Wang H, Huang H, Ouyang G, Liu W
Developmental cell 2023 May 8;58(9):760-778.e6
Developmental cell 2023 May 8;58(9):760-778.e6
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Wu SA, Shen C, Wei X, Zhang X, Wang S, Chen X, Torres M, Lu Y, Lin LL, Wang HH, Hunter AH, Fang D, Sun S, Ivanova MI, Lin Y, Qi L
Nature communications 2023 May 30;14(1):3132
Nature communications 2023 May 30;14(1):3132
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Liu JL, Zhang L, Huang Y, Li XH, Liu YF, Zhang SM, Zhao YE, Chen XJ, Liu Y, He LY, Dong Z, Liu FY, Sun L, Xiao L
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Extracellular vesicle-mediated delivery of anti-miR-106b inhibits morphine-induced primary ciliogenesis in the brain.
Ma R, Kutchy NA, Wang Z, Hu G
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1332-1345
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1332-1345
Stress Granules Inhibit Coxsackievirus B3-Mediated Cell Death via Reduction of Mitochondrial Reactive Oxygen Species and Viral Extracellular Release.
Park JY, Shin OS
Journal of microbiology and biotechnology 2023 May 28;33(5):582-590
Journal of microbiology and biotechnology 2023 May 28;33(5):582-590
CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation.
Cheng J, Zhang G, Deng T, Liu Z, Zhang M, Zhang P, Adeshakin FO, Niu X, Yan D, Wan X, Yu G
Cell death & disease 2023 May 20;14(5):333
Cell death & disease 2023 May 20;14(5):333
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Xiao X, Shi J, He C, Bu X, Sun Y, Gao M, Xiang B, Xiong W, Dai P, Mao Q, Xing X, Yao Y, Yu H, Xu G, Li S, Ren Y, Chen B, Jiang C, Meng G, Lee YR, Wei W, Freeman GJ, Xie C, Zhang J
Nature communications 2023 May 19;14(1):2859
Nature communications 2023 May 19;14(1):2859
Extracellular Vesicles Released from Macrophages Infected with Mycoplasma pneumoniae Stimulate Proinflammatory Response via the TLR2-NF-κB/JNK Signaling Pathway.
Ma C, Hao X, Gao L, Wang Y, Shi J, Luo H, Li M
International journal of molecular sciences 2023 May 11;24(10)
International journal of molecular sciences 2023 May 11;24(10)
SERS spectroscopy with machine learning to analyze human plasma derived sEVs for coronary artery disease diagnosis and prognosis.
Huang X, Liu B, Guo S, Guo W, Liao K, Hu G, Shi W, Kuss M, Duryee MJ, Anderson DR, Lu Y, Duan B
Bioengineering & translational medicine 2023 Mar;8(2):e10420
Bioengineering & translational medicine 2023 Mar;8(2):e10420
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Chen D, Jiang X, Zou H
Journal of orthopaedic translation 2023 Mar;39:163-176
Journal of orthopaedic translation 2023 Mar;39:163-176
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Wu T, Zhu D, Wu X, Zhang N, Zhang Q
Oncology letters 2023 Mar;25(3):119
Oncology letters 2023 Mar;25(3):119
Proteomic Characterization of Peritoneal Extracellular Vesicles in a Mouse Model of Peritoneal Fibrosis.
Huang Q, Sun Y, Sun J, Peng L, Shang H, Wei D, Li C, Hu Z, Peng H
Journal of proteome research 2023 Mar 3;22(3):908-918
Journal of proteome research 2023 Mar 3;22(3):908-918
p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.
Gao J, Li A, Fujii S, Huang F, Nakatomi C, Nakamura I, Honda H, Kiyoshima T, Jimi E
Scientific reports 2023 Mar 29;13(1):5144
Scientific reports 2023 Mar 29;13(1):5144
Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps.
Wang T, Zhou Y, Zhou Z, Zhang P, Yan R, Sun L, Ma W, Zhang T, Shen S, Liu H, Lu H, Ye L, Feng J, Chen Z, Zhong X, Wu G, Cai Y, Jia W, Gao P, Zhang H
Nature communications 2023 Mar 18;14(1):1513
Nature communications 2023 Mar 18;14(1):1513
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Zhao F, Xu Y, Liu N, Lv D, Chen Y, Liu Z, Jin X, Xiao M, Lavillette D, Zhong J, Bartenschlager R, Long G
The EMBO journal 2023 Mar 15;42(6):e112096
The EMBO journal 2023 Mar 15;42(6):e112096
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
Li S, Yang K, Cao W, Guo R, Liu Z, Zhang J, Fan A, Huang Y, Ma C, Li L, Fan G
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Gong W, Guo Y, Yuan H, Chai R, Wan Z, Zheng B, Hu X, Chen B, Gao S, Dai Q, Yu P, Tu S
Cancer gene therapy 2023 Jun;30(6):905-916
Cancer gene therapy 2023 Jun;30(6):905-916
Exosomal microRNA‑4516, microRNA‑203 and SFRP1 are potential biomarkers of acute myocardial infarction.
Liu P, Wang S, Li K, Yang Y, Man Y, Du F, Wang L, Tian J, Su G
Molecular medicine reports 2023 Jun;27(6)
Molecular medicine reports 2023 Jun;27(6)
Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction.
Li L, Li F, Bai X, Jia H, Wang C, Li P, Zhang Q, Guan S, Peng R, Zhang S, Dong JF, Zhang J, Xu X
Pharmacological research 2023 Jun;192:106791
Pharmacological research 2023 Jun;192:106791
miR-142-3p encapsulated in T lymphocyte-derived tissue small extracellular vesicles induces Treg function defect and thyrocyte destruction in Hashimoto's thyroiditis.
Li G, He L, Huang J, Liu J, Chen W, Zhong J, Wei T, Li Z, Zhu J, Lei J
BMC medicine 2023 Jun 6;21(1):206
BMC medicine 2023 Jun 6;21(1):206
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
Yuan F, Peng W, Yang Y, Xu J, Liu Y, Xie Y, Huang T, Shi C, Ding Y, Li C, Qin T, Xie S, Zhu F, Lu H, Huang J, Hu J
Journal of neuroinflammation 2023 Jun 30;20(1):156
Journal of neuroinflammation 2023 Jun 30;20(1):156
TMEM41B Is an Interferon-Stimulated Gene That Promotes Pseudorabies Virus Replication.
Li XQ, Zeng L, Liang DG, Qi YL, Yang GY, Zhong K, Chu BB, Wang J
Journal of virology 2023 Jun 29;97(6):e0041223
Journal of virology 2023 Jun 29;97(6):e0041223
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
Sun Y, Zhu L, Liu P, Zhang H, Guo F, Jin X
Cancer research 2023 Jun 15;83(12):2034-2051
Cancer research 2023 Jun 15;83(12):2034-2051
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Kong Y, Wu M, Wan X, Sun M, Zhang Y, Wu Z, Li C, Liang X, Gao L, Ma C, Yue X
Redox biology 2023 Jul;63:102732
Redox biology 2023 Jul;63:102732
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies.
Guo L, Mao Q, He J, Liu X, Piao X, Luo L, Hao X, Yu H, Song Q, Xiao B, Fan D, Gao Z, Jia Y
Cell research 2023 Jul;33(7):497-515
Cell research 2023 Jul;33(7):497-515
Extracellular vesicle-packaged ILK from mesothelial cells promotes fibroblast activation in peritoneal fibrosis.
Huang Q, Sun Y, Peng L, Sun J, Sha Z, Lin H, Li Y, Li C, Li H, Shang H, Chen Y, Dou X, Hu Z, Ye Z, Peng H
Journal of extracellular vesicles 2023 Jul;12(7):e12334
Journal of extracellular vesicles 2023 Jul;12(7):e12334
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Lei Y, VanPortfliet JJ, Chen YF, Bryant JD, Li Y, Fails D, Torres-Odio S, Ragan KB, Deng J, Mohan A, Wang B, Brahms ON, Yates SD, Spencer M, Tong CW, Bosenberg MW, West LC, Shadel GS, Shutt TE, Upton JW, Li P, West AP
Cell 2023 Jul 6;186(14):3013-3032.e22
Cell 2023 Jul 6;186(14):3013-3032.e22
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Zhou M, Kong B, Zhang X, Xiao K, Lu J, Li W, Li M, Li Z, Ji W, Hou J, Xu T
iScience 2023 Jul 21;26(7):107159
iScience 2023 Jul 21;26(7):107159
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Yang S, Sun Y, Long M, Zhou X, Yuan M, Yang L, Luo W, Cheng Y, Zhang X, Jiang W, Chao J
Particle and fibre toxicology 2023 Jul 19;20(1):29
Particle and fibre toxicology 2023 Jul 19;20(1):29
Two microRNAs of plasma-derived small extracellular vesicles as biomarkers for metastatic non-small cell lung cancer.
Geng N, Qi Y, Qin W, Li S, Jin H, Jiang Y, Wang X, Wei S, Wang P
BMC pulmonary medicine 2023 Jul 14;23(1):259
BMC pulmonary medicine 2023 Jul 14;23(1):259
Changes in urinary exosomal protein CALM1 may serve as an early noninvasive biomarker for diagnosing diabetic kidney disease.
Li T, Ci Liu T, Liu N, Zhang M
Clinica chimica acta; international journal of clinical chemistry 2023 Jul 1;547:117466
Clinica chimica acta; international journal of clinical chemistry 2023 Jul 1;547:117466
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Al-Raimi HAI, Kong J, Ran Y, Zhu L, Li J, Liu X, Yang X, Qi D, Liu T
Archives of medical research 2023 Jan;54(1):27-36
Archives of medical research 2023 Jan;54(1):27-36
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Chu Q, Wang J, Du Y, Zhou T, Shi A, Xiong J, Ji WK, Deng L
Cell death and differentiation 2023 Jan;30(1):94-110
Cell death and differentiation 2023 Jan;30(1):94-110
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Liu D, Li X, Zeng B, Zhao Q, Chen H, Zhang Y, Chen Y, Wang J, Xing HR
Stem cell reviews and reports 2023 Jan;19(1):155-169
Stem cell reviews and reports 2023 Jan;19(1):155-169
Low-intensity pulsed ultrasound (LIPUS) enhances the anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles.
Li X, Zhong Y, Zhou W, Song Y, Li W, Jin Q, Gao T, Zhang L, Xie M
Cellular & molecular biology letters 2023 Jan 30;28(1):9
Cellular & molecular biology letters 2023 Jan 30;28(1):9
miR-150-5p in neutrophil-derived extracellular vesicles associated with sepsis-induced cardiomyopathy in septic patients.
Ye R, Lin Q, Xiao W, Mao L, Zhang P, Zhou L, Wu X, Jiang N, Zhang X, Zhang Y, Ma D, Huang J, Wang X, Deng L
Cell death discovery 2023 Jan 21;9(1):19
Cell death discovery 2023 Jan 21;9(1):19
A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma.
Jiang X, Deng W, Tao S, Tang Z, Chen Y, Tian M, Wang T, Tao C, Li Y, Fang Y, Pu C, Gao J, Wang X, Qu W, Gai X, Ding Z, Fu Y, Zheng Y, Cao S, Zhou J, Huang M, Liu W, Xu J, Fan J, Shi Y
Cell discovery 2023 Jan 17;9(1):7
Cell discovery 2023 Jan 17;9(1):7
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Wang J, Xu J, Dong Y, Su Z, Su H, Cheng Q, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Zou X, Liao Y, Liu Z, Xu X, Sun W, Qin H, Wang H, Liu J, Jing T
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Ye Z, Xiong Y, Peng W, Wei W, Huang L, Yue J, Zhang C, Lin G, Huang F, Zhang L, Zheng S, Yue J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
Ganji R, Paulo JA, Xi Y, Kline I, Zhu J, Clemen CS, Weihl CC, Purdy JG, Gygi SP, Raman M
Nature communications 2023 Feb 6;14(1):638
Nature communications 2023 Feb 6;14(1):638
Mesenchymal stem cells-derived exosomes ameliorate high glucose and lipopolysaccharide-induced HPMECs injury through the Nrf2/HO-1 pathway.
Sun H, Lu S, Qu G, Li J, Song B
Autoimmunity 2023 Dec;56(1):2290357
Autoimmunity 2023 Dec;56(1):2290357
Integrated transcriptomics, proteomics, and functional analysis to characterize the tissue-specific small extracellular vesicle network of breast cancer.
Shen L, Huang H, Wei Z, Chen W, Li J, Yao Y, Zhou J, Liu J, Sun S, Xia W, Zhang T, Yu X, Shen J, Wang W, Jiang J, Huang J, Jiang M, Ni C
MedComm 2023 Dec;4(6):e433
MedComm 2023 Dec;4(6):e433
Negatively charged bladder acellular matrix loaded with positively charged adipose-derived mesenchymal stem cell-derived small extracellular vesicles for bladder tissue engineering.
Yang T, Zhao F, Zhao J, Geng J, Shao C, Liu J, Sheng F, Zhou L, Xu H, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:718-733
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:718-733
SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum.
Yang M, Mariano J, Su R, Smith CE, Das S, Gill C, Andresson T, Loncarek J, Tsai YC, Weissman AM
The Journal of biological chemistry 2023 Dec;299(12):105346
The Journal of biological chemistry 2023 Dec;299(12):105346
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
Sun L, Suo C, Zhang T, Shen S, Gu X, Qiu S, Zhang P, Wei H, Ma W, Yan R, Chen R, Jia W, Cao J, Zhang H, Gao P
Nature chemical biology 2023 Dec;19(12):1492-1503
Nature chemical biology 2023 Dec;19(12):1492-1503
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10.
Liu X, Jin S, Liu J, Xu X
Acta histochemica 2023 Dec;125(8):152102
Acta histochemica 2023 Dec;125(8):152102
Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization.
Yao Y, Chen C, Wang J, Xuan H, Chen X, Li Z, Yang F, Wang B, Lin S, Li S, Tang D, Gong L, Gao W
Journal of experimental & clinical cancer research : CR 2023 Dec 5;42(1):330
Journal of experimental & clinical cancer research : CR 2023 Dec 5;42(1):330
Extracellular vesicles long RNA profiling identifies abundant mRNA, circRNA and lncRNA in human bile as potential biomarkers for cancer diagnosis.
Zong H, Yu W, Lai H, Chen B, Zhang H, Zhao J, Huang S, Li Y
Carcinogenesis 2023 Dec 2;44(8-9):671-681
Carcinogenesis 2023 Dec 2;44(8-9):671-681
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
MiR-146b-5p enriched bioinspired exosomes derived from fucoidan-directed induction mesenchymal stem cells protect chondrocytes in osteoarthritis by targeting TRAF6.
Lou C, Jiang H, Lin Z, Xia T, Wang W, Lin C, Zhang Z, Fu H, Iqbal S, Liu H, Lin J, Wang J, Pan X, Xue X
Journal of nanobiotechnology 2023 Dec 18;21(1):486
Journal of nanobiotechnology 2023 Dec 18;21(1):486
Cultured lymphocytes' mitochondrial genome integrity is not altered by cladribine.
Järvinen E, Suomi F, Stewart JB, Guala D, Valori M, Jansson L, Nieminen J, McWilliams TG, Tienari PJ
Clinical and experimental immunology 2023 Dec 13;214(3):304-313
Clinical and experimental immunology 2023 Dec 13;214(3):304-313
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Huang J, Ding M, Lu Y, Xu L, Zhang Y, Han S, Zhu X, Li Y, Chen P
Cell death & disease 2023 Dec 1;14(12):789
Cell death & disease 2023 Dec 1;14(12):789
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease.
Salazar-Puerta AI, Kordowski M, Cuellar-Gaviria TZ, Rincon-Benavides MA, Hussein J, Flemister D, Mayoral-Andrade G, Barringer G, Guilfoyle E, Blackstone BN, Deng B, Zepeda-Orozco D, McComb DW, Powell H, Dasi LP, Gallego-Perez D, Higuita-Castro N
Cellular and molecular bioengineering 2023 Aug;16(4):309-324
Cellular and molecular bioengineering 2023 Aug;16(4):309-324
The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity.
Chen T, Feng Y, Sun W, Zhao G, Wu H, Cheng X, Zhao F, Zhang L, Zheng Y, Zhan P, Zhao W, Liu B, Gao C
Immunity 2023 Aug 8;56(8):1727-1742.e6
Immunity 2023 Aug 8;56(8):1727-1742.e6
Tumor-Associated Extracellular Microvesicles with Fluorine-Modified Carbohydrate Antigens Trigger a Stronger Antitumor Immune Response.
Mo J, Zou Y, Li BH, Li G, Zheng XJ, Liu Y, Ye XS
ACS applied materials & interfaces 2023 Aug 30;15(34):40201-40212
ACS applied materials & interfaces 2023 Aug 30;15(34):40201-40212
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling.
Liu X, Li J, Yang X, Li X, Kong J, Qi D, Zhang F, Sun B, Liu Y, Liu T
International journal of oral science 2023 Aug 2;15(1):32
International journal of oral science 2023 Aug 2;15(1):32
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Shi J, Wang W, Sun S, Xu X, Fei J, Zhou Q, Qin C, Ou S, Wu F, Wu FT, Xu T, Bai L, Xie F
iScience 2023 Aug 18;26(8):107312
iScience 2023 Aug 18;26(8):107312
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y
The EMBO journal 2023 Aug 15;42(16):e113258
The EMBO journal 2023 Aug 15;42(16):e113258
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Wang J, Cheng Q, Zhang Y, Hong C, Liu J, Liu X, Chang J
Aging and disease 2023 Aug 1;14(4):1458-1471
Aging and disease 2023 Aug 1;14(4):1458-1471
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Qiu S, Zhong X, Meng X, Li S, Qian X, Lu H, Cai J, Zhang Y, Wang M, Ye Z, Zhang H, Gao P
Cell research 2023 Apr;33(4):299-311
Cell research 2023 Apr;33(4):299-311
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
Gui X, Zhang H, Zhang R, Li Q, Zhu W, Nie Z, Zhao J, Cui X, Hao W, Wen X, Shen W, Song H
Materials today. Bio 2023 Apr;19:100602
Materials today. Bio 2023 Apr;19:100602
MicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacy.
Zhang Y, Huang X, Sun T, Shi L, Liu B, Hong Y, Fu QL, Zhang Y, Li X
Journal of nanobiotechnology 2023 Apr 26;21(1):135
Journal of nanobiotechnology 2023 Apr 26;21(1):135
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
Wang YJ, Seibert H, Ahn LY, Schaffer AE, Mu TW
bioRxiv : the preprint server for biology 2023 Apr 19;
bioRxiv : the preprint server for biology 2023 Apr 19;
Pigmentation and TYRP1 expression are mediated by zinc through the early secretory pathway-resident ZNT proteins.
Wagatsuma T, Suzuki E, Shiotsu M, Sogo A, Nishito Y, Ando H, Hashimoto H, Petris MJ, Kinoshita M, Kambe T
Communications biology 2023 Apr 18;6(1):403
Communications biology 2023 Apr 18;6(1):403
Phenylethanoid glycosides extract from Cistanche deserticola ameliorates atherosclerosis in apolipoprotein E-deficient mice and regulates intestinal PPARγ-LXRα-ABCA1 pathway.
Jia X, Liu B, Xue J, Liu Y, Zhang J, Qin S, Zhang Y
The Journal of pharmacy and pharmacology 2023 Apr 17;75(5):677-685
The Journal of pharmacy and pharmacology 2023 Apr 17;75(5):677-685
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Lu J, Yang X, He C, Chen Y, Li C, Li S, Chen Y, Wu Y, Xiang Z, Kang J, Jiang G, Wang C, Diarra MD, He R, Feng G, Yan R
Acta biomaterialia 2023 Apr 15;161:80-99
Acta biomaterialia 2023 Apr 15;161:80-99
Signal-Retaining Autophagy Indicator as a Quantitative Imaging Method for ER-Phagy.
Jimenez-Moreno N, Salomo-Coll C, Murphy LC, Wilkinson S
Cells 2023 Apr 11;12(8)
Cells 2023 Apr 11;12(8)
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Geng J, Khaket TP, Pan J, Li W, Zhang Y, Ping Y, Cobos Sillero MI, Lu B
Developmental cell 2023 Apr 10;58(7):597-615.e10
Developmental cell 2023 Apr 10;58(7):597-615.e10
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
Wang S, Shi M, Zhou J, Wang W, Zhang Y, Li Y
Frontiers in cardiovascular medicine 2022;9:844047
Frontiers in cardiovascular medicine 2022;9:844047
miR-29a-3p in Exosomes from Heme Oxygenase-1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia-Reperfusion Injury in Rats by Suppressing Ferroptosis via Iron Responsive Element Binding Protein 2.
Li X, Wu L, Tian X, Zheng W, Yuan M, Tian X, Zuo H, Song H, Shen Z
Oxidative medicine and cellular longevity 2022;2022:6520789
Oxidative medicine and cellular longevity 2022;2022:6520789
Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation.
Jiang J, Yang C, Ai JQ, Zhang QL, Cai XL, Tu T, Wan L, Wang XS, Wang H, Pan A, Manavis J, Gai WP, Che C, Tu E, Wang XP, Li ZY, Yan XX
Frontiers in aging neuroscience 2022;14:926904
Frontiers in aging neuroscience 2022;14:926904
The potential role of exosomal miRNAs and membrane proteins in acute HIV-infected people.
Li X, Wang W, Chen J, Xie B, Luo S, Chen D, Cai C, Li C, Li W
Frontiers in immunology 2022;13:939504
Frontiers in immunology 2022;13:939504
Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain.
Kutchy NA, Ma R, Liu Y, Buch S, Hu G
Frontiers in pharmacology 2022;13:819516
Frontiers in pharmacology 2022;13:819516
Characterization and subcellular localization of Alongshan virus proteins.
Zhao Y, Wu P, Liu L, Ma B, Pan M, Huang Y, Du N, Yu H, Sui L, Wang ZD, Hou Z, Liu Q
Frontiers in microbiology 2022;13:1000322
Frontiers in microbiology 2022;13:1000322
Exosomal CD44 Transmits Lymph Node Metastatic Capacity Between Gastric Cancer Cells via YAP-CPT1A-Mediated FAO Reprogramming.
Wang M, Yu W, Cao X, Gu H, Huang J, Wu C, Wang L, Sha X, Shen B, Wang T, Yao Y, Zhu W, Huang F
Frontiers in oncology 2022;12:860175
Frontiers in oncology 2022;12:860175
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Liang S, Zhu C, Suo C, Wei H, Yu Y, Gu X, Chen L, Yuan M, Shen S, Li S, Sun L, Gao P
Frontiers in oncology 2022;12:857968
Frontiers in oncology 2022;12:857968
Hypoxic Cell-Derived Extracellular Vesicles Aggravate Rectal Injury Following Radiotherapy via MiR-122-5p.
Xu Y, Ge Y, Chen X, Zhang Y, Chen H, Liu D, Lu Y, Liu Y, Tu W
Frontiers in cell and developmental biology 2022;10:892575
Frontiers in cell and developmental biology 2022;10:892575
The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formation.
Shindo R, Kuchitsu Y, Mukai K, Taguchi T
Frontiers in cell and developmental biology 2022;10:1037999
Frontiers in cell and developmental biology 2022;10:1037999
Phospholipid peroxidation inhibits autophagy via stimulating the delipidation of oxidized LC3-PE.
Li W, Luo LX, Zhou QQ, Gong HB, Fu YY, Yan CY, Li E, Sun J, Luo Z, Ding ZJ, Zhang QY, Mu HL, Cao YF, Ouyang SH, Kurihara H, Li YF, Sun WY, Li M, He RR
Redox biology 2022 Sep;55:102421
Redox biology 2022 Sep;55:102421
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Khodayari N, Oshins R, Mehrad B, Lascano JE, Qiang X, West JR, Holliday LS, Lee J, Wiesemann G, Eydgahi S, Brantly M
Respiratory research 2022 Sep 6;23(1):232
Respiratory research 2022 Sep 6;23(1):232
De novo sphingolipid biosynthesis necessitates detoxification in cancer cells.
Spears ME, Lee N, Hwang S, Park SJ, Carlisle AE, Li R, Doshi MB, Armando AM, Gao J, Simin K, Zhu LJ, Greer PL, Quehenberger O, Torres EM, Kim D
Cell reports 2022 Sep 27;40(13):111415
Cell reports 2022 Sep 27;40(13):111415
TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.
Wang L, Li J, Wang Q, Ge MX, Ji J, Liu D, Wang Z, Cao Y, Zhang Y, Zhang ZR
Molecular cell 2022 Sep 15;82(18):3453-3467.e14
Molecular cell 2022 Sep 15;82(18):3453-3467.e14
TMEΜ45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication.
Yan F, Yang W, Wang X, Gao G
Journal of virology 2022 Sep 14;96(17):e0091922
Journal of virology 2022 Sep 14;96(17):e0091922
TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia.
Tábara LC, Al-Salmi F, Maroofian R, Al-Futaisi AM, Al-Murshedi F, Kennedy J, Day JO, Courtin T, Al-Khayat A, Galedari H, Mazaheri N, Protasoni M, Johnson M, Leslie JS, Salter CG, Rawlins LE, Fasham J, Al-Maawali A, Voutsina N, Charles P, Harrold L, Keren B, Kunji ERS, Vona B, Jelodar G, Sedaghat A, Shariati G, Houlden H, Crosby AH, Prudent J, Baple EL
Brain : a journal of neurology 2022 Sep 14;145(9):3095-3107
Brain : a journal of neurology 2022 Sep 14;145(9):3095-3107
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN, Zhao XJ, Wang Z, Luo MS, Shi SN, Yan DM, Li HY, Liu JH, Yang Y, Tan JH, Zhang ZY, Chen RQ, Lai HL, Huang XY, Zhou JF, Ma D, Fang Y, Gao QL
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.
Zheng S, Lin J, Pang Z, Zhang H, Wang Y, Ma L, Zhang H, Zhang X, Chen M, Zhang X, Zhao C, Qi J, Cao L, Wang M, He X, Sheng R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(28):e2200750
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(28):e2200750
The role of hepatic Surf4 in lipoprotein metabolism and the development of atherosclerosis in apoE(-/-) mice.
Shen Y, Gu HM, Zhai L, Wang B, Qin S, Zhang DW
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Oct;1867(10):159196
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Oct;1867(10):159196
The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 pathway following hypoxia-ischemia in neonatal mice.
Xin DQ, Zhao YJ, Li TT, Ke HF, Gai CC, Guo XF, Chen WQ, Liu DX, Wang Z
Neural regeneration research 2022 Oct;17(10):2238-2246
Neural regeneration research 2022 Oct;17(10):2238-2246
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Wang R, Shang Y, Chen B, Xu F, Zhang J, Zhang Z, Zhao X, Wan X, Xu A, Wu L, Zhao G
Cell death & disease 2022 Oct 6;13(10):851
Cell death & disease 2022 Oct 6;13(10):851
Mutated lncRNA increase the risk of type 2 diabetes by promoting β cell dysfunction and insulin resistance.
Guo WH, Guo Q, Liu YL, Yan DD, Jin L, Zhang R, Yan J, Luo XH, Yang M
Cell death & disease 2022 Oct 27;13(10):904
Cell death & disease 2022 Oct 27;13(10):904
Extracellular vesicles derived from endometrial epithelial cells deliver exogenous miR-92b-3p to affect the function of embryonic trophoblast cells via targeting TSC1 and DKK3.
Hua R, Liu Q, Lian W, Kang TT, Gao D, Huang C, Wang Y, Lei M
Reproductive biology and endocrinology : RB&E 2022 Oct 25;20(1):152
Reproductive biology and endocrinology : RB&E 2022 Oct 25;20(1):152
Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy.
Ma Q, Beal JR, Song X, Bhurke A, Bagchi IC, Bagchi MK
Endocrinology 2022 Oct 23;163(12)
Endocrinology 2022 Oct 23;163(12)
Proteomic and miRNA Profiles of Exosomes Derived from Myometrial Tissue in Laboring Women.
Deng W, Wang X, Chen L, Wen B, Chen Y, Ji K, Liu H
International journal of molecular sciences 2022 Oct 15;23(20)
International journal of molecular sciences 2022 Oct 15;23(20)
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Li X, Liu D, Chen H, Zeng B, Zhao Q, Zhang Y, Chen Y, Wang J, Xing HR
Biological research 2022 Oct 1;55(1):29
Biological research 2022 Oct 1;55(1):29
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Han L, Zheng Y, Deng J, Nan ML, Xiao Y, Zhuang MW, Zhang J, Wang W, Gao C, Wang PH
Journal of medical virology 2022 Nov;94(11):5174-5188
Journal of medical virology 2022 Nov;94(11):5174-5188
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.
Strohm L, Hu Z, Suk Y, Rühmkorf A, Sternburg E, Gattringer V, Riemenschneider H, Berutti R, Graf E, Weishaupt JH, Brill MS, Harbauer AB, Dormann D, Dengjel J, Edbauer D, Behrends C
Life science alliance 2022 Nov;5(11)
Life science alliance 2022 Nov;5(11)
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection.
Zhang X, Yang Z, Pan T, Long X, Sun Q, Wang PH, Li X, Kuang E
Autophagy 2022 Nov;18(11):2576-2592
Autophagy 2022 Nov;18(11):2576-2592
Extracellular vesicles from human urine-derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration.
Zhuang J, Gao P, Chen H, Fang Z, Zheng J, Zhu D, Hou J
Andrology 2022 Nov;10(8):1673-1686
Andrology 2022 Nov;10(8):1673-1686
Plasma Extracellular Vesicle Long RNA in Diagnosis and Prediction in Small Cell Lung Cancer.
Liu C, Chen J, Liao J, Li Y, Yu H, Zhao X, Sun S, Hu Z, Zhang Y, Zhu Z, Fan M, Huang S, Wang J
Cancers 2022 Nov 9;14(22)
Cancers 2022 Nov 9;14(22)
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1.
Cen X, Chen Q, Wang B, Xu H, Wang X, Ling Y, Zhang X, Qin D
Cell communication and signaling : CCS 2022 Nov 28;20(1):191
Cell communication and signaling : CCS 2022 Nov 28;20(1):191
Extracellular vesicle-derived long non-coding RNA as circulating biomarkers for endometriosis.
Shan S, Yang Y, Jiang J, Yang B, Yang Y, Sun F, Zhang J, Lin Y, Xu H
Reproductive biomedicine online 2022 May;44(5):923-933
Reproductive biomedicine online 2022 May;44(5):923-933
The endoplasmic reticulum adopts two distinct tubule forms.
Wang B, Zhao Z, Xiong M, Yan R, Xu K
Proceedings of the National Academy of Sciences of the United States of America 2022 May 3;119(18):e2117559119
Proceedings of the National Academy of Sciences of the United States of America 2022 May 3;119(18):e2117559119
Autophagic LC3(+) calcified extracellular vesicles initiate cartilage calcification in osteoarthritis.
Yan J, Shen M, Sui B, Lu W, Han X, Wan Q, Liu Y, Kang J, Qin W, Zhang Z, Chen D, Cao Y, Ying S, Tay FR, Niu LN, Jiao K
Science advances 2022 May 13;8(19):eabn1556
Science advances 2022 May 13;8(19):eabn1556
Evaluation of plasma exosomal miRNAs as potential diagnostic biomarkers of lymph node metastasis in papillary thyroid carcinoma.
Chen W, Li G, Li Z, Zhu J, Wei T, Lei J
Endocrine 2022 Mar;75(3):846-855
Endocrine 2022 Mar;75(3):846-855
Photobiomodulation promotes hair regeneration in injured skin by enhancing migration and exosome secretion of dermal papilla cells.
Zhang Y, Su J, Ma K, Li H, Fu X, Zhang C
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2022 Mar;30(2):245-257
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2022 Mar;30(2):245-257
ESCRT dysfunction compromises endoplasmic reticulum maturation and autophagosome biogenesis in Drosophila.
Wang R, Miao G, Shen JL, Fortier TM, Baehrecke EH
Current biology : CB 2022 Mar 28;32(6):1262-1274.e4
Current biology : CB 2022 Mar 28;32(6):1262-1274.e4
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
Zhao Y, Hu D, Wang R, Sun X, Ropelewski P, Hubler Z, Lundberg K, Wang Q, Adams DJ, Xu R, Qi X
Nature communications 2022 Mar 2;13(1):1121
Nature communications 2022 Mar 2;13(1):1121
N-terminome analyses underscore the prevalence of SPPL3-mediated intramembrane proteolysis among Golgi-resident enzymes and its role in Golgi enzyme secretion.
Hobohm L, Koudelka T, Bahr FH, Truberg J, Kapell S, Schacht SS, Meisinger D, Mengel M, Jochimsen A, Hofmann A, Heintz L, Tholey A, Voss M
Cellular and molecular life sciences : CMLS 2022 Mar 13;79(3):185
Cellular and molecular life sciences : CMLS 2022 Mar 13;79(3):185
MOSPD2 is an endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis.
Zouiouich M, Di Mattia T, Martinet A, Eichler J, Wendling C, Tomishige N, Grandgirard E, Fuggetta N, Fromental-Ramain C, Mizzon G, Dumesnil C, Carpentier M, Reina-San-Martin B, Mathelin C, Schwab Y, Thiam AR, Kobayashi T, Drin G, Tomasetto C, Alpy F
The Journal of cell biology 2022 Jun 6;221(6)
The Journal of cell biology 2022 Jun 6;221(6)
Preparation of Recombinant Human Collagen III Protein Hydrogels with Sustained Release of Extracellular Vesicles for Skin Wound Healing.
Xu L, Liu Y, Tang L, Xiao H, Yang Z, Wang S
International journal of molecular sciences 2022 Jun 3;23(11)
International journal of molecular sciences 2022 Jun 3;23(11)
Micro-RNAs from Plasma-Derived Small Extracellular Vesicles as Potential Biomarkers for Tic Disorders Diagnosis.
Wang Y, Xu X, Chen H, Zhu M, Guo X, Gao F
Brain sciences 2022 Jun 26;12(7)
Brain sciences 2022 Jun 26;12(7)
Exosomal tRF-Leu-AAG-001 derived from mast cell as a potential non-invasive diagnostic biomarker for endometriosis.
Li Y, Cui S, Xu Z, Zhang Y, Wu T, Zhang J, Chen Y
BMC women's health 2022 Jun 25;22(1):253
BMC women's health 2022 Jun 25;22(1):253
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Yan JM, Zhang WK, Yan LN, Jiao YJ, Zhou CM, Yu XJ
Autophagy 2022 Jul;18(7):1599-1612
Autophagy 2022 Jul;18(7):1599-1612
Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.
Chen P, Tang S, Gao H, Zhang H, Chen C, Fang Z, Peng G, Weng H, Chen A, Zhang C, Qiu Z, Li S, Chen J, Chen L, Chen X
International journal of pharmaceutics 2022 Jul 25;623:121952
International journal of pharmaceutics 2022 Jul 25;623:121952
FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia.
Mei F, Hu J, Wu Z, Zhang G, Liu A, Li X, Zhu M, Gan Y, Liang L, Zhao X, Yuan Y, Meng X, Li Y, Jin Y, Jia J, Yin Y
Cell reports 2022 Jul 19;40(3):111101
Cell reports 2022 Jul 19;40(3):111101
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Zhou H, Shen X, Yan C, Xiong W, Ma Z, Tan Z, Wang J, Li Y, Liu J, Duan A, Liu F
Stem cell research & therapy 2022 Jul 16;13(1):322
Stem cell research & therapy 2022 Jul 16;13(1):322
The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice.
Nozawa K, Fujihara Y, Devlin DJ, Deras RE, Kent K, Larina IV, Umezu K, Yu Z, Sutton CM, Ye Q, Dean LK, Emori C, Ikawa M, Garcia TX, Matzuk MM
BMC biology 2022 Jul 13;20(1):161
BMC biology 2022 Jul 13;20(1):161
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Chen B, Qin G, Xiao J, Deng X, Lin A, Liu H
Journal of neuroinflammation 2022 Jul 13;19(1):181
Journal of neuroinflammation 2022 Jul 13;19(1):181
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89
Nature cancer 2022 Jan;3(1):75-89
Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease.
Carrascal M, Areny-Balagueró A, de-Madaria E, Cárdenas-Jaén K, García-Rayado G, Rivera R, Martin Mateos RM, Pascual-Moreno I, Gironella M, Abian J, Closa D
The Journal of pathology 2022 Jan;256(1):83-92
The Journal of pathology 2022 Jan;256(1):83-92
Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.
Fu J, Zhou M, Gritsenko MA, Nakayasu ES, Song L, Luo ZQ
eLife 2022 Jan 27;11
eLife 2022 Jan 27;11
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Zheng Y, Deng J, Han L, Zhuang MW, Xu Y, Zhang J, Nan ML, Xiao Y, Zhan P, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2022 Jan 24;7(1):22
Signal transduction and targeted therapy 2022 Jan 24;7(1):22
Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p.
Gao Y, Yin Z, Qi Y, Peng H, Ma W, Wang R, Li W
Cancer cell international 2022 Jan 24;22(1):35
Cancer cell international 2022 Jan 24;22(1):35
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Shi J, Li Z, Xu R, Zhang J, Zhou Q, Gao R, Lu H, Lan Y, Zhao K, He H, Gao F, He W
Journal of virology 2022 Jan 12;96(1):e0169521
Journal of virology 2022 Jan 12;96(1):e0169521
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Bryant JD, Lei Y, VanPortfliet JJ, Winters AD, West AP
Current protocols 2022 Feb;2(2):e372
Current protocols 2022 Feb;2(2):e372
Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication.
Zhang Y, Yu X, Sun R, Min J, Tang X, Lin Z, Xie S, Li X, Lu S, Tian Z, Gu C, Teng L, Yang Y
Clinical and translational medicine 2022 Feb;12(2):e684
Clinical and translational medicine 2022 Feb;12(2):e684
Plasma extracellular vesicle microRNA profiling and the identification of a diagnostic signature for stage I lung adenocarcinoma.
Gao S, Guo W, Liu T, Liang N, Ma Q, Gao Y, Tan F, Xue Q, He J
Cancer science 2022 Feb;113(2):648-659
Cancer science 2022 Feb;113(2):648-659
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
Bian M, Fan R, Yang Z, Chen Y, Xu Z, Lu Y, Liu W
Journal of medicinal chemistry 2022 Feb 10;65(3):1848-1866
Journal of medicinal chemistry 2022 Feb 10;65(3):1848-1866
Atrophic skeletal muscle fibre-derived small extracellular vesicle miR-690 inhibits satellite cell differentiation during ageing.
Shao X, Gong W, Wang Q, Wang P, Shi T, Mahmut A, Qin J, Yao Y, Yan W, Chen D, Chen X, Jiang Q, Guo B
Journal of cachexia, sarcopenia and muscle 2022 Dec;13(6):3163-3180
Journal of cachexia, sarcopenia and muscle 2022 Dec;13(6):3163-3180
Identification of Circulating Exosomal microRNAs Associated with Radioiodine Refractory in Papillary Thyroid Carcinoma.
Li G, Chen W, Gong Y, Wei T, Gong R, Zhu J, Li Z, Lei J
Journal of personalized medicine 2022 Dec 7;12(12)
Journal of personalized medicine 2022 Dec 7;12(12)
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Ding Y, Hu Q, Gan J, Zang X, Gu T, Wu Z, Cai G, Hong L
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Exosomes from the Uterine Cavity Mediate Immune Dysregulation via Inhibiting the JNK Signal Pathway in Endometriosis.
Jiang Y, Chai X, Chen S, Chen Z, Tian H, Liu M, Wu X
Biomedicines 2022 Dec 2;10(12)
Biomedicines 2022 Dec 2;10(12)
A cryostat-based frozen section method to increase the yield of extracellular vesicles extracted from different tissues.
Yang S, Qin W, Li X, Guo Q, Wang Y, Chen J, Li H, Zhang S, Min L
BioTechniques 2022 Aug;73(2):90-98
BioTechniques 2022 Aug;73(2):90-98
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Ge X, He Z, Cao C, Xue T, Jing J, Ma R, Zhao W, Liu L, Jueraitetibaike K, Ma J, Feng Y, Qian Z, Zou Z, Chen L, Fu C, Song N, Yao B
Redox biology 2022 Aug;54:102380
Redox biology 2022 Aug;54:102380
Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency.
Wang F, Yang Y, Boudagh G, Eskelinen EL, Klionsky DJ, Malek SN
Autophagy 2022 Aug;18(8):1982-2000
Autophagy 2022 Aug;18(8):1982-2000
Differential proteomic analysis of plasma-derived exosomes as diagnostic biomarkers for chronic HBV-related liver disease.
Ye B, Shen Y, Chen H, Lin S, Mao W, Dong Y, Li X
Scientific reports 2022 Aug 24;12(1):14428
Scientific reports 2022 Aug 24;12(1):14428
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Li C, Li R, Hu X, Zhou G, Jiang G
Breast cancer research and treatment 2022 Apr;192(2):353-368
Breast cancer research and treatment 2022 Apr;192(2):353-368
Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.
Liu W, Feng Y, Wang X, Ding J, Li H, Guan H, Chen Z
Bioengineered 2022 Apr;13(4):8850-8865
Bioengineered 2022 Apr;13(4):8850-8865
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
Zhao Q, Chen H, Li X, Zeng B, Sun Z, Liu D, Chen Y, Zhang Y, Rosie Xing H, Wang J
Cell death discovery 2022 Apr 9;8(1):188
Cell death discovery 2022 Apr 9;8(1):188
miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.
Wu L, Tian X, Zuo H, Zheng W, Li X, Yuan M, Tian X, Song H
Journal of nanobiotechnology 2022 Apr 22;20(1):196
Journal of nanobiotechnology 2022 Apr 22;20(1):196
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.
Dong X, Jiang D, Wang L, Zhao J, Yu L, Huang Y, Wu X, Zhu Y, Zhao Y, Zhao Q, Zhang G, Li X
iScience 2022 Apr 15;25(4):104042
iScience 2022 Apr 15;25(4):104042
Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration.
Li S, Liao Z, Luo R, Song Y, Wang K, Feng X, Ou Y, Wu X, Zhang Y, Gao Y, Yin H, Yang C
Frontiers in cell and developmental biology 2021;9:672847
Frontiers in cell and developmental biology 2021;9:672847
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Yang W, Tu H, Tang K, Huang H, Ou S, Wu J
Frontiers in cardiovascular medicine 2021;8:709079
Frontiers in cardiovascular medicine 2021;8:709079
Identification of the Association Between Toll-Like Receptors and T-Cell Activation in Takayasu's Arteritis.
Tian Y, Huang B, Li J, Tian X, Zeng X
Frontiers in immunology 2021;12:792901
Frontiers in immunology 2021;12:792901
GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity.
Guo S, Gu J, Ma J, Xu R, Wu Q, Meng L, Liu H, Li L, Xu Y
Theranostics 2021;11(17):8379-8395
Theranostics 2021;11(17):8379-8395
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Xiong J, Wu L, Huang L, Wu C, Liu Z, Deng W, Ma S, Zhou Z, Yu H, Cao K
Frontiers in oncology 2021;11:718876
Frontiers in oncology 2021;11:718876
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Han L, Zhuang MW, Deng J, Zheng Y, Zhang J, Nan ML, Zhang XJ, Gao C, Wang PH
Journal of medical virology 2021 Sep;93(9):5376-5389
Journal of medical virology 2021 Sep;93(9):5376-5389
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Huang J, Yu M, Yin W, Liang B, Li A, Li J, Li X, Zhao S, Liu F
Bioactive materials 2021 Sep;6(9):2841-2853
Bioactive materials 2021 Sep;6(9):2841-2853
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Liu H, Chen B, Guo B, Deng X, Wang B, Dou X
Molecular neurobiology 2021 Sep;58(9):4251-4267
Molecular neurobiology 2021 Sep;58(9):4251-4267
Neuronal Exosomes Secreted under Oxygen-Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth.
Chiang CS, Fu SJ, Hsu CL, Jeng CJ, Tang CY, Huang YS, Tang SC
Neuromolecular medicine 2021 Sep;23(3):404-415
Neuromolecular medicine 2021 Sep;23(3):404-415
Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.
Jia W, Zou X, Xu Z, Bai L, Shan A, Li Y, Shi J, Yang F, Ding C, Narimatsu H, Zhang Y
Glycobiology 2021 Sep 9;31(8):947-958
Glycobiology 2021 Sep 9;31(8):947-958
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
Xie Y, Liu G, Zang X, Hu Q, Zhou C, Li Y, Liu D, Hong L
Cells 2021 Sep 3;10(9)
Cells 2021 Sep 3;10(9)
Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence.
Zheng H, Liang X, Han Q, Shao Z, Zhang Y, Shi L, Hong Y, Li W, Mai C, Mo Q, Fu Q, Ma X, Lin F, Li M, Hu B, Li X, Zhang Y
Journal of nanobiotechnology 2021 Oct 21;19(1):332
Journal of nanobiotechnology 2021 Oct 21;19(1):332
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Rimal S, Li Y, Vartak R, Geng J, Tantray I, Li S, Huh S, Vogel H, Glabe C, Grinberg LT, Spina S, Seeley WW, Guo S, Lu B
Acta neuropathologica communications 2021 Oct 18;9(1):169
Acta neuropathologica communications 2021 Oct 18;9(1):169
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation.
Zhang X, Qu YY, Liu L, Qiao YN, Geng HR, Lin Y, Xu W, Cao J, Zhao JY
Cell reports 2021 Oct 12;37(2):109821
Cell reports 2021 Oct 12;37(2):109821
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Cheng L, Yu P, Li F, Jiang X, Jiao X, Shen Y, Lai X
Human cell 2021 Nov;34(6):1697-1708
Human cell 2021 Nov;34(6):1697-1708
Hypercholesterolemia risk associated Abca6 does not regulate lipoprotein metabolism in mice or hamster.
He B, Kang S, Chen Z, Liu X, Wang J, Li X, Liu X, Zheng L, Luo M, Wang Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Nov;1866(11):159006
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Nov;1866(11):159006
Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.
Ding Q, Jin M, Kalds P, Meng C, Wang H, Zhong J, Wang X, Chen Y
Animals : an open access journal from MDPI 2021 Nov 8;11(11)
Animals : an open access journal from MDPI 2021 Nov 8;11(11)
hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression.
Li C, Qin F, Wang W, Ni Y, Gao M, Guo M, Sun G
International journal of molecular sciences 2021 Nov 28;22(23)
International journal of molecular sciences 2021 Nov 28;22(23)
AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway.
Mak HY, Ouyang Q, Tumanov S, Xu J, Rong P, Dong F, Lam SM, Wang X, Lukmantara I, Du X, Gao M, Brown AJ, Gong X, Shui G, Stocker R, Huang X, Chen S, Yang H
Nature communications 2021 Nov 25;12(1):6877
Nature communications 2021 Nov 25;12(1):6877
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Long F, Yang D, Wang J, Wang Q, Ni T, Wei G, Zhu Y, Liu X
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins.
Chen F, Yan B, Ren J, Lyu R, Wu Y, Guo Y, Li D, Zhang H, Hu J
The Journal of cell biology 2021 May 3;220(5)
The Journal of cell biology 2021 May 3;220(5)
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
Zhang J, Huang F, Xia B, Yuan Y, Yu F, Wang G, Chen Q, Wang Q, Li Y, Li R, Song Z, Pan T, Chen J, Lu G, Zhang H
Signal transduction and targeted therapy 2021 May 12;6(1):189
Signal transduction and targeted therapy 2021 May 12;6(1):189
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Shi M, Huang XY, Ren XY, Wei XY, Ma Y, Lin ZZ, Liu DT, Song L, Zhao TJ, Li G, Yao L, Zhu M, Zhang C, Xie C, Wu Y, Wu HM, Fan LP, Ou J, Zhan YH, Lin SY, Lin SC
Nature cell biology 2021 Mar;23(3):268-277
Nature cell biology 2021 Mar;23(3):268-277
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι.
Zhang Y, Chen Y, Li Y, Huang F, Luo B, Yuan Y, Xia B, Ma X, Yang T, Yu F, Liu J, Liu B, Song Z, Chen J, Yan S, Wu L, Pan T, Zhang X, Li R, Huang W, He X, Xiao F, Zhang J, Zhang H
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 8;118(23)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 8;118(23)
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation.
Takahashi K, Niki T, Ogawa E, Fumika K, Nishioka Y, Sawa M, Arai H, Mukai K, Taguchi T
Scientific reports 2021 Jun 7;11(1):11996
Scientific reports 2021 Jun 7;11(1):11996
Identification of exosome miRNAs in bronchial epithelial cells after PM2.5 chronic exposure.
Wang Y, Zhong Y, Sun K, Fan Y, Liao J, Wang G
Ecotoxicology and environmental safety 2021 Jun 1;215:112127
Ecotoxicology and environmental safety 2021 Jun 1;215:112127
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Chai P, Cheng Y, Hou C, Yin L, Zhang D, Hu Y, Chen Q, Zheng P, Teng J, Chen J
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Huang R, Hao C, Wang D, Zhao Q, Li C, Wang C, Yao W
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Secretome of Activated Fibroblasts Induced by Exosomes for the Discovery of Biomarkers in Non-Small Cell Lung Cancer.
Zhang J, Fu B, Li M, Mi S
Small (Weinheim an der Bergstrasse, Germany) 2021 Jan;17(4):e2004750
Small (Weinheim an der Bergstrasse, Germany) 2021 Jan;17(4):e2004750
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Yang J, Cao LL, Wang XP, Guo W, Guo RB, Sun YQ, Xue TF, Cai ZY, Ji J, Cheng H, Sun XL
Cell death & disease 2021 Jan 6;12(1):23
Cell death & disease 2021 Jan 6;12(1):23
Small RNA-seq analysis of extracellular vesicles from porcine uterine flushing fluids during peri-implantation.
Hua R, Wang Y, Lian W, Li W, Xi Y, Xue S, Kang T, Lei M
Gene 2021 Jan 15;766:145117
Gene 2021 Jan 15;766:145117
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322
Pharmacological research 2021 Feb;164:105322
GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease.
Cerri S, Ghezzi C, Ongari G, Croce S, Avenali M, Zangaglia R, Di Monte DA, Valente EM, Blandini F
International journal of molecular sciences 2021 Feb 23;22(4)
International journal of molecular sciences 2021 Feb 23;22(4)
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1.
Deng Y, Tong J, Shi W, Tian Z, Yu B, Tang J
Annals of medicine 2021 Dec;53(1):1129-1141
Annals of medicine 2021 Dec;53(1):1129-1141
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Chen Y, Hu M, Deng F, Wang P, Lin J, Zheng Z, Liu Y, Dong L, Lu X, Chen Z, Zhou J, Zuo D
Cell calcium 2021 Dec;100:102477
Cell calcium 2021 Dec;100:102477
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
Liu SJ, Meng MY, Han S, Gao H, Zhao YY, Yang Y, Lin ZY, Yang LR, Zhu K, Han R, Huang WW, Wang RQ, Yang LL, Wang WJ, Li L, Wang XD, Hou ZL, Liao LW, Yang L
Rejuvenation research 2021 Aug;24(4):283-293
Rejuvenation research 2021 Aug;24(4):283-293
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
Zhao Y, He L, Wang T, Zhu L, Yan N
Metabolites 2021 Aug 23;11(8)
Metabolites 2021 Aug 23;11(8)
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Japanese encephalitis virus manipulates lysosomes membrane for RNA replication and utilizes autophagy components for intracellular growth.
Xu Q, Huang L, Xing J, Zhang J, Li H, Liu L, Hu C, Liao M, Yue J, Qi W
Veterinary microbiology 2021 Apr;255:109025
Veterinary microbiology 2021 Apr;255:109025
Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma.
Cao B, Wang P, Gu L, Liu J
Oncology letters 2021 Apr;21(4):249
Oncology letters 2021 Apr;21(4):249
STING regulates BCR signaling in normal and malignant B cells.
Tang CA, Lee AC, Chang S, Xu Q, Shao A, Lo Y, Spalek WT, Pinilla-Ibarz JA, Del Valle JR, Hu CA
Cellular & molecular immunology 2021 Apr;18(4):1016-1031
Cellular & molecular immunology 2021 Apr;18(4):1016-1031
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Fu G, Lu L, Pan Z, Fan A, Yin F
Regenerative medicine 2021 Apr;16(4):359-372
Regenerative medicine 2021 Apr;16(4):359-372
Extracellular-vesicle containing miRNA-503-5p released by macrophages contributes to atherosclerosis.
Wang Y, Xu Z, Wang X, Zheng J, Peng L, Zhou Y, Song Y, Lu Z
Aging 2021 Apr 19;13(8):12239-12257
Aging 2021 Apr 19;13(8):12239-12257
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Torres-Odio S, Lei Y, Gispert S, Maletzko A, Key J, Menissy SS, Wittig I, Auburger G, West AP
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage.
Tung SL, Fanelli G, Matthews RI, Bazoer J, Letizia M, Vizcay-Barrena G, Faruqu FN, Philippeos C, Hannen R, Al-Jamal KT, Lombardi G, Smyth LA
Frontiers in cell and developmental biology 2020;8:317
Frontiers in cell and developmental biology 2020;8:317
Mechanism of Sanguinarine in Inhibiting Macrophages to Promote Metastasis and Proliferation of Lung Cancer via Modulating the Exosomes in A549 Cells.
Yu Y, Luo Y, Fang Z, Teng W, Yu Y, Tian J, Guo P, Xu R, Wu J, Li Y
OncoTargets and therapy 2020;13:8989-9003
OncoTargets and therapy 2020;13:8989-9003
Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance.
Wang X, Cheng K, Zhang G, Jia Z, Yu Y, Guo J, Hua Y, Guo F, Li X, Zou W, Sun H, Dong J, Yang Z
Frontiers in oncology 2020;10:960
Frontiers in oncology 2020;10:960
Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer.
Ding XQ, Wang ZY, Xia D, Wang RX, Pan XR, Tong JH
Frontiers in oncology 2020;10:1113
Frontiers in oncology 2020;10:1113
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
Li X, Zhang Y, Zhang M, Wang Y
Scientific reports 2020 Sep 30;10(1):16168
Scientific reports 2020 Sep 30;10(1):16168
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Xin D, Li T, Chu X, Ke H, Yu Z, Cao L, Bai X, Liu D, Wang Z
Acta biomaterialia 2020 Sep 1;113:597-613
Acta biomaterialia 2020 Sep 1;113:597-613
Insight into the proteomic profiling of exosomes secreted by human OM-MSCs reveals a new potential therapy.
Xun C, Ge L, Tang F, Wang L, Zhuo Y, Long L, Qi J, Hu L, Duan D, Chen P, Lu M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110584
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110584
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Yang D, Wang Q, Wei G, Wu J, Zhu YC, Zhu Q, Ni T, Liu X, Zhu YZ
Aging 2020 Nov 3;12(21):21423-21445
Aging 2020 Nov 3;12(21):21423-21445
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.
Song L, Liu Z, Hu HH, Yang Y, Li TY, Lin ZZ, Ye J, Chen J, Huang X, Liu DT, Zhou J, Shi Y, Zhao H, Xie C, Chen L, Song E, Lin SY, Lin SC
Nature communications 2020 Nov 17;11(1):5842
Nature communications 2020 Nov 17;11(1):5842
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Li J, Liu X, Zang S, Zhou J, Zhang F, Sun B, Qi D, Li X, Kong J, Jin D, Yang X, Luo Y, Lu Y, Lin B, Niu W, Liu T
Cancer letters 2020 Nov 1;492:71-83
Cancer letters 2020 Nov 1;492:71-83
Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8(+) T cell response in tumor.
Wang Y, Wang X, Cui X, Zhuo Y, Li H, Ha C, Xin L, Ren Y, Zhang W, Sun X, Ge L, Liu X, He J, Zhang T, Zhang K, Yao Z, Yang X, Yang J
Science advances 2020 May;6(22)
Science advances 2020 May;6(22)
Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer.
Deng Q, Fang Q, Xie B, Sun H, Bao Y, Zhou S
Aging 2020 May 6;12(9):8001-8015
Aging 2020 May 6;12(9):8001-8015
HPV + HNSCC-derived exosomal miR-9 induces macrophage M1 polarization and increases tumor radiosensitivity.
Tong F, Mao X, Zhang S, Xie H, Yan B, Wang B, Sun J, Wei L
Cancer letters 2020 May 28;478:34-44
Cancer letters 2020 May 28;478:34-44
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Gao M, Dong Z, Sun J, Liu W, Xu M, Li C, Zhu P, Yang X, Shang X, Wu Y, Liu S
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice.
Zhao F, Cheng L, Shao Q, Chen Z, Lv X, Li J, He L, Sun Y, Ji Q, Lu P, Ji Y, Ji J
Scientific reports 2020 Mar 6;10(1):4197
Scientific reports 2020 Mar 6;10(1):4197
APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin.
Uzureau S, Lecordier L, Uzureau P, Hennig D, Graversen JH, Homblé F, Mfutu PE, Oliveira Arcolino F, Ramos AR, La Rovere RM, Luyten T, Vermeersch M, Tebabi P, Dieu M, Cuypers B, Deborggraeve S, Rabant M, Legendre C, Moestrup SK, Levtchenko E, Bultynck G, Erneux C, Pérez-Morga D, Pays E
Cell reports 2020 Mar 17;30(11):3821-3836.e13
Cell reports 2020 Mar 17;30(11):3821-3836.e13
Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling.
Xu L, Faruqu FN, Liam-Or R, Abu Abed O, Li D, Venner K, Errington RJ, Summers H, Wang JT, Al-Jamal KT
Journal of extracellular vesicles 2020 Jun 19;9(1):1779458
Journal of extracellular vesicles 2020 Jun 19;9(1):1779458
The protective effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on cisplatin-damaged granulosa cells.
Zhang J, Yin H, Jiang H, Du X, Yang Z
Taiwanese journal of obstetrics & gynecology 2020 Jul;59(4):527-533
Taiwanese journal of obstetrics & gynecology 2020 Jul;59(4):527-533
Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSCs) enhances Nanog expression and provides a serum-free condition for exosome isolation.
Faruqu FN, Zhou S, Sami N, Gheidari F, Lu H, Al-Jamal KT
FASEB bioAdvances 2020 Jul;2(7):419-433
FASEB bioAdvances 2020 Jul;2(7):419-433
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Duan TL, Jiao H, He GJ, Yan YB
Cells 2020 Jan 9;9(1)
Cells 2020 Jan 9;9(1)
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
Li M, Wang J, Fu L, Lu Y, Xu J, Zhou L, Zhu H, Fang L, Feng Z, Xie T, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Li N, Luo X, Yu Q, Yang P, Chen Z, Wang X, Jiang J, Xu J, Gong Q, Eizirik DL, Zhou Z, Zhao J, Xiong F, Zhang S, Wang CY
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
Zheng Y, Zhuang MW, Han L, Zhang J, Nan ML, Zhan P, Kang D, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
Polyethylene Glycol 35 (PEG35) Modulates Exosomal Uptake and Function.
Ferrero-Andrés A, Closa D, Roselló-Catafau J, Folch-Puy E
Polymers 2020 Dec 18;12(12)
Polymers 2020 Dec 18;12(12)
Mycobacterium tuberculosis MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response.
Sun Y, Zhang W, Dong C, Xiong S
mBio 2020 Dec 1;11(6)
mBio 2020 Dec 1;11(6)
SCYL1 arginine methylation by PRMT1 is essential for neurite outgrowth via Golgi morphogenesis.
Amano G, Matsuzaki S, Mori Y, Miyoshi K, Han S, Shikada S, Takamura H, Yoshimura T, Katayama T
Molecular biology of the cell 2020 Aug 15;31(18):1963-1973
Molecular biology of the cell 2020 Aug 15;31(18):1963-1973
USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy.
Niu K, Fang H, Chen Z, Zhu Y, Tan Q, Wei D, Li Y, Balajee AS, Zhao Y
Autophagy 2020 Apr;16(4):724-734
Autophagy 2020 Apr;16(4):724-734
Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress.
Zheng D, Chen Y, Ai S, Zhang R, Gao Z, Liang C, Cao L, Chen Y, Hong Z, Shi Y, Wang L, Li X, Yang Z
Research (Washington, D.C.) 2019;2019:4803624
Research (Washington, D.C.) 2019;2019:4803624
Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2.
Bersuker K, Olzmann JA
Methods in molecular biology (Clifton, N.J.) 2019;2008:57-72
Methods in molecular biology (Clifton, N.J.) 2019;2008:57-72
Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation.
Yan H, Gao Y, Ding Q, Liu J, Li Y, Jin M, Xu H, Ma S, Wang X, Zeng W, Chen Y
International journal of biological sciences 2019;15(7):1368-1382
International journal of biological sciences 2019;15(7):1368-1382
Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.
Lin Y, Liang A, He Y, Li Z, Li Z, Wang G, Sun F
Molecular reproduction and development 2019 Sep;86(9):1094-1105
Molecular reproduction and development 2019 Sep;86(9):1094-1105
Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress.
Merriman C, Fu D
The Journal of biological chemistry 2019 Nov 8;294(45):16992-17006
The Journal of biological chemistry 2019 Nov 8;294(45):16992-17006
Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway.
Cui Y, Wang Y, Liu G
International journal of molecular medicine 2019 May;43(5):2015-2023
International journal of molecular medicine 2019 May;43(5):2015-2023
Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia.
McKay EC, Beck JS, Khoo SK, Dykema KJ, Cottingham SL, Winn ME, Paulson HL, Lieberman AP, Counts SE
Journal of neuropathology and experimental neurology 2019 May 1;78(5):436-452
Journal of neuropathology and experimental neurology 2019 May 1;78(5):436-452
Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection.
Wang J, Teng Y, Zhao G, Li F, Hou A, Sun B, Kong W, Gao F, Cai L, Jiang C
International journal of molecular sciences 2019 Mar 27;20(7)
International journal of molecular sciences 2019 Mar 27;20(7)
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Du Y, Hu H, Pei X, Du K, Wei T
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Two novel ANK1 loss-of-function mutations in Chinese families with hereditary spherocytosis.
Hao L, Li S, Ma D, Chen S, Zhang B, Xiao D, Zhang J, Jiang N, Jiang S, Ma J
Journal of cellular and molecular medicine 2019 Jun;23(6):4454-4463
Journal of cellular and molecular medicine 2019 Jun;23(6):4454-4463
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
An H, Ordureau A, Paulo JA, Shoemaker CJ, Denic V, Harper JW
Molecular cell 2019 Jun 6;74(5):891-908.e10
Molecular cell 2019 Jun 6;74(5):891-908.e10
Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression.
Bonenfant G, Williams N, Netzband R, Schwarz MC, Evans MJ, Pager CT
Journal of virology 2019 Jun 15;93(12)
Journal of virology 2019 Jun 15;93(12)
Microglia as modulators of exosomal alpha-synuclein transmission.
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T
Cell death & disease 2019 Feb 20;10(3):174
Cell death & disease 2019 Feb 20;10(3):174
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Shi J, Hu X, Guo Y, Wang L, Ji J, Li J, Zhang ZR
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway.
Wang S, Su X, Xu M, Xiao X, Li X, Li H, Keating A, Zhao RC
Stem cell research & therapy 2019 Apr 11;10(1):117
Stem cell research & therapy 2019 Apr 11;10(1):117
Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways.
Song M, Han L, Chen FF, Wang D, Wang F, Zhang L, Wang ZH, Zhong M, Tang MX, Zhang W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(4):1416-1432
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(4):1416-1432
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Li M, Du W, Zhou M, Zheng L, Song E, Hou J
Biophysics reports 2018;4(6):329-338
Biophysics reports 2018;4(6):329-338
Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.
Zhou X, Yan T, Huang C, Xu Z, Wang L, Jiang E, Wang H, Chen Y, Liu K, Shao Z, Shang Z
Journal of experimental & clinical cancer research : CR 2018 Oct 3;37(1):242
Journal of experimental & clinical cancer research : CR 2018 Oct 3;37(1):242
In Vivo Tracking of Multiple Tumor Exosomes Labeled by Phospholipid-Based Bioorthogonal Conjugation.
Zhang P, Dong B, Zeng E, Wang F, Jiang Y, Li D, Liu D
Analytical chemistry 2018 Oct 2;90(19):11273-11279
Analytical chemistry 2018 Oct 2;90(19):11273-11279
Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.
Zhao N, Mi L, Zhang X, Xu M, Yu H, Liu Z, Liu X, Guan G, Gao W, Wang J
Journal of molecular and cellular cardiology 2018 May;118:36-45
Journal of molecular and cellular cardiology 2018 May;118:36-45
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.
Li TY, Song L, Sun Y, Li J, Yi C, Lam SM, Xu D, Zhou L, Li X, Yang Y, Zhang CS, Xie C, Huang X, Shui G, Lin SY, Reue K, Lin SC
Nature communications 2018 May 15;9(1):1916
Nature communications 2018 May 15;9(1):1916
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
Xin X, Wang H, Han L, Wang M, Fang H, Hao Y, Li J, Zhang H, Zheng C, Shen C
Journal of virology 2018 May 1;92(9)
Journal of virology 2018 May 1;92(9)
A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.
Huang EY, To M, Tran E, Dionisio LTA, Cho HJ, Baney KLM, Pataki CI, Olzmann JA
Molecular biology of the cell 2018 May 1;29(9):1021-1030
Molecular biology of the cell 2018 May 1;29(9):1021-1030
A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation.
Tesi B, Rascon J, Chiang SCC, Burnyte B, Löfstedt A, Fasth A, Heizmann M, Juozapaite S, Kiudeliene R, Kvedaraite E, Miseviciene V, Muleviciene A, Müller ML, Nordenskjöld M, Matuzeviciene R, Samaitiene R, Speckmann C, Stankeviciene S, Zekas V, Voss M, Ehl S, Vaiciene-Magistris N, Henter JI, Meeths M, Bryceson YT
The Journal of allergy and clinical immunology 2018 Jul;142(1):317-321.e8
The Journal of allergy and clinical immunology 2018 Jul;142(1):317-321.e8
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
Ganji R, Mukkavalli S, Somanji F, Raman M
Molecular and cellular biology 2018 Jul 1;38(13)
Molecular and cellular biology 2018 Jul 1;38(13)
A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.
Bersuker K, Peterson CWH, To M, Sahl SJ, Savikhin V, Grossman EA, Nomura DK, Olzmann JA
Developmental cell 2018 Jan 8;44(1):97-112.e7
Developmental cell 2018 Jan 8;44(1):97-112.e7
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Luo H, Jiang M, Lian G, Liu Q, Shi M, Li TY, Song L, Ye J, He Y, Yao L, Zhang C, Lin ZZ, Zhang CS, Zhao TJ, Jia WP, Li P, Lin SY, Lin SC
Cell metabolism 2018 Apr 3;27(4):843-853.e6
Cell metabolism 2018 Apr 3;27(4):843-853.e6
Protein kinase D at the Golgi controls NLRP3 inflammasome activation.
Zhang Z, Meszaros G, He WT, Xu Y, de Fatima Magliarelli H, Mailly L, Mihlan M, Liu Y, Puig Gámez M, Goginashvili A, Pasquier A, Bielska O, Neven B, Quartier P, Aebersold R, Baumert TF, Georgel P, Han J, Ricci R
The Journal of experimental medicine 2017 Sep 4;214(9):2671-2693
The Journal of experimental medicine 2017 Sep 4;214(9):2671-2693
Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis.
Komaki M, Numata Y, Morioka C, Honda I, Tooi M, Yokoyama N, Ayame H, Iwasaki K, Taki A, Oshima N, Morita I
Stem cell research & therapy 2017 Oct 3;8(1):219
Stem cell research & therapy 2017 Oct 3;8(1):219
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Liu Z, Wang Y, Wang Y, Dong W, Xia X, Song E, Song Y
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.
Li P, Du J, Goodier JL, Hou J, Kang J, Kazazian HH Jr, Zhao K, Yu XF
Nucleic acids research 2017 May 5;45(8):4619-4631
Nucleic acids research 2017 May 5;45(8):4619-4631
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Bonjoch L, Gironella M, Iovanna JL, Closa D
Scientific reports 2017 Jun 9;7(1):3143
Scientific reports 2017 Jun 9;7(1):3143
Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.
De Franco E, Flanagan SE, Yagi T, Abreu D, Mahadevan J, Johnson MB, Jones G, Acosta F, Mulaudzi M, Lek N, Oh V, Petz O, Caswell R, Ellard S, Urano F, Hattersley AT
Diabetes 2017 Jul;66(7):2044-2053
Diabetes 2017 Jul;66(7):2044-2053
DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.
Ding J, Shao L, Yao Y, Tong X, Liu H, Yue S, Xie L, Cheng SY
Scientific reports 2017 Jul 13;7(1):5296
Scientific reports 2017 Jul 13;7(1):5296
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.
Sasai M, Sakaguchi N, Ma JS, Nakamura S, Kawabata T, Bando H, Lee Y, Saitoh T, Akira S, Iwasaki A, Standley DM, Yoshimori T, Yamamoto M
Nature immunology 2017 Aug;18(8):899-910
Nature immunology 2017 Aug;18(8):899-910
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
Bonjoch L, Casas V, Carrascal M, Closa D
The Journal of pathology 2016 Oct;240(2):235-45
The Journal of pathology 2016 Oct;240(2):235-45
Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.
Zhou Y, Xiong L, Zhang Y, Yu R, Jiang X, Xu G
Journal of proteomics 2016 Oct 4;148:94-104
Journal of proteomics 2016 Oct 4;148:94-104
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Lin JJ, Wang RY, Chen JC, Chiu CC, Liao MH, Wu YJ
International journal of molecular sciences 2016 Oct 27;17(11)
International journal of molecular sciences 2016 Oct 27;17(11)
Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector.
Dong N, Niu M, Hu L, Yao Q, Zhou R, Shao F
Nature microbiology 2016 Dec 12;2:16236
Nature microbiology 2016 Dec 12;2:16236
Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer.
Wang X, Xu C, Hua Y, Sun L, Cheng K, Jia Z, Han Y, Dong J, Cui Y, Yang Z
Journal of experimental & clinical cancer research : CR 2016 Dec 1;35(1):186
Journal of experimental & clinical cancer research : CR 2016 Dec 1;35(1):186
Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.
Yang XX, Xu F, Wang D, Yang ZW, Tan HR, Shang MY, Wang X, Cai SQ
Journal of chromatography. A 2015 Sep 25;1413:33-46
Journal of chromatography. A 2015 Sep 25;1413:33-46
Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.
Jokinen R, Lahtinen T, Marttinen P, Myöhänen M, Ruotsalainen P, Yeung N, Shvetsova A, Kastaniotis AJ, Hiltunen JK, Öhman T, Nyman TA, Weiler H, Battersby BJ
Genetics 2015 May;200(1):221-35
Genetics 2015 May;200(1):221-35
IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.
Zhu X, He Z, Yuan J, Wen W, Huang X, Hu Y, Lin C, Pan J, Li R, Deng H, Liao S, Zhou R, Wu J, Li J, Li M
Cellular microbiology 2015 Jan;17(1):105-18
Cellular microbiology 2015 Jan;17(1):105-18
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Mao Q, Xie Z, Wang X, Chen W, Ren M, Shang M, Lei H, Tian Y, Li S, Liang P, Chen T, Liang C, Xu J, Li X, Huang Y, Yu X
Parasitology research 2015 Feb;114(2):659-70
Parasitology research 2015 Feb;114(2):659-70
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, Chen F, Yang C, Zhou Z, Su SS, Zheng X, Zhang Z, Zhong CQ, Wan H, Xiao M, Lin X, Feng XH, Han J
Nature cell biology 2015 Apr;17(4):434-44
Nature cell biology 2015 Apr;17(4):434-44
PolyC-binding protein 1 interacts with 5'-untranslated region of enterovirus 71 RNA in membrane-associated complex to facilitate viral replication.
Luo Z, Dong X, Li Y, Zhang Q, Kim C, Song Y, Kang L, Liu Y, Wu K, Wu J
PloS one 2014;9(1):e87491
PloS one 2014;9(1):e87491
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Ota K, Obayashi M, Ozaki K, Ichinose S, Kakita A, Tada M, Takahashi H, Ando N, Eishi Y, Mizusawa H, Ishikawa K
Acta neuropathologica communications 2014 Sep 11;2:136
Acta neuropathologica communications 2014 Sep 11;2:136
Rab18 and a Rab18 GEF complex are required for normal ER structure.
Gerondopoulos A, Bastos RN, Yoshimura S, Anderson R, Carpanini S, Aligianis I, Handley MT, Barr FA
The Journal of cell biology 2014 Jun 9;205(5):707-20
The Journal of cell biology 2014 Jun 9;205(5):707-20
Reduced expression of members of the mhc-i antigen processing machinery in ethnic Uighur women with cervical cancer in the Xinjiang region of China.
Haimiti A, Hailiman Y, Gulina A, Du J, Hao Z, Rong XL, Zainuer A, Qin W, Lalai S
Current oncology (Toronto, Ont.) 2014 Feb;21(1):e67-74
Current oncology (Toronto, Ont.) 2014 Feb;21(1):e67-74
ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.
Tan YL, Genereux JC, Pankow S, Aerts JM, Yates JR 3rd, Kelly JW
Chemistry & biology 2014 Aug 14;21(8):967-76
Chemistry & biology 2014 Aug 14;21(8):967-76
Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis.
Shang Y, Wang F, Bai C, Huang Y, Zhao LJ, Yao XP, Li Q, Sun SH
Chinese medical journal 2011 Jan;124(1):38-44
Chinese medical journal 2011 Jan;124(1):38-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 10427-2-AP(CANX antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of A431 cells, using CANX antibody 10427-2-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG(green).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10427-2-AP(CANX antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10427-2-AP(CANX antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Calnexin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Calnexin. This antibody recognizes human,mouse,rat antigen. The Calnexin antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.
