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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [120]
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- Product number
- 66903-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- Calnexin antibody
- Antibody type
- Monoclonal
- Description
- Calnexin antibody (Cat. #66903-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2A2C6
- Vial size
- 20ul, 150ul
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Cytoplasmic RNase III Drosha controls lipogenesis by noncanonical regulation of SREBP1.
Novel Dual-Pharmacophore TrxR Inhibitors Integrating Ferroptosis and Antitumor Immunity: A Closed-Loop Strategy for TIME Remodeling.
A Nanobody-Based Toolbox to Probe ApoE4 in the Secretory Pathway and Cytosol.
A dual role for ER-Golgi cargo receptor LMAN1 in supporting CSFV replication and restraining RLR signaling.
Fibroblast-derived exosomes induce macrophage pyroptosis to mediate orthodontic bone remodeling through the mtDNA/NLRP3 axis.
A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication.
Exosomal miRNA-218-5p derived from low-passage dermal papilla cells modulates hair follicle growth and development.
Systemic LINE-1 RNA in Plasma Extracellular Vesicles Drives Neuroinflammation and Cognitive Dysfunction via cGAS-STING Pathway in Aging.
Precise subcellular organelle-targeted analyses of hepatotoxicity of Polygonum multiflorum.
Isobavachalcone ameliorates TNBS-induced Crohn's disease-like colitis via GPR84-PI3K-AKT axis.
Hypoxia-conditioned BMSC exosomes improve short-term spinal cord injury outcomes via the miR-615-3p/PDE4C-mediated cAMP/PKA pathway.
Dental Pulp Stem Cell-Derived Intracellular Vesicles Promote Cartilage Regeneration and Alleviate Pain in Temporomandibular Joint Osteoarthritis.
Caveolin-1 drives immunosuppression in esophageal squamous cell carcinoma by enhancing exosome secretion and macrophage M2 polarization via inhibition of MVB autophagic degradation.
Non-canonical proteolytic activation of RNase L by SARS-CoV-2 3CL(pro) offsets inactivation of OAS1 p46 antiviral signaling.
UHRF1-mediated DNA 5-mC modification drives super-enhancer redistribution and impedes osteogenesis via TGM2-regulated autophagic flux in senile osteoporosis.
Bioengineered Anti-PD-L1 Functionalized Nanoplatform for Targeted Delivery and Tumor Immune Reprogramming Against Colorectal Cancer.
Proteomic Landscape of Small Extracellular Vesicles Derived From Gastric Juice and Identified TFF2 as a Specific Biomarker.
Safety, Efficacy and Bio-Distribution Analysis of Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells for Effective Treatment of Bronchopulmonary Dysplasia by Intranasal Administration in Mice Model.
Tumor-derived exosome-based microRNA-206 delivery system as dual modulators of the immune microenvironment and gut microbiota for colorectal cancer therapy.
Legionella pneumophila Effector Protein LegU1 Mediates the Ubiquitination of Endoplasmic Reticulum Chaperone BiP.
Engineered extracellular vesicles for targeted FGF20 delivery enhance neuroplasticity and functional recovery in ischemic stroke.
Tenascin-C-enriched extracellular vesicles contribute to osteosarcoma progression via regulation of the angiotensin II receptor type 1 pathway.
Goblet cell-expressed microprotein FXYD3 determines gut homeostasis by maintaining mucus barrier integrity.
Microfluidics-based label-free SERS profiling of exosomes with machine learning for osteosarcoma diagnosis.
Regulation of N-Glycosylation of CDNF on Its Protein Stability and Function in Hypoxia/Reoxygenation Model of H9C2 Cells.
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
Choline Phosphate Surface-Activated 3D-Printed Porous Titanium Scaffold Combined with Stem Cell Exosomes for Enhancing Bone Defects Repair.
Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis.
DSTYK phosphorylates STING at late endosomes to promote STING signaling.
Adipocyte-derived glutathione promotes obesity-related breast cancer by regulating the SCARB2-ARF1-mTORC1 complex.
MDA5 protein mediating persistent ER stress/unfolded protein response contributes to endothelial-mesenchymal-transition of lung microvascular endothelial cell in dermatomyositis.
Repurposing oxiconazole to inhibit STING trafficking via OSBP and alleviate autoimmune pathology in Trex1(-/-) mice.
Dynamic regulation of the COPII interactome and collagen trafficking by site-specific glycosylation of Sec24D.
Transdermal psoriasis treatment inspired by tumor microenvironment-mediated immunomodulation and advanced by exosomal engineering.
Exploring Exosome Contributions to Gouty Arthritis: A Proteomics and Experimental Study.
Vesicle-associated membrane protein 5 is an intrinsic defense factor for embryonic stem cells against coronaviruses.
Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression.
Extracellular vesicle-enriched secretome of adipose-derived stem cells upregulates clusterin to alleviate doxorubicin-induced apoptosis in cardiomyocytes.
HIF-1α/BNIP3-Mediated Endoplasmic Reticulum Degradation via Autophagy Protects Against Ischemia Reperfusion-Induced Acute Kidney Injury.
GSTK1 and RETREG1/FAM134B-mediated reticulophagy attenuates tubular injury in diabetic nephropathy through endoplasmic reticulum stress and apoptosis.
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity.
Metformin Ameliorates Early Brain Injury After Subarachnoid Hemorrhage Via Improving Endoplasmic Reticulum Stress and Mitochondrial Stress-Mediated Ca(2+) Imbalance.
Cholesterol induced-mitochondrial calcium dysregulation facilitates atherosclerosis by promoting lipid accumulation in vascular smooth muscle cells.
RHOA regulates mitochondria-ER contact sites through modulation of the VAPB/PTPIP51 tether.
Synergistic chemoimmunotherapy using pirarubicin-loaded tumor-derived extracellular vesicles for triple-negative breast cancer (TNBC).
Adhesive hydrogel based on Konjac Glucomannan (KGM) loaded with siACTC1-exosomes for enhanced post-surgical keloid treatment.
Stereo-cell: Spatial enhanced-resolution single-cell sequencing with high-density DNA nanoball-patterned arrays.
Cdk5rap3-mediated regulation of lysosomal and ER membrane proteins is pivotal for the survival and function of pancreatic acinar cells.
Lymph node-targeted delivery of Lonicera japonica thunb. polysaccharides for enhancing antitumor immunotherapy.
TMED9 coordinates the clearance of misfolded GPI-anchored proteins out of the ER and into the Golgi.
Cytochrome P450 2E1 aggravates DXR-induced myocardial injury through imbalanced mitochondrial OPA1.
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis.
Physical exercise-induced circAnks1b upregulation promotes protective endoplasmic reticulum stress and suppresses apoptosis via miR-130b-5p/Pak2 signaling in an ischemic stroke model.
The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress.
Proteomic Profiling of Unannotated Microproteins in Human Placenta Reveals XRCC6P1 as a Potential Negative Regulator of Translation.
Development of a Signal-integrating Reporter to Monitor Mitochondria-ER Contacts.
Dihydroartemisinin inhibits ATP6 activity, reduces energy metabolism of hepatocellular carcinoma cells, promotes apoptosis and inhibits metastasis via CANX.
Plasma-derived exosome miR-10a-5p promotes premature ovarian failure by target BDNF via the TrkB/Akt/mTOR signaling pathway.
Selective regulation of aspartyl intramembrane protease activity by calnexin.
Induction of tau pathology and motor dysfunction in mice by urinary exosomes from progressive supranuclear palsy patients.
Circulating extracellular vesicles from severe COVID-19 patients induce lung inflammation.
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
AGR2-mediated unconventional secretion of 14-3-3ε and α-actinin-4, responsive to ER stress and autophagy, drives chemotaxis in canine mammary tumor cells.
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
Exosomes From IgE-Stimulated Mast Cells Aggravate Asthma-Mediated Atherosclerosis Through circRNA CDR1as-Mediated Endothelial Cell Dysfunction in Mice.
The HRI branch of the integrated stress response selectively triggers mitophagy.
NSP6 inhibits the production of ACE2-containing exosomes to promote SARS-CoV-2 infectivity.
Chemoproteomics enables identification of coatomer subunit zeta-1 targeted by a small molecule for enterovirus A71 inhibition.
AS1411 binds to nucleolin via its parallel structure and disrupts the exos-miRNA-27a-mediated reciprocal activation loop between glioma and astrocytes.
Mitochondrial translation failure represses cholesterol gene expression via Pyk2-Gsk3β-Srebp2 axis.
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Targeting KDM4 family epigenetically triggers antitumour immunity via enhancing tumour-intrinsic innate sensing and immunogenicity.
Development of a signal-integrating reporter to monitor mitochondria-ER contacts.
Exosomes from adipose-derived stem cells overexpressing microRNA-671-3p promote fat graft angiogenesis and adipogenic differentiation.
Modulation of the unfolded protein response by white spot syndrome virus via wsv406 targeting BiP to facilitate viral replication.
A roadmap for ribosome assembly in human mitochondria.
The SLE-associated TREX1-P212fs mutation disrupts ER association leading to type I interferonopathy.
Carnosic Acid: A Novel Selective Inhibitor of ERAP1 by Direct Binding and Its Modulation of Antigen Processing and Presentation.
Targeted treatment of rat AKI induced by rhabdomyolysis using BMSC derived magnetic exosomes and its mechanism.
Two-Step Enrichment Facilitates Background Reduction for Proteomic Analysis of Lysosomes.
Deletion of Emc1 in photoreceptor cells causes retinal degeneration in mice.
DWL-4-140: A allene small molecule targeting STING that alleviates lupus-like phenotype in Trex1(-/-) mice.
Dysregulation of MicroRNAs Derived from Plasma Extracellular Vesicles in Schizoaffective Disorder.
Hsa_circ_0041150 serves as a novel biomarker for monitoring chemotherapy resistance in small cell lung cancer patients treated with a first-line chemotherapy regimen.
ATAD1 inhibits hepatitis C virus infection by removing the viral TA-protein NS5B from mitochondria.
Deficiency of RAB39B Activates ER Stress-Induced Pro-apoptotic Pathway and Causes Mitochondrial Dysfunction and Oxidative Stress in Dopaminergic Neurons by Impairing Autophagy and Upregulating α-Synuclein.
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation.
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Targeting ATAD3A-PINK1-mitophagy axis overcomes chemoimmunotherapy resistance by redirecting PD-L1 to mitochondria.
Multi-Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins.
Charcot-Marie-Tooth-1A and sciatic nerve crush rat models: insights from proteomics.
Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1.
Extracellular vesicles encapsulated with caspase-1 inhibitor ameliorate experimental autoimmune myasthenia gravis through targeting macrophages.
Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.
Long Noncoding RNA SBF2-AS1 Promotes Abdominal Aortic Aneurysm Formation through the miRNA-520f-3p/SMARCD1 Axis.
Safety and biodistribution of exosomes derived from human induced pluripotent stem cells.
Substitution of SERCA2 Cys(674) aggravates cardiac fibrosis by promoting the transformation of cardiac fibroblasts to cardiac myofibroblasts.
A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis.
Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo.
Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis.
Porcine deltacoronavirus accessory protein NS7a possesses the functional characteristics of a viroporin.
Blood plasma derived extracellular vesicles (BEVs): particle purification liquid chromatography (PPLC) and proteomic analysis reveals BEVs as a potential minimally invasive tool for predicting response to breast cancer treatment.
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
Differential expression of exosomal microRNAs in fresh and senescent apheresis platelet concentrates.
A new integrated method for tissue extracellular vesicle enrichment and proteome profiling.
The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6.
Cellular ESCRT components are recruited to regulate the endocytic trafficking and RNA replication compartment assembly during classical swine fever virus infection.
Construction and analysis of expression profile of exosomal lncRNAs in pleural effusion in lung adenocarcinoma.
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
Osteosarcoma Cell-Derived Small Extracellular Vesicles Enhance Osteoclastogenesis and Bone Resorption Through Transferring MicroRNA-19a-3p.
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells.
Exosome-Delivered LncHEIH Promotes Gastric Cancer Progression by Upregulating EZH2 and Stimulating Methylation of the GSDME Promoter.
ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy.
Cui C, Huo Q, Ran S, Wang W, Wei H, Peng J
Journal of advanced research 2026 May;83:269-285
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Cytoplasmic RNase III Drosha controls lipogenesis by noncanonical regulation of SREBP1.
Nie T, Lu J, Dong D, Gao Q, Ren D, Huang L, Zhao S, Zhu L, Shi X, Du X, Mao Z, Yang Q
Molecular cell 2026 May 7;86(9):1762-1779.e8
Molecular cell 2026 May 7;86(9):1762-1779.e8
Novel Dual-Pharmacophore TrxR Inhibitors Integrating Ferroptosis and Antitumor Immunity: A Closed-Loop Strategy for TIME Remodeling.
Xu Z, Yang Z, Lv L, Yang J, Liu W
Journal of medicinal chemistry 2026 May 14;69(9):10811-10827
Journal of medicinal chemistry 2026 May 14;69(9):10811-10827
A Nanobody-Based Toolbox to Probe ApoE4 in the Secretory Pathway and Cytosol.
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Cells 2026 Mar 6;15(5)
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A dual role for ER-Golgi cargo receptor LMAN1 in supporting CSFV replication and restraining RLR signaling.
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Journal of virology 2026 Mar 24;100(3):e0006926
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Fibroblast-derived exosomes induce macrophage pyroptosis to mediate orthodontic bone remodeling through the mtDNA/NLRP3 axis.
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Journal of nanobiotechnology 2026 Mar 14;24(1)
Journal of nanobiotechnology 2026 Mar 14;24(1)
A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication.
Rajasekharan S, Barragan Torres VA, Pinheiro Gomes YC, Wilken L, Overhoff K, Lin YC, Patten SA, Watanabe S, Chatel-Chaix L, Scaturro P
Nature communications 2026 Mar 13;17(1)
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Exosomal miRNA-218-5p derived from low-passage dermal papilla cells modulates hair follicle growth and development.
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Non-coding RNA research 2026 Jun;18:1-11
Non-coding RNA research 2026 Jun;18:1-11
Systemic LINE-1 RNA in Plasma Extracellular Vesicles Drives Neuroinflammation and Cognitive Dysfunction via cGAS-STING Pathway in Aging.
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Aging cell 2026 Jan;25(1):e70350
Aging cell 2026 Jan;25(1):e70350
Precise subcellular organelle-targeted analyses of hepatotoxicity of Polygonum multiflorum.
Li Y, Duan S, Zhang Y, Liu R, Sun R, Wu J, Ma Z, Li X
Chinese herbal medicines 2026 Jan;18(1):153-166
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Isobavachalcone ameliorates TNBS-induced Crohn's disease-like colitis via GPR84-PI3K-AKT axis.
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Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120575
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120575
Hypoxia-conditioned BMSC exosomes improve short-term spinal cord injury outcomes via the miR-615-3p/PDE4C-mediated cAMP/PKA pathway.
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Stem cell research & therapy 2026 Jan 12;17(1):78
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Dental Pulp Stem Cell-Derived Intracellular Vesicles Promote Cartilage Regeneration and Alleviate Pain in Temporomandibular Joint Osteoarthritis.
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International dental journal 2026 Feb;76(1):103974
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Caveolin-1 drives immunosuppression in esophageal squamous cell carcinoma by enhancing exosome secretion and macrophage M2 polarization via inhibition of MVB autophagic degradation.
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Journal of translational medicine 2026 Feb 4;24(1)
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Non-canonical proteolytic activation of RNase L by SARS-CoV-2 3CL(pro) offsets inactivation of OAS1 p46 antiviral signaling.
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Cell reports 2026 Apr 17;45(4):117257
Cell reports 2026 Apr 17;45(4):117257
UHRF1-mediated DNA 5-mC modification drives super-enhancer redistribution and impedes osteogenesis via TGM2-regulated autophagic flux in senile osteoporosis.
Pang P, Chen J, Li Q, Su Z, Lin J, Zeng Y, Zhang W, Xiao Z, Chen Z, Liu Z, Lin Y, Zheng G, Yu W, Xie Z
Journal of advanced research 2026 Apr 17;
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Bioengineered Anti-PD-L1 Functionalized Nanoplatform for Targeted Delivery and Tumor Immune Reprogramming Against Colorectal Cancer.
Liu M, Ma X, Zhou R, Yang X, Zhou Y, Ma B, Su C, Duan X
Biomaterials research 2025;29:0284
Biomaterials research 2025;29:0284
Proteomic Landscape of Small Extracellular Vesicles Derived From Gastric Juice and Identified TFF2 as a Specific Biomarker.
Fan R, Wu K, Yang J, Zhu B, Jiang T, Liu Y, Yuan B, Liu L, Sun Y, Sun X, Liu L, Luo W, Zhou C, Guo Y, Liu L
International journal of nanomedicine 2025;20:6929-6948
International journal of nanomedicine 2025;20:6929-6948
Safety, Efficacy and Bio-Distribution Analysis of Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells for Effective Treatment of Bronchopulmonary Dysplasia by Intranasal Administration in Mice Model.
Xu W, Jieda X, Wu Y, Du F, Ma L, Luo L, Liu D, Guo L, Liu J, Dong W
International journal of nanomedicine 2025;20:2521-2553
International journal of nanomedicine 2025;20:2521-2553
Tumor-derived exosome-based microRNA-206 delivery system as dual modulators of the immune microenvironment and gut microbiota for colorectal cancer therapy.
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International journal of biological macromolecules 2025 Sep;321(Pt 4):146489
International journal of biological macromolecules 2025 Sep;321(Pt 4):146489
Legionella pneumophila Effector Protein LegU1 Mediates the Ubiquitination of Endoplasmic Reticulum Chaperone BiP.
Zhao B, He S, Huang M, Lu Y, Ge Z
Journal of microbiology and biotechnology 2025 Oct 28;35:e2507056
Journal of microbiology and biotechnology 2025 Oct 28;35:e2507056
Engineered extracellular vesicles for targeted FGF20 delivery enhance neuroplasticity and functional recovery in ischemic stroke.
Guo S, Wang Z, Shi R, Huang P, Fang Y, Chen S, Huang M, Hu J, Lu Y, Xu X, Zou Y, Ruan L, Li X, Lin L, Wang X
Journal of controlled release : official journal of the Controlled Release Society 2025 Oct 10;386:114080
Journal of controlled release : official journal of the Controlled Release Society 2025 Oct 10;386:114080
Tenascin-C-enriched extracellular vesicles contribute to osteosarcoma progression via regulation of the angiotensin II receptor type 1 pathway.
Wang L, Liu K, Lyu L, Yin Z
Journal of molecular histology 2025 Nov 4;56(6):366
Journal of molecular histology 2025 Nov 4;56(6):366
Goblet cell-expressed microprotein FXYD3 determines gut homeostasis by maintaining mucus barrier integrity.
Yang W, Xue Y, Zhu P, Jiang Z, He R, Tian H, Wang T, Xiao P, Lian W, Cao Q, Gan YH, Lai L, Wang Q
Cell reports 2025 Nov 25;44(11):116502
Cell reports 2025 Nov 25;44(11):116502
Microfluidics-based label-free SERS profiling of exosomes with machine learning for osteosarcoma diagnosis.
Jin Y, Zhang J, Wu X, Qu C, Fang X, Yang Y, Yuan Y, Liu H, Han Z
Talanta 2025 Nov 1;294:128276
Talanta 2025 Nov 1;294:128276
Regulation of N-Glycosylation of CDNF on Its Protein Stability and Function in Hypoxia/Reoxygenation Model of H9C2 Cells.
Huang Q, Dong H, Jia W, Ren Y, Li W, Zhong L, Gong L, Yang J
Cell biology international 2025 May;49(5):472-483
Cell biology international 2025 May;49(5):472-483
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
Shen H, Xie Y, Wang Y, Xie Y, Wang Y, Su Z, Zhao L, Yao S, Cao X, Liang J, Long J, Zhong R, Tang J, Wang S, Zhang L, Wang X, Stork B, Cui L, Wu W
Autophagy 2025 May;21(5):1096-1115
Autophagy 2025 May;21(5):1096-1115
Choline Phosphate Surface-Activated 3D-Printed Porous Titanium Scaffold Combined with Stem Cell Exosomes for Enhancing Bone Defects Repair.
Cui X, Li J, Wang Y, Sun T, Weng J, Li Z, Li J, Chen X
ACS applied materials & interfaces 2025 May 14;17(19):27788-27805
ACS applied materials & interfaces 2025 May 14;17(19):27788-27805
Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis.
Li J, Zhao B, Yu Y, Bao Z, Zheng F, Cai J, Chen Y, Wu X
International journal of biological macromolecules 2025 Mar;295:139292
International journal of biological macromolecules 2025 Mar;295:139292
DSTYK phosphorylates STING at late endosomes to promote STING signaling.
Dong H, Zhang H, Song P, Hu Y, Chen D
EMBO reports 2025 Mar;26(6):1620-1646
EMBO reports 2025 Mar;26(6):1620-1646
Adipocyte-derived glutathione promotes obesity-related breast cancer by regulating the SCARB2-ARF1-mTORC1 complex.
Zhao C, Zhang T, Xue ST, Zhang P, Wang F, Li Y, Liu Y, Zhao L, Wu J, Yan Y, Mao X, Chen Y, Yuan J, Li Z, Li K
Cell metabolism 2025 Mar 4;37(3):692-707.e9
Cell metabolism 2025 Mar 4;37(3):692-707.e9
MDA5 protein mediating persistent ER stress/unfolded protein response contributes to endothelial-mesenchymal-transition of lung microvascular endothelial cell in dermatomyositis.
Zhao LQ, Yang XQ, Niu Q, Feng X, Zhang HD, Ye SY, Jiang LJ, Yu F, Ye H, Ma WL
Cell communication and signaling : CCS 2025 Mar 23;23(1):149
Cell communication and signaling : CCS 2025 Mar 23;23(1):149
Repurposing oxiconazole to inhibit STING trafficking via OSBP and alleviate autoimmune pathology in Trex1(-/-) mice.
Luo H, Cai Y, Shi H, Ma L, Zhang S, Yung KKL, Zhou P
International immunopharmacology 2025 Jun 5;157:114742
International immunopharmacology 2025 Jun 5;157:114742
Dynamic regulation of the COPII interactome and collagen trafficking by site-specific glycosylation of Sec24D.
Hirata T, Choudhary D, Bisnett BJ, Soderblom EJ, Knapik EW, Boyce M
bioRxiv : the preprint server for biology 2025 Jun 13;
bioRxiv : the preprint server for biology 2025 Jun 13;
Transdermal psoriasis treatment inspired by tumor microenvironment-mediated immunomodulation and advanced by exosomal engineering.
Yang J, Zhu J, Lu S, Qin H, Zhou W
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113664
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113664
Exploring Exosome Contributions to Gouty Arthritis: A Proteomics and Experimental Study.
Lu C, Yang X, Wang X, Wang Y, Zhang B, Lin Z
International journal of molecular sciences 2025 Jun 1;26(11)
International journal of molecular sciences 2025 Jun 1;26(11)
Vesicle-associated membrane protein 5 is an intrinsic defense factor for embryonic stem cells against coronaviruses.
Dong H, Pan Z, Jiao P, Ye F, Peng Q, Yu Y, Lai X, Li H, Guan Z, Deng J, Shen T, Tan W, Shi Y, Ding Q, Luo J, Li T, Zhuang H, Xiang K
Nature communications 2025 Jul 7;16(1):6241
Nature communications 2025 Jul 7;16(1):6241
Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression.
Zhou J, Ma W, Zhou R, Ma D, Liu C, Wang F, Yuan L, Xu L, Wang C, Li Q
International immunopharmacology 2025 Jul 28;160:114955
International immunopharmacology 2025 Jul 28;160:114955
Extracellular vesicle-enriched secretome of adipose-derived stem cells upregulates clusterin to alleviate doxorubicin-induced apoptosis in cardiomyocytes.
Hsu WT, Kobuchi S, Chien TR, Chen IC, Hamada S, Tsujimoto M, Tsai IL, Wong YS, Tung KH, He YZ
Biology direct 2025 Jul 16;20(1):84
Biology direct 2025 Jul 16;20(1):84
HIF-1α/BNIP3-Mediated Endoplasmic Reticulum Degradation via Autophagy Protects Against Ischemia Reperfusion-Induced Acute Kidney Injury.
Zhao H, Yang M, Han Y, Jiang N, Liu Y, Li C, Yang J, Luo S, Liu C, Sun L, Liu F, Liu Y
Antioxidants & redox signaling 2025 Feb;42(4-6):212-227
Antioxidants & redox signaling 2025 Feb;42(4-6):212-227
GSTK1 and RETREG1/FAM134B-mediated reticulophagy attenuates tubular injury in diabetic nephropathy through endoplasmic reticulum stress and apoptosis.
Zhang S, Chen W, Wang W, Liu Y, Zhao C, Yang K, Dai W, Ou Y, Yin X, Long Y, Liu Y, Zhang L, Sun L, Liu F, Xiao L
Autophagy 2025 Dec;21(12):2826-2841
Autophagy 2025 Dec;21(12):2826-2841
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity.
Jin S, Yan M, Liu Y, Zhang S, Song H, Cao C, Li Y, Sun G, Ye L, Chen J, Han W, Li L, Chang Q
Autophagy 2025 Dec;21(12):2614-2632
Autophagy 2025 Dec;21(12):2614-2632
Metformin Ameliorates Early Brain Injury After Subarachnoid Hemorrhage Via Improving Endoplasmic Reticulum Stress and Mitochondrial Stress-Mediated Ca(2+) Imbalance.
Zhang Z, Zhang J, Li L, Zong L
Molecular neurobiology 2025 Dec 5;63(1):256
Molecular neurobiology 2025 Dec 5;63(1):256
Cholesterol induced-mitochondrial calcium dysregulation facilitates atherosclerosis by promoting lipid accumulation in vascular smooth muscle cells.
Zhang Z, Yang F, Wang W, Cao Q, Zhang L, Zhang Y, Ma D, Zhang X, Wen J, Zheng B
Molecular biomedicine 2025 Dec 2;6(1):129
Molecular biomedicine 2025 Dec 2;6(1):129
RHOA regulates mitochondria-ER contact sites through modulation of the VAPB/PTPIP51 tether.
Yang Z, Nakajima S, Chen H, Chakrabarty Y, Feng H, Chan DC
Nature communications 2025 Dec 14;16(1):11260
Nature communications 2025 Dec 14;16(1):11260
Synergistic chemoimmunotherapy using pirarubicin-loaded tumor-derived extracellular vesicles for triple-negative breast cancer (TNBC).
Sun Q, Yu S, Shi R, Xu M, Ma P, Lv FY
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Dec 1;215:107331
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Dec 1;215:107331
Adhesive hydrogel based on Konjac Glucomannan (KGM) loaded with siACTC1-exosomes for enhanced post-surgical keloid treatment.
Zhong Y, Zhang Y, Liu Y, Zeng K, Fan L, Wang Q, Zhang J
International journal of biological macromolecules 2025 Aug;319(Pt 3):145360
International journal of biological macromolecules 2025 Aug;319(Pt 3):145360
Stereo-cell: Spatial enhanced-resolution single-cell sequencing with high-density DNA nanoball-patterned arrays.
Liao S, Zhou X, Liu C, Liu C, Hao S, Luo H, Hou H, Liu Q, Zhang Z, Xiao L, Xu Y, Huang Y, Zhou S, Li X, Wang Y, Xie L, Zhou Z, Dong S, Wang Y, Xu X, Guo P, Lin X, Lei J, Wang Q, Gong Y, Cheng J, Yuan Z, Yang Y, Huang Z, Li S, Zheng Y, Yang S, Huang X, Liu W, Li M, Deng Z, Yang X, Yin J, Luo Y, Lai Y, Yuan Y, Cheng M, Wang B, Ji J, Esteban MA, Li Y, Gu Y, Ruan Y, Chen L, Wang X, Xie J, Wang J, Liu L, Chen A, Xu X
Science (New York, N.Y.) 2025 Aug 21;389(6762):eadr0475
Science (New York, N.Y.) 2025 Aug 21;389(6762):eadr0475
Cdk5rap3-mediated regulation of lysosomal and ER membrane proteins is pivotal for the survival and function of pancreatic acinar cells.
Huang Y, Zhou F, Xu X, Wang Y, Quintero M, Liu S, Liu C, Zhu G, Cai Y, Dong Z, Bollag R, Wu G, Sabbatini ME, Li H
American journal of physiology. Cell physiology 2025 Aug 1;329(2):C513-C529
American journal of physiology. Cell physiology 2025 Aug 1;329(2):C513-C529
Lymph node-targeted delivery of Lonicera japonica thunb. polysaccharides for enhancing antitumor immunotherapy.
Zhang J, Liu J, Zhang H, Liu B, Li L, Li Y, Pei J, Lin Q, Chen Q, Lin J
Materials today. Bio 2025 Apr;31:101559
Materials today. Bio 2025 Apr;31:101559
TMED9 coordinates the clearance of misfolded GPI-anchored proteins out of the ER and into the Golgi.
Ronzier E, Satpute-Krishnan P
PLoS biology 2025 Apr;23(4):e3003084
PLoS biology 2025 Apr;23(4):e3003084
Cytochrome P450 2E1 aggravates DXR-induced myocardial injury through imbalanced mitochondrial OPA1.
Ma J, Wang Y, Lv H, Lei Y, Guan F, Dong W, Wang H, Zhang L, Lu D
Cell communication and signaling : CCS 2025 Apr 30;23(1):208
Cell communication and signaling : CCS 2025 Apr 30;23(1):208
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis.
Li N, Zhao L, Geng X, Liu J, Zhang X, Hu Y, Qi J, Chen H, Qiu J, Zhang X, Jin S
Theranostics 2024;14(11):4278-4296
Theranostics 2024;14(11):4278-4296
Physical exercise-induced circAnks1b upregulation promotes protective endoplasmic reticulum stress and suppresses apoptosis via miR-130b-5p/Pak2 signaling in an ischemic stroke model.
Yang X, Mu Y, Feng Y, Li M, Hu H, Zhang X, Zuo Z, Wu R, Xu J, Zheng F, He X, Hu X, Zhang L
CNS neuroscience & therapeutics 2024 Sep;30(9):e70055
CNS neuroscience & therapeutics 2024 Sep;30(9):e70055
The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress.
Ma Y, Guo J, Rao H, Xin J, Song X, Liu R, Shao S, Hou J, Kong L, Hu Z, He L, Pan F, Guo Z
Journal of extracellular vesicles 2024 Sep;13(9):e12505
Journal of extracellular vesicles 2024 Sep;13(9):e12505
Proteomic Profiling of Unannotated Microproteins in Human Placenta Reveals XRCC6P1 as a Potential Negative Regulator of Translation.
Li Q, Liu F, Ma X, Chen F, Yi Z, Du Y, Huang A, Zhao C, Wang D, Chen Y, Cao X
Journal of proteome research 2024 Sep 6;23(9):4005-4013
Journal of proteome research 2024 Sep 6;23(9):4005-4013
Development of a Signal-integrating Reporter to Monitor Mitochondria-ER Contacts.
Yang Z, Chan DC
ACS synthetic biology 2024 Sep 20;13(9):2791-2803
ACS synthetic biology 2024 Sep 20;13(9):2791-2803
Dihydroartemisinin inhibits ATP6 activity, reduces energy metabolism of hepatocellular carcinoma cells, promotes apoptosis and inhibits metastasis via CANX.
Chang J, Yang Q, Liu X, Li W, Gao L
Oncology letters 2024 Oct;28(4):474
Oncology letters 2024 Oct;28(4):474
Plasma-derived exosome miR-10a-5p promotes premature ovarian failure by target BDNF via the TrkB/Akt/mTOR signaling pathway.
Bao Z, Li J, Cai J, Yao S, Yang N, Yang J, Zhao B, Chen Y, Wu X
International journal of biological macromolecules 2024 Oct;277(Pt 1):134195
International journal of biological macromolecules 2024 Oct;277(Pt 1):134195
Selective regulation of aspartyl intramembrane protease activity by calnexin.
Contreras W, Groenendyk J, Gentzel M, Schönberg PY, Buchholz F, Michalak M, Schröder B, Mentrup T
Cellular and molecular life sciences : CMLS 2024 Oct 26;81(1):441
Cellular and molecular life sciences : CMLS 2024 Oct 26;81(1):441
Induction of tau pathology and motor dysfunction in mice by urinary exosomes from progressive supranuclear palsy patients.
Li Q, Liu H, Zhu Q, Zhang R, Liang D, Zhang J, Jin R, Chen Y, Qin C, Teng J
Brain research bulletin 2024 Oct 1;216:111046
Brain research bulletin 2024 Oct 1;216:111046
Circulating extracellular vesicles from severe COVID-19 patients induce lung inflammation.
Qian H, Zang R, Zhang R, Zheng G, Qiu G, Meng J, Wang J, Xia J, Huang R, Le Z, Shu Q, Xu J
mSphere 2024 Nov 21;9(11):e0076424
mSphere 2024 Nov 21;9(11):e0076424
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Huang Q, Chu Z, Wang Z, Li Q, Meng S, Lu Y, Ma K, Cui S, Hu W, Zhang W, Wei Q, Qu Y, Li H, Fu X, Zhang C
Nature communications 2024 May 9;15(1):3904
Nature communications 2024 May 9;15(1):3904
AGR2-mediated unconventional secretion of 14-3-3ε and α-actinin-4, responsive to ER stress and autophagy, drives chemotaxis in canine mammary tumor cells.
Yuan SH, Wu CC, Wang YC, Chan XY, Chu HW, Yang Y, Liu HP
Cellular & molecular biology letters 2024 May 31;29(1):84
Cellular & molecular biology letters 2024 May 31;29(1):84
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
Zhang Q, Li Y, Zhu Q, Xie T, Xiao Y, Zhang F, Li N, Deng K, Xin H, Huang X
Cell death & disease 2024 May 22;15(5):355
Cell death & disease 2024 May 22;15(5):355
Exosomes From IgE-Stimulated Mast Cells Aggravate Asthma-Mediated Atherosclerosis Through circRNA CDR1as-Mediated Endothelial Cell Dysfunction in Mice.
Yang H, Chen J, Liu S, Xue Y, Li Z, Wang T, Jiao L, An Q, Liu B, Wang J, Zhao H
Arteriosclerosis, thrombosis, and vascular biology 2024 Mar;44(3):e99-e115
Arteriosclerosis, thrombosis, and vascular biology 2024 Mar;44(3):e99-e115
The HRI branch of the integrated stress response selectively triggers mitophagy.
Chakrabarty Y, Yang Z, Chen H, Chan DC
Molecular cell 2024 Mar 21;84(6):1090-1100.e6
Molecular cell 2024 Mar 21;84(6):1090-1100.e6
NSP6 inhibits the production of ACE2-containing exosomes to promote SARS-CoV-2 infectivity.
Lv X, Chen R, Liang T, Peng H, Fang Q, Xiao S, Liu S, Hu M, Yu F, Cao L, Zhang Y, Pan T, Xi Z, Ding Y, Feng L, Zeng T, Huang W, Zhang H, Ma X
mBio 2024 Mar 13;15(3):e0335823
mBio 2024 Mar 13;15(3):e0335823
Chemoproteomics enables identification of coatomer subunit zeta-1 targeted by a small molecule for enterovirus A71 inhibition.
Li X, Zhang J, Xiao Y, Song H, Li Y, Li W, Cao R, Li S, Qin Y, Wang C, Zhong W
MedComm 2024 Jun;5(6):e587
MedComm 2024 Jun;5(6):e587
AS1411 binds to nucleolin via its parallel structure and disrupts the exos-miRNA-27a-mediated reciprocal activation loop between glioma and astrocytes.
Sun X, Zhang W, Gou C, Wang X, Wang X, Shao X, Chen X, Chen Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167211
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167211
Mitochondrial translation failure represses cholesterol gene expression via Pyk2-Gsk3β-Srebp2 axis.
Toshima T, Yagi M, Do Y, Hirai H, Kunisaki Y, Kang D, Uchiumi T
Life science alliance 2024 Jul;7(7)
Life science alliance 2024 Jul;7(7)
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Li J, Li X, Li X, Liang Z, Wang Z, Shahzad KA, Xu M, Tan F
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Liu YT, Zhang H, Duan SB, Wang JW, Chen H, Zhan M, Zhang W, Li AM, Liu Y, Yang Y, Yang S
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Targeting KDM4 family epigenetically triggers antitumour immunity via enhancing tumour-intrinsic innate sensing and immunogenicity.
Sun M, Han X, Li J, Zheng J, Li J, Wang H, Li X
Clinical and translational medicine 2024 Feb;14(2):e1598
Clinical and translational medicine 2024 Feb;14(2):e1598
Development of a signal-integrating reporter to monitor mitochondria-ER contacts.
Yang Z, Chan DC
bioRxiv : the preprint server for biology 2024 Feb 14;
bioRxiv : the preprint server for biology 2024 Feb 14;
Exosomes from adipose-derived stem cells overexpressing microRNA-671-3p promote fat graft angiogenesis and adipogenic differentiation.
Hao X, Guo Y, Yu X, He L, He Y, Shu M
Tissue & cell 2024 Dec;91:102575
Tissue & cell 2024 Dec;91:102575
Modulation of the unfolded protein response by white spot syndrome virus via wsv406 targeting BiP to facilitate viral replication.
Chen S, Zhong Q, Liao X, Wang H, Xiao B, He J, Li C
Virologica Sinica 2024 Dec;39(6):938-950
Virologica Sinica 2024 Dec;39(6):938-950
A roadmap for ribosome assembly in human mitochondria.
Lavdovskaia E, Hanitsch E, Linden A, Pašen M, Challa V, Horokhovskyi Y, Roetschke HP, Nadler F, Welp L, Steube E, Heinrichs M, Mai MM, Urlaub H, Liepe J, Richter-Dennerlein R
Nature structural & molecular biology 2024 Dec;31(12):1898-1908
Nature structural & molecular biology 2024 Dec;31(12):1898-1908
The SLE-associated TREX1-P212fs mutation disrupts ER association leading to type I interferonopathy.
Xu S, Xiao N, Du H, Zhou X, Huang M, Feng S, Hu S, Zhang X, Zhang S, Cui D, Zhang S, Chen Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70213
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70213
Carnosic Acid: A Novel Selective Inhibitor of ERAP1 by Direct Binding and Its Modulation of Antigen Processing and Presentation.
Wu J, Li Z, Liu X, Feng D, Liang R, Su X, Li D, Hua H, Cao H
Journal of agricultural and food chemistry 2024 Aug 7;72(31):17343-17355
Journal of agricultural and food chemistry 2024 Aug 7;72(31):17343-17355
Targeted treatment of rat AKI induced by rhabdomyolysis using BMSC derived magnetic exosomes and its mechanism.
Chen Y, Hou S
Nanoscale advances 2024 Aug 6;6(16):4180-4195
Nanoscale advances 2024 Aug 6;6(16):4180-4195
Two-Step Enrichment Facilitates Background Reduction for Proteomic Analysis of Lysosomes.
Bonini S, Winter D
Journal of proteome research 2024 Aug 2;23(8):3393-3403
Journal of proteome research 2024 Aug 2;23(8):3393-3403
Deletion of Emc1 in photoreceptor cells causes retinal degeneration in mice.
Li X, Jiang Z, Su Y, Wang K, Jiang X, Sun K, Yang Y, Zhou Y, Zhu X, Zhang L
The FEBS journal 2023 Sep;290(17):4356-4370
The FEBS journal 2023 Sep;290(17):4356-4370
DWL-4-140: A allene small molecule targeting STING that alleviates lupus-like phenotype in Trex1(-/-) mice.
Du H, Kou M, Deng W, Zhou X, Zhang X, Huang Z, Ren B, Cai X, Xu S, Chen Y, Chen L, Chen C, Bao H, Chen Q, Li D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115188
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115188
Dysregulation of MicroRNAs Derived from Plasma Extracellular Vesicles in Schizoaffective Disorder.
Chen R, Shi J, Yang H, Zhang M, Chen Q, He Q
Molecular neurobiology 2023 Nov;60(11):6373-6382
Molecular neurobiology 2023 Nov;60(11):6373-6382
Hsa_circ_0041150 serves as a novel biomarker for monitoring chemotherapy resistance in small cell lung cancer patients treated with a first-line chemotherapy regimen.
Zhang Y, Chao F, Lv L, Li M, Shen Z
Journal of cancer research and clinical oncology 2023 Nov;149(17):15365-15382
Journal of cancer research and clinical oncology 2023 Nov;149(17):15365-15382
ATAD1 inhibits hepatitis C virus infection by removing the viral TA-protein NS5B from mitochondria.
Zhou Q, Yang Y, Xu Z, Deng K, Zhang Z, Hao J, Li N, Wang Y, Wang Z, Chen H, Yang Y, Xiao F, Zhang X, Gao S, Li YP
EMBO reports 2023 Nov 6;24(11):e56614
EMBO reports 2023 Nov 6;24(11):e56614
Deficiency of RAB39B Activates ER Stress-Induced Pro-apoptotic Pathway and Causes Mitochondrial Dysfunction and Oxidative Stress in Dopaminergic Neurons by Impairing Autophagy and Upregulating α-Synuclein.
Chiu CC, Weng YH, Yeh TH, Lu JC, Chen WS, Li AH, Chen YL, Wei KC, Wang HL
Molecular neurobiology 2023 May;60(5):2706-2728
Molecular neurobiology 2023 May;60(5):2706-2728
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation.
Zhou GF, Tang J, Ma YL, Fu X, Liu JY, Yang RZ, Zhang HS, Cai XH, Wang JW, Xie XY, Song L, Luo B, Chen J, Chen L, Deng XJ, Chen GJ
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2220148120
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2220148120
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Xiao X, Shi J, He C, Bu X, Sun Y, Gao M, Xiang B, Xiong W, Dai P, Mao Q, Xing X, Yao Y, Yu H, Xu G, Li S, Ren Y, Chen B, Jiang C, Meng G, Lee YR, Wei W, Freeman GJ, Xie C, Zhang J
Nature communications 2023 May 19;14(1):2859
Nature communications 2023 May 19;14(1):2859
Targeting ATAD3A-PINK1-mitophagy axis overcomes chemoimmunotherapy resistance by redirecting PD-L1 to mitochondria.
Xie XQ, Yang Y, Wang Q, Liu HF, Fang XY, Li CL, Jiang YZ, Wang S, Zhao HY, Miao JY, Ding SS, Liu XD, Yao XH, Yang WT, Jiang J, Shao ZM, Jin G, Bian XW
Cell research 2023 Mar;33(3):215-228
Cell research 2023 Mar;33(3):215-228
Multi-Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins.
Akter F, Bonini S, Ponnaiyan S, Kögler-Mohrbacher B, Bleibaum F, Damme M, Renard BY, Winter D
Molecular & cellular proteomics : MCP 2023 Mar;22(3):100509
Molecular & cellular proteomics : MCP 2023 Mar;22(3):100509
Charcot-Marie-Tooth-1A and sciatic nerve crush rat models: insights from proteomics.
Msheik Z, Durand S, Pinault E, Caillaud M, Vignaud L, Billet F, El Massry M, Desmouliere A
Neural regeneration research 2023 Jun;18(6):1354-1363
Neural regeneration research 2023 Jun;18(6):1354-1363
Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1.
Li J, Zhao B, Yao S, Dai Y, Zhang X, Yang N, Bao Z, Cai J, Chen Y, Wu X
International journal of molecular sciences 2023 Feb 16;24(4)
International journal of molecular sciences 2023 Feb 16;24(4)
Extracellular vesicles encapsulated with caspase-1 inhibitor ameliorate experimental autoimmune myasthenia gravis through targeting macrophages.
Zhou Y, Du T, Yang CL, Li T, Li XL, Liu W, Zhang P, Dong J, Si WY, Duan RS, Wang CC
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:458-472
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:458-472
Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.
Li J, Zhao B, Dai Y, Zhang X, Chen Y, Wu X
Oxidative medicine and cellular longevity 2022;2022:9042345
Oxidative medicine and cellular longevity 2022;2022:9042345
Long Noncoding RNA SBF2-AS1 Promotes Abdominal Aortic Aneurysm Formation through the miRNA-520f-3p/SMARCD1 Axis.
Han B, Yang M, Liu Q, Wang G, Hou J
Disease markers 2022;2022:4782361
Disease markers 2022;2022:4782361
Safety and biodistribution of exosomes derived from human induced pluripotent stem cells.
Gu Z, Yin Z, Song P, Wu Y, He Y, Zhu M, Wu Z, Zhao S, Huang H, Wang H, Tong C, Qi Z
Frontiers in bioengineering and biotechnology 2022;10:949724
Frontiers in bioengineering and biotechnology 2022;10:949724
Substitution of SERCA2 Cys(674) aggravates cardiac fibrosis by promoting the transformation of cardiac fibroblasts to cardiac myofibroblasts.
Huang X, Lin X, Wang L, Xie Y, Que Y, Li S, Hu P, Tong X
Biochemical pharmacology 2022 Sep;203:115164
Biochemical pharmacology 2022 Sep;203:115164
A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis.
Stomberski CT, Venetos NM, Zhou HL, Qian Z, Collison BR, Field SJ, Premont RT, Stamler JS
Cell reports 2022 Oct 25;41(4):111538
Cell reports 2022 Oct 25;41(4):111538
Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo.
Singh J, Elhabashy H, Muthukottiappan P, Stepath M, Eisenacher M, Kohlbacher O, Gieselmann V, Winter D
Nature communications 2022 Oct 20;13(1):6212
Nature communications 2022 Oct 20;13(1):6212
Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis.
You M, Wu F, Gao M, Chen M, Zeng S, Zhang Y, Zhao W, Li D, Wei L, Ruan XZ, Chen Y
Redox biology 2022 Nov;57:102500
Redox biology 2022 Nov;57:102500
Porcine deltacoronavirus accessory protein NS7a possesses the functional characteristics of a viroporin.
Xia S, Fang P, Pan T, Xiao W, Zhang H, Zhu X, Xiao S, Fang L
Veterinary microbiology 2022 Nov;274:109551
Veterinary microbiology 2022 Nov;274:109551
Blood plasma derived extracellular vesicles (BEVs): particle purification liquid chromatography (PPLC) and proteomic analysis reveals BEVs as a potential minimally invasive tool for predicting response to breast cancer treatment.
Alvarez FA, Kaddour H, Lyu Y, Preece C, Cohen J, Baer L, Stopeck AT, Thompson P, Okeoma CM
Breast cancer research and treatment 2022 Nov;196(2):423-437
Breast cancer research and treatment 2022 Nov;196(2):423-437
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
Song P, Yang W, Lou KF, Dong H, Zhang H, Wang B, Chen D
EMBO reports 2022 Nov 7;23(11):e55099
EMBO reports 2022 Nov 7;23(11):e55099
Differential expression of exosomal microRNAs in fresh and senescent apheresis platelet concentrates.
Mi Z, Gong L, Kong Y, Zhao P, Yin Y, Xu H, Tian L, Liu Z
Platelets 2022 Nov 17;33(8):1260-1269
Platelets 2022 Nov 17;33(8):1260-1269
A new integrated method for tissue extracellular vesicle enrichment and proteome profiling.
Zhang M, Liu T, Du Z, Li H, Qin W
RSC advances 2022 Nov 15;12(51):33409-33418
RSC advances 2022 Nov 15;12(51):33409-33418
The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
Yu W, Xu G, Chen H, Xiao L, Liu G, Hu P, Li S, Kasim V, Zeng C, Tong X
Acta pharmaceutica Sinica. B 2022 May;12(5):2315-2329
Acta pharmaceutica Sinica. B 2022 May;12(5):2315-2329
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Li C, Li L, Yang M, Yang J, Zhao C, Han Y, Zhao H, Jiang N, Wei L, Xiao Y, Liu Y, Xiong X, Xi Y, Luo S, Deng F, Chen W, Yuan S, Zhu X, Xiao L, Sun L
Diabetes 2022 May 1;71(5):1034-1050
Diabetes 2022 May 1;71(5):1034-1050
Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6.
Qiu N, Abegg D, Guidi M, Gilmore K, Seeberger PH, Adibekian A
Cell chemical biology 2022 Mar 17;29(3):530-537.e7
Cell chemical biology 2022 Mar 17;29(3):530-537.e7
Cellular ESCRT components are recruited to regulate the endocytic trafficking and RNA replication compartment assembly during classical swine fever virus infection.
Liu CC, Liu YY, Zhou JF, Chen X, Chen H, Hu JH, Chen J, Zhang J, Sun RC, Wei JC, Go YY, Morita E, Zhou B
PLoS pathogens 2022 Feb;18(2):e1010294
PLoS pathogens 2022 Feb;18(2):e1010294
Construction and analysis of expression profile of exosomal lncRNAs in pleural effusion in lung adenocarcinoma.
Huang X, Zhou H, Yang X, Shi W, Hu L, Wang J, Zhang F, Shao F, Zhang M, Jiang F, Wang Y
Journal of clinical laboratory analysis 2022 Dec;36(12):e24777
Journal of clinical laboratory analysis 2022 Dec;36(12):e24777
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Wu X, Zhang H, Jiang G, Peng M, Li C, Lu J, Jiang S, Yang X, Jiang Y
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
Xu Z, Xu J, Sun S, Lin W, Li Y, Lu Q, Li F, Yang Z, Lu Y, Liu W
Redox biology 2022 Aug;54:102351
Redox biology 2022 Aug;54:102351
Osteosarcoma Cell-Derived Small Extracellular Vesicles Enhance Osteoclastogenesis and Bone Resorption Through Transferring MicroRNA-19a-3p.
Luo T, Zhou X, Jiang E, Wang L, Ji Y, Shang Z
Frontiers in oncology 2021;11:618662
Frontiers in oncology 2021;11:618662
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Sun NN, Zhang Y, Huang WH, Zheng BJ, Jin SY, Li X, Meng Y
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
Ge L, Xun C, Li W, Jin S, Liu Z, Zhuo Y, Duan D, Hu Z, Chen P, Lu M
Journal of nanobiotechnology 2021 Nov 21;19(1):380
Journal of nanobiotechnology 2021 Nov 21;19(1):380
IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells.
Peng X, Yang L, Ma Y, Li X, Yang S, Li Y, Wu B, Tang S, Zhang F, Zhang B, Liu J, Li H
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118857
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118857
Exosome-Delivered LncHEIH Promotes Gastric Cancer Progression by Upregulating EZH2 and Stimulating Methylation of the GSDME Promoter.
Lu Y, Hou K, Li M, Wu X, Yuan S
Frontiers in cell and developmental biology 2020;8:571297
Frontiers in cell and developmental biology 2020;8:571297
ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy.
Lin Q, Zhou S, Huang Y, Huo Z, Chen C, Luo X, He J, Liu C, Zhang P
Frontiers in microbiology 2020;11:1745
Frontiers in microbiology 2020;11:1745
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