Tissue expression
Cell line expression

TNFSF9

gene product
4-1BB-L, 4-1BBL 
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. [provided by RefSeq, Oct 2008]
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668 antibodies from 40 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
91 antibodies
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31 antibodies
antibodies-online
147 antibodies
NSJ Bioreagents
1 antibody
GeneTex
10 antibodies
Cusabio Biotech Co., Ltd
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Affinity Biosciences
1 antibody
LifeSpan BioSciences, Inc.
86 antibodies
Invitrogen Antibodies
16 antibodies
OriGene
13 antibodies
Biorbyt
24 antibodies
Boster Biological Technology
2 antibodies
Bioworld Technology, Inc
1 antibody
PeproTech Inc.
9 antibodies
Aviva Systems Biology
4 antibodies
RabMAbs
2 antibodies
NovoPro Bioscience Inc.
7 antibodies
Cell Signaling Technology, Inc
2 antibodies
Proteintech Group
1 antibody
Acris Antibodies GmbH
8 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
BioLegend
14 antibodies
Abnova Corporation
4 antibodies
Sino Biological Inc.
6 antibodies
Creative Diagnostics
7 antibodies
Atlas Antibodies
1 antibody
Miltenyi Biotec
33 antibodies
Absolute Antibody
11 antibodies
Abbexa
9 antibodies
Creative Biolabs
67 antibodies
St John's Laboratory
2 antibodies
MyBioSource
9 antibodies
ProSci
4 antibodies
Abgent
2 antibodies
Bethyl Laboratories
1 antibody
United States Biological
14 antibodies
RayBiotech, Inc.
2 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
EMD Millipore
1 antibody