BS6555

antibody from Bioworld Technology, Inc
Targeting: CD70 CD27L, CD27LG, TNFSF7
Provider product page for BS6555
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6555 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CD70 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CD70.
Description
The tumor necrosis factor (TNF) receptor family is composed of several type I integral membrane glycoproteins that exhibit homology in their cystine-rich extracellular domains. Members of this family include FAS, OX40, CD27 and CD30. Ligands for these receptors are often type II transmembrane glycoproteins, as is the case for CD27 and CD30. CD27 is a homodimeric lymphocyte-specific surface antigen present on T and B lymphocytes. Activation of the CD3 complex via the T cell receptor for antigen leads to an increase in CD27 expression. Together, CD27 and its ligand, CD70, generate co-stimulatory signals required for complete T cell activation. CD30 is a surface marker for neoplastic cells of the Hodgkin£ªs lymphoma and related hematologic malignancies. CD30L has been shown to enhance the proliferation of the Hodgkin£ªs cell line HDLM-2, but exerts antiproliferative effects on large cell anaplastic lymphoma cell lines.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CD70 protein structure - BS6555 shown in red.