Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM01629G - Provider product page
- Provider
- Leading Biology
- Product name
- CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody - Without BSA and Azide
- Antibody type
- Monoclonal
- Description
- It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toĀinhibit T cell proliferation induced by dendritic cells.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- BU69
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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