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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 355101 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#355101, RRID:AB_2561428
- Product name
- Purified anti-human CD70
- Antibody type
- Monoclonal
- Antigen
- CD70-transfected L cells
- Description
- CD70, also known as CD27L, is a 50 kD type II transmembrane glycoprotein and member of the tumor necrosis factor superfamily. CD70 is expressed on activated T, B and NK cells, activated plasmacytoid dendritic cells (pDCs), and chronic B cell lymphocytic leukemia and large B cell lymphomas. CD70 costimulates T cell proliferation and differentiation. It plays a role in the pDC-induced B cell differentiation. The ligand of CD70 is CD27.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human myeloma cell line, U266, was stained with purified CD70 (clone 113-16, filled histogram) or mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG PE.
- Conjugate
- Unconjugated
