66414-1-Ig

antibody from Proteintech Group

Targeting: LDLR LDLCQ2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66414-1-Ig

Provider

Proteintech Group

Product name

LDLR antibody

Antibody type

Monoclonal

Description

LDLR antibody (Cat. #66414-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1A2A3

Vial size

20ul, 150ul

References

Submitted references

Characterization of the Probiotic Properties and Cholesterol Metabolism Regulation Potential of Lactiplantibacillus plantarum QL-19.

Liu M, Han Y, Wang S, Wang Y, Xu H
Probiotics and antimicrobial proteins 2026 Apr;18(3):3975-3990

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Transcriptomic-proteomic integration reveals RNGTT as a critical host factor mediating the replication of virulent but not attenuated SADS-CoV.

Chen Z, Huang Y, Li M, Peng O, Luo J, Pan Y, Kuang Z, Xu Z, Cao Y, Wei X, Xue C
Veterinary microbiology 2026 Apr 24;318:111045

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Targeting ApoE-KCC2 Signaling Rescues GABAergic Synaptic Dysfunction and Depression-like Behaviors in Mice.

Xu C, Liu J, Guo M, Wang J, Bai X, Zhang C, Luan X, Pei H, Liu H, Lv X, Ye X, Tang B, Chen M
Research (Washington, D.C.) 2025;8:0746

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Timosaponin A3 Ameliorates Prostate Cancer Progression via Upregulating STARD4 Mediated Cholesterol Metabolism.

Zhi Y, Ge L, Wang S, Zang W, Zhang Z, Xu T, Zhang Y, Song F, Huang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71063

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Reynoutrin targets EphB4 to ameliorate hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus.

Lyu D, Xiao H, Shao Z, Li S, Li M, Pan L, Li Z, Huang H
Biochemical pharmacology 2025 Nov;241:117132

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Low-density Lipoprotein Receptor is an important host factor in flaviviral entry and replication in neurons.

Bhaskar M, Satheesan A, Basu A
Biochemical and biophysical research communications 2025 Jan;743:151160

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Angiopoietin-like 8 governs osteoblast-adipocyte lineage commitment during skeletal aging.

Guo Y, Zhang Z, He J, Luo P, Wang Z, Zhu Y, Meng X, Pan L, Kan R, Xiang Y, Mao B, He Y, Wang S, Yang Y, Guo F, You H, Li F, Li D, Chen Y, Yu X
JCI insight 2025 Dec 8;10(23)

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Oncolytic Activity of Sindbis Virus with the Help of GM-CSF in Hepatocellular Carcinoma.

Shi X, Sun K, Li L, Xian J, Wang P, Jia F, Xu F
International journal of molecular sciences 2024 Jun 29;25(13)

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Nanoparticles for inducing Gaucher disease-like damage in cancer cells.

Yue C, Lu W, Fan S, Huang Z, Yang J, Dong H, Zhang X, Shang Y, Lai W, Li D, Dong T, Yuan A, Wu J, Kang L, Hu Y
Nature nanotechnology 2024 Aug;19(8):1203-1215

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Large-Scale CRISPR Screen of LDLR Pathogenic Variants.

Li M, Ma L, Chen Y, Li J, Wang Y, You W, Yuan H, Tang X, Ouyang H, Pang D
Research (Washington, D.C.) 2023;6:0203

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Limb-girdle muscular dystrophy type 2B causes HDL-C abnormalities in patients and statin-resistant muscle wasting in dysferlin-deficient mice.

White Z, Sun Z, Sauge E, Cox D, Donen G, Pechkovsky D, Straub V, Francis GA, Bernatchez P
Skeletal muscle 2022 Nov 29;12(1):25

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AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models.

Sun SM, Xie ZF, Zhang YM, Zhang XW, Zhou CD, Yin JP, Yu YY, Cui SC, Jiang HW, Li TT, Li J, Nan FJ, Li JY
Acta pharmacologica Sinica 2021 Apr;42(4):585-592

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Hydrogen sulfide inhibits PCSK9 expression through the PI3K/Akt‑SREBP‑2 signaling pathway to influence lipid metabolism in HepG2 cells.

Xiao J, Bai XQ, Liao L, Zhou M, Peng J, Xiang Q, Ren Z, Wen HY, Jiang ZS, Tang ZH, Wang MM, Liu LS
International journal of molecular medicine 2019 May;43(5):2055-2063