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- References [15]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 60309-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- pan Ras antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated pan Ras antibody (Cat. #60309-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4H4G7
- Vial size
- 20ul, 150ul
Submitted references Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.
Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin.
Jia-Wei-Si-Miao-Yong-An Fang stimulates the healing of acute radiation-induced cutaneous wounds through MAPK/ERK pathway.
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Upregulation of KLHL17 promotes the proliferation and migration of non-small cell lung cancer by activating the Ras/MAPK signaling pathway.
TCR activation directly stimulates PYGB-dependent glycogenolysis to fuel the early recall response in CD8(+) memory T cells.
Autophagy Contributes to Oxidative Stress-Induced Apoptosis in Porcine Granulosa Cells.
DEPDC1 up-regulates RAS expression to inhibit autophagy in lung adenocarcinoma cells.
Destabilization of β-catenin and RAS by targeting the Wnt/β-catenin pathway as a potential treatment for triple-negative breast cancer.
The immunoreactivity of the anti-p21Ras single-chain fragment variant KGH-R1 and its predicted binding sites to p21Ras.
Modulation of YrdC promotes hepatocellular carcinoma progression via MEK/ERK signaling pathway.
EGF upregulates RFPL3 and hTERT via the MEK signaling pathway in non‑small cell lung cancer cells.
KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis.
Overexpression of wild-type p21Ras plays a prominent role in colorectal cancer.
FOXP1 forkhead transcription factor is associated with the pathogenesis of endometrial cancer.
Yang W, Wei Y, Wang T, Xu Y, Jin X, Qian H, Yang S, He S
International journal of molecular medicine 2024 Apr;53(4)
International journal of molecular medicine 2024 Apr;53(4)
Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin.
Guo Y, Tian J, Guo Y, Wang C, Chen C, Cai S, Yu W, Sun B, Yan J, Li Z, Fan J, Qi Q, Zhang D, Jin W, Hua Z, Chen G
Cell reports 2023 Dec 26;42(12):113511
Cell reports 2023 Dec 26;42(12):113511
Jia-Wei-Si-Miao-Yong-An Fang stimulates the healing of acute radiation-induced cutaneous wounds through MAPK/ERK pathway.
Wang Y, Gao J, Sun L, Li Q, Kang N, Gao C, Li T
Journal of ethnopharmacology 2023 Apr 24;306:116180
Journal of ethnopharmacology 2023 Apr 24;306:116180
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Yang X, Shang P, Ji J, Malichewe C, Yao Z, Liao J, Du D, Sun C, Wang L, Tang YJ, Guo X
Molecular pharmaceutics 2022 Jan 3;19(1):2-17
Molecular pharmaceutics 2022 Jan 3;19(1):2-17
Upregulation of KLHL17 promotes the proliferation and migration of non-small cell lung cancer by activating the Ras/MAPK signaling pathway.
Liu Z, Zhao M, Jiang X, Zhang Y, Zhang S, Xu Y, Ren H, Su H, Wang H, Qiu X
Laboratory investigation; a journal of technical methods and pathology 2022 Dec;102(12):1389-1399
Laboratory investigation; a journal of technical methods and pathology 2022 Dec;102(12):1389-1399
TCR activation directly stimulates PYGB-dependent glycogenolysis to fuel the early recall response in CD8(+) memory T cells.
Zhang H, Liu J, Yang Z, Zeng L, Wei K, Zhu L, Tang L, Wang D, Zhou Y, Lv J, Zhou N, Tang K, Ma J, Huang B
Molecular cell 2022 Aug 18;82(16):3077-3088.e6
Molecular cell 2022 Aug 18;82(16):3077-3088.e6
Autophagy Contributes to Oxidative Stress-Induced Apoptosis in Porcine Granulosa Cells.
Zhang JQ, Ren QL, Chen JF, Gao BW, Wang XW, Zhang ZJ, Wang J, Xu ZJ, Xing BS
Reproductive sciences (Thousand Oaks, Calif.) 2021 Aug;28(8):2147-2160
Reproductive sciences (Thousand Oaks, Calif.) 2021 Aug;28(8):2147-2160
DEPDC1 up-regulates RAS expression to inhibit autophagy in lung adenocarcinoma cells.
Wang W, Li A, Han X, Wang Q, Guo J, Wu Y, Wang C, Huang G
Journal of cellular and molecular medicine 2020 Nov;24(22):13303-13313
Journal of cellular and molecular medicine 2020 Nov;24(22):13303-13313
Destabilization of β-catenin and RAS by targeting the Wnt/β-catenin pathway as a potential treatment for triple-negative breast cancer.
Ryu WJ, Lee JD, Park JC, Cha PH, Cho YH, Kim JY, Sohn JH, Paik S, Choi KY
Experimental & molecular medicine 2020 May;52(5):832-842
Experimental & molecular medicine 2020 May;52(5):832-842
The immunoreactivity of the anti-p21Ras single-chain fragment variant KGH-R1 and its predicted binding sites to p21Ras.
Wang P, Pan X, Feng Q, Zou H, Cui J, He Y, Luo Y, Yang J
Immunotherapy 2020 Aug;12(12):879-890
Immunotherapy 2020 Aug;12(12):879-890
Modulation of YrdC promotes hepatocellular carcinoma progression via MEK/ERK signaling pathway.
Huang S, Zhu P, Sun B, Guo J, Zhou H, Shu Y, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108859
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108859
EGF upregulates RFPL3 and hTERT via the MEK signaling pathway in non‑small cell lung cancer cells.
Lin C, Qin Y, Zhang H, Gao MY, Wang YF
Oncology reports 2018 Jul;40(1):29-38
Oncology reports 2018 Jul;40(1):29-38
KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis.
Yuan P, He XH, Rong YF, Cao J, Li Y, Hu YP, Liu Y, Li D, Lou W, Liu MF
Cancer research 2017 Jan 1;77(1):100-111
Cancer research 2017 Jan 1;77(1):100-111
Overexpression of wild-type p21Ras plays a prominent role in colorectal cancer.
Bai S, Feng Q, Pan XY, Zou H, Chen HB, Wang P, Zhou XL, Hong YL, Song SL, Yang JL
International journal of molecular medicine 2017 Apr;39(4):861-868
International journal of molecular medicine 2017 Apr;39(4):861-868
FOXP1 forkhead transcription factor is associated with the pathogenesis of endometrial cancer.
Mizunuma M, Yokoyama Y, Futagami M, Horie K, Watanabe J, Mizunuma H
Heliyon 2016 May;2(5):e00116
Heliyon 2016 May;2(5):e00116
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 60309-1-Ig( KRAS Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KRAS antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human KRAS. This antibody recognizes human antigen. The KRAS antibody has been validated for the following applications: ELISA, WB, IHC analysis.
