Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 12522-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12522-1-AP, RRID:AB_2302772
- Product name
- SULT1E1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SULT1E1 antibody (Cat. #12522-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Developing liver-targeted naringenin nanoparticles for breast cancer endocrine therapy by promoting estrogen metabolism.
Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway.
RORα phosphorylation by casein kinase 1α as glucose signal to regulate estrogen sulfation in human liver cells.
PXR phosphorylated at Ser350 transduces a glucose signal to repress the estrogen sulfotransferase gene in human liver cells and fasting signal in mouse livers.
Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver.
Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice.
Hepatic Estrogen Sulfotransferase Distantly Sensitizes Mice to Hemorrhagic Shock-Induced Acute Lung Injury.
Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline.
Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature.
Sex- and Tissue-Specific Role of Estrogen Sulfotransferase in Energy Homeostasis and Insulin Sensitivity.
Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer.
Resveratrol and its methoxy derivatives modulate the expression of estrogen metabolism enzymes in breast epithelial cells by AhR down-regulation.
Farnesoid X receptor regulates SULT1E1 expression through inhibition of PGC1α binding to HNF4α.
Estrogen Sulfotransferase Is an Oxidative Stress-responsive Gene That Gender-specifically Affects Liver Ischemia/Reperfusion Injury.
Oestrogen sulfotransferase ablation sensitizes mice to sepsis.
Effects of PPAR-α agonist and IGF-1 on estrogen sulfotransferase in human vascular endothelial and smooth muscle cells.
Estrogen sulfotransferase (SULT1E1) regulates inflammatory response and lipid metabolism of human endothelial cells via PPARγ.
Effect of estrogen sulfation by SULT1E1 and PAPSS on the development of estrogen-dependent cancers.
Zhao Y, Tan H, Zhang J, Zhan D, Yang B, Hong S, Pan B, Wang N, Chen T, Shi Y, Wang Z
Journal of nanobiotechnology 2024 Mar 19;22(1):122
Journal of nanobiotechnology 2024 Mar 19;22(1):122
Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway.
Zhang J, Wang N, Zheng Y, Yang B, Wang S, Wang X, Pan B, Wang Z
Journal of advanced research 2023 May;47:189-207
Journal of advanced research 2023 May;47:189-207
RORα phosphorylation by casein kinase 1α as glucose signal to regulate estrogen sulfation in human liver cells.
Hu H, Negishi M
The Biochemical journal 2020 Sep 30;477(18):3583-3598
The Biochemical journal 2020 Sep 30;477(18):3583-3598
PXR phosphorylated at Ser350 transduces a glucose signal to repress the estrogen sulfotransferase gene in human liver cells and fasting signal in mouse livers.
Hu H, Yokobori K, Negishi M
Biochemical pharmacology 2020 Oct;180:114197
Biochemical pharmacology 2020 Oct;180:114197
Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver.
Yi M, Fashe M, Arakawa S, Moore R, Sueyoshi T, Negishi M
Scientific reports 2020 Mar 19;10(1):5001
Scientific reports 2020 Mar 19;10(1):5001
Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice.
Silva Barbosa AC, Zhou D, Xie Y, Choi YJ, Tung HC, Chen X, Xu M, Gibbs RB, Poloyac SM, Liu S, Yu Y, Luo J, Liu Y, Xie W
Journal of the American Society of Nephrology : JASN 2020 Jul;31(7):1496-1508
Journal of the American Society of Nephrology : JASN 2020 Jul;31(7):1496-1508
Hepatic Estrogen Sulfotransferase Distantly Sensitizes Mice to Hemorrhagic Shock-Induced Acute Lung Injury.
Xie Y, Barbosa ACS, Xu M, Oberly PJ, Ren S, Gibbs RB, Poloyac SM, Song WC, Fan J, Xie W
Endocrinology 2020 Jan 1;161(1)
Endocrinology 2020 Jan 1;161(1)
Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline.
Sun Z, Liu Y, Yu F, Xu Y, Yanli L, Liu N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108933
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108933
Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature.
Hashiguchi T, Shindo S, Chen SH, Hong JS, Negishi M
Drug metabolism and disposition: the biological fate of chemicals 2018 Jun;46(6):860-864
Drug metabolism and disposition: the biological fate of chemicals 2018 Jun;46(6):860-864
Sex- and Tissue-Specific Role of Estrogen Sulfotransferase in Energy Homeostasis and Insulin Sensitivity.
Garbacz WG, Jiang M, Xu M, Yamauchi J, Dong HH, Xie W
Endocrinology 2017 Nov 1;158(11):4093-4104
Endocrinology 2017 Nov 1;158(11):4093-4104
Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer.
Mungenast F, Aust S, Vergote I, Vanderstichele A, Sehouli J, Braicu E, Mahner S, Castillo-Tong DC, Zeillinger R, Thalhammer T
Oncology letters 2017 Jun;13(6):4047-4054
Oncology letters 2017 Jun;13(6):4047-4054
Resveratrol and its methoxy derivatives modulate the expression of estrogen metabolism enzymes in breast epithelial cells by AhR down-regulation.
Licznerska B, Szaefer H, Wierzchowski M, Sobierajska H, Baer-Dubowska W
Molecular and cellular biochemistry 2017 Jan;425(1-2):169-179
Molecular and cellular biochemistry 2017 Jan;425(1-2):169-179
Farnesoid X receptor regulates SULT1E1 expression through inhibition of PGC1α binding to HNF4α.
Wang S, Yuan X, Lu D, Guo L, Wu B
Biochemical pharmacology 2017 Dec 1;145:202-209
Biochemical pharmacology 2017 Dec 1;145:202-209
Estrogen Sulfotransferase Is an Oxidative Stress-responsive Gene That Gender-specifically Affects Liver Ischemia/Reperfusion Injury.
Guo Y, Hu B, Huang H, Tsung A, Gaikwad NW, Xu M, Jiang M, Ren S, Fan J, Billiar TR, Huang M, Xie W
The Journal of biological chemistry 2015 Jun 5;290(23):14754-64
The Journal of biological chemistry 2015 Jun 5;290(23):14754-64
Oestrogen sulfotransferase ablation sensitizes mice to sepsis.
Chai X, Guo Y, Jiang M, Hu B, Li Z, Fan J, Deng M, Billiar TR, Kucera HR, Gaikwad NW, Xu M, Lu P, Yan J, Fu H, Liu Y, Yu L, Huang M, Zeng S, Xie W
Nature communications 2015 Aug 10;6:7979
Nature communications 2015 Aug 10;6:7979
Effects of PPAR-α agonist and IGF-1 on estrogen sulfotransferase in human vascular endothelial and smooth muscle cells.
Li Y, Xu Y, Li X, Qin Y, Hu R
Molecular medicine reports 2013 Jul;8(1):133-9
Molecular medicine reports 2013 Jul;8(1):133-9
Estrogen sulfotransferase (SULT1E1) regulates inflammatory response and lipid metabolism of human endothelial cells via PPARγ.
Xu Y, Yang X, Wang Z, Li M, Ning Y, Chen S, Yin L, Li X
Molecular and cellular endocrinology 2013 Apr 30;369(1-2):140-9
Molecular and cellular endocrinology 2013 Apr 30;369(1-2):140-9
Effect of estrogen sulfation by SULT1E1 and PAPSS on the development of estrogen-dependent cancers.
Xu Y, Liu X, Guo F, Ning Y, Zhi X, Wang X, Chen S, Yin L, Li X
Cancer science 2012 Jun;103(6):1000-9
Cancer science 2012 Jun;103(6):1000-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SULT1E1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SULT1E1. This antibody recognizes human,mouse,rat antigen. The SULT1E1 antibody has been validated for the following applications: ELISA, WB analysis.