27171-1-AP

antibody from Proteintech Group

Targeting: NECTIN2 CD112, HVEB, PRR2, PVRL2, PVRR2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

27171-1-AP

Provider

Proteintech Group

Product name

Nectin-2/PVRL2 antibody

Antibody type

Polyclonal

Description

Nectin-2/PVRL2 antibody (Cat. #27171-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

ST6GalNAc-I regulates tumor cell sialylation via NECTIN2/MUC5AC-mediated immunosuppression and angiogenesis in non-small cell lung cancer.

Appadurai MI, Chaudhary S, Shah A, Natarajan G, Alsafwani ZW, Khan P, Shinde DD, Lele SM, Smith LM, Nasser MW, Batra SK, Ganti AK, Lakshmanan I
The Journal of clinical investigation 2025 May 15;135(10)

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Mitochondrial ROS-associated integrated stress response is involved in arsenic-induced blood-testis barrier disruption and protective effect of melatonin.

Niu FW, Liu MD, Yao K, Yang R, Gao L, Zhai JX, Wang C, Zhang SH, Xu DX, Zhang ZH
Environment international 2025 Mar;197:109346

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Dorsal CA1 NECTIN3 Reduction Mediates Early-Life Stress-Induced Object Recognition Memory Deficits in Adolescent Female Mice.

Ma YN, Zhang CC, Sun YX, Liu X, Li XX, Wang H, Wang T, Wang XD, Su YA, Li JT, Si TM
Neuroscience bulletin 2025 Feb;41(2):243-260

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Ara-C suppresses H3 K27-altered spinal cord diffuse midline glioma growth and enhances immune checkpoint blockade sensitivity.

Pang B, Wu Y, An S, Chang Y, Yan H, Lin H, Zhao Z, Wu F, Chang Q, Jia W, Jiang T, Wang Y, Chai R
Science advances 2025 Apr 18;11(16):eadu3956

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Single-cell RNA sequencing unveils tumor heterogeneity and immune microenvironment between subungual and plantar melanoma.

Wang P, Ma Y, Zhao Y, Li Y, Tang C, Wang S, Jin S, Wang J, Zhu M, Xie B, Wang P
Scientific reports 2024 Mar 25;14(1):7039

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Histone lactylation dynamics: Unlocking the triad of metabolism, epigenetics, and immune regulation in metastatic cascade of pancreatic cancer.

Wang X, Liu X, Xiao R, Fang Y, Zhou F, Gu M, Luo X, Jiang D, Tang Y, You L, Zhao Y
Cancer letters 2024 Aug 28;598:217117

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Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma.

Shen Y, Xu S, Ye C, Li Q, Chen R, Wu W, Jiang Q, Jia Y, Zhang X, Fan L, Fu W, Jiang M, Chen J, Timko MP, Zhao P, Ruan J
iScience 2023 Feb 17;26(2):106003

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Lipid-related protein NECTIN2 is an important marker in the progression of carotid atherosclerosis: An intersection of clinical and basic studies.

Li S, Gao Y, Ma K, Li Y, Liu C, Yan Y, Liu W, Liu H, Li Z, Song B, Xu Y, Xia Z
Journal of translational internal medicine 2021 Dec 1;9(4):294-306

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Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.

Wang C, Li Q, Lv J, Sun X, Cao Y, Yu K, Miao C, Zhang ZS, Yao Z, Wang Q
Mucosal immunology 2020 Jan;13(1):22-33