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- Antibody Data
- Antigen structure
- References [20]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA009128 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA009128, RRID:AB_1078613
- Product name
- Anti-CYP2E1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human CYP2E1, Gene description: cytochrome P450, family 2, subfamily E, polypeptide 1, Alternative Gene Names: CYP2E, Validated applications: WB, IHC, Uniprot ID: P05181, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Defining spatiotemporal gene modules in liver regeneration using Analytical Dynamic Visual Spatial Omics Representation (ADViSOR)
Inhibition of Abelson Tyrosine-Protein Kinase 2 Suppresses the Development of Alcohol-Associated Liver Disease by Decreasing PPARgamma Expression
Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury.
Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b
Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism
Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice
Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation
Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury
Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice
Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques.
Transcriptome analysis revealed key prognostic genes and microRNAs in hepatocellular carcinoma
Functional characterization of the chlorzoxazone 6-hydroxylation activity of human cytochrome P450 2E1 allelic variants in Han Chinese
The regulatory role of PGC1α‐related coactivator in response to drug‐induced liver injury
Liver lymphatic drainage patterns follow segmental anatomy in a murine model.
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Dietary Iron Overload Abrogates Chemically-Induced Liver Cirrhosis in Rats
Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer.
The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size
Alcohol Facilitates HCV RNA Replication Via Up‐Regulation of miR‐122 Expression and Inhibition of Cyclin G1 in Human Hepatoma Cells
Singh-Varma A, Shah A, Liu S, Zamora R, Monga S, Vodovotz Y
Hepatology Communications 2023;7(11)
Hepatology Communications 2023;7(11)
Inhibition of Abelson Tyrosine-Protein Kinase 2 Suppresses the Development of Alcohol-Associated Liver Disease by Decreasing PPARgamma Expression
Malnassy G, Keating C, Gad S, Bridgeman B, Perera A, Hou W, Cotler S, Ding X, Choudhry M, Sun Z, Koleske A, Qiu W
Cellular and Molecular Gastroenterology and Hepatology 2023;16(5):685-709
Cellular and Molecular Gastroenterology and Hepatology 2023;16(5):685-709
Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury.
Van Campenhout R, De Groof TWM, Kadam P, Kwak BR, Muyldermans S, Devoogdt N, Vinken M
Journal of nanobiotechnology 2023 Oct 11;21(1):371
Journal of nanobiotechnology 2023 Oct 11;21(1):371
Bragg R, Coffey S, Cantle J, Hu S, Singh S, Legg S, McHugh C, Toor A, Zeitlin S, Kwak S, Howland D, Vogt T, Monga S, Carroll J
2023
2023
Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b
Hu S, Liu S, Bian Y, Poddar M, Singh S, Cao C, McGaughey J, Bell A, Blazer L, Adams J, Sidhu S, Angers S, Monga S
Cell Reports Medicine 2022;3(10):100754
Cell Reports Medicine 2022;3(10):100754
Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism
Albadry M, Höpfl S, Ehteshamzad N, König M, Böttcher M, Neumann J, Lupp A, Dirsch O, Radde N, Christ B, Christ M, Schwen L, Laue H, Klopfleisch R, Dahmen U
Scientific Reports 2022;12(1)
Scientific Reports 2022;12(1)
Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice
Naim S, Fernandez-Marrero Y, de Brot S, Bachmann D, Kaufmann T
International Journal of Molecular Sciences 2021;22(6):3281
International Journal of Molecular Sciences 2021;22(6):3281
Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation
Koch P, Sandorski K, Heil J, Schmid C, Kürschner S, Hoffmann J, Winkler M, Staniczek T, de la Torre C, Sticht C, Schledzewski K, Taketo M, Trogisch F, Heineke J, Géraud C, Goerdt S, Olsavszky V
Frontiers in Physiology 2021;12
Frontiers in Physiology 2021;12
Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury
Schneider K, Elfers C, Ghallab A, Schneider C, Galvez E, Mohs A, Gui W, Candels L, Wirtz T, Zuehlke S, Spiteller M, Myllys M, Roulet A, Ouzerdine A, Lelouvier B, Kilic K, Liao L, Nier A, Latz E, Bergheim I, Thaiss C, Hengstler J, Strowig T, Trautwein C
Cellular and Molecular Gastroenterology and Hepatology 2021;11(4):909-933
Cellular and Molecular Gastroenterology and Hepatology 2021;11(4):909-933
Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice
Schuran F, Lommetz C, Steudter A, Ghallab A, Wieschendorf B, Schwinge D, Zuehlke S, Reinders J, Heeren J, Lohse A, Schramm C, Herkel J, Carambia A
Cellular and Molecular Gastroenterology and Hepatology 2021;11(2):371-388
Cellular and Molecular Gastroenterology and Hepatology 2021;11(2):371-388
Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques.
Matsuoka Y, Takahashi M, Sugiura Y, Izumi Y, Nishiyama K, Nishida M, Suematsu M, Bamba T, Yamada KI
Nature communications 2021 Nov 3;12(1):6339
Nature communications 2021 Nov 3;12(1):6339
Transcriptome analysis revealed key prognostic genes and microRNAs in hepatocellular carcinoma
Ma X, Zhou L, Zheng S
PeerJ 2020;8
PeerJ 2020;8
Functional characterization of the chlorzoxazone 6-hydroxylation activity of human cytochrome P450 2E1 allelic variants in Han Chinese
Wang T, Du H, Ma J, Shen L, Wei M, Zhao X, Chen L, Li M, Li G, Xing Q, He L, Qin S
PeerJ 2020;8
PeerJ 2020;8
The regulatory role of PGC1α‐related coactivator in response to drug‐induced liver injury
Buler M, Naessens T, Mattsson J, Morias Y, Söderberg M, Robbins P, Kärrberg L, Svensson T, Thulin P, Glinghammar B, Scarpulla R, Andersson U
FASEB BioAdvances 2020;2(8):453-463
FASEB BioAdvances 2020;2(8):453-463
Liver lymphatic drainage patterns follow segmental anatomy in a murine model.
Frenkel NC, Poghosyan S, Verheem A, Padera TP, Rinkes IHMB, Kranenburg O, Hagendoorn J
Scientific reports 2020 Dec 11;10(1):21808
Scientific reports 2020 Dec 11;10(1):21808
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Dobie R, Wilson-Kanamori JR, Henderson BEP, Smith JR, Matchett KP, Portman JR, Wallenborg K, Picelli S, Zagorska A, Pendem SV, Hudson TE, Wu MM, Budas GR, Breckenridge DG, Harrison EM, Mole DJ, Wigmore SJ, Ramachandran P, Ponting CP, Teichmann SA, Marioni JC, Henderson NC
Cell reports 2019 Nov 12;29(7):1832-1847.e8
Cell reports 2019 Nov 12;29(7):1832-1847.e8
Dietary Iron Overload Abrogates Chemically-Induced Liver Cirrhosis in Rats
Atarashi M, Izawa T, Mori M, Inai Y, Kuwamura M, Yamate J
Nutrients 2018;10(10):1400
Nutrients 2018;10(10):1400
Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer.
Preziosi M, Poddar M, Singh S, Monga SP
Gene expression 2018 Aug 22;18(3):209-219
Gene expression 2018 Aug 22;18(3):209-219
The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size
Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill M, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson T, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano L, Bouwmeester T, Cong F, Heim M, Forbes S, Ruffner H, Tchorz J
Nature Cell Biology 2016;18(5):467-479
Nature Cell Biology 2016;18(5):467-479
Alcohol Facilitates HCV RNA Replication Via Up‐Regulation of miR‐122 Expression and Inhibition of Cyclin G1 in Human Hepatoma Cells
Hou W, Bukong T, Kodys K, Szabo G
Alcoholism: Clinical and Experimental Research 2012;37(4):599-608
Alcoholism: Clinical and Experimental Research 2012;37(4):599-608
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human liver and endometrium tissues using HPA009128 antibody. Corresponding CYP2E1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
