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- References [22]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 14342-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14342-1-AP, RRID:AB_2092930
- Product name
- DIAPH3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DIAPH3 antibody (Cat. #14342-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of a cisplatin resistant-based prognostic immune related gene signature in MIBC.
Formin-mediated nuclear actin at androgen receptors promotes transcription.
The pan-cancer analysis identified DIAPH3 as a diagnostic biomarker of clinical cancer.
mDia formins form hetero-oligomers and cooperatively maintain murine hematopoiesis.
The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells.
TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis.
DIAPH3 is a prognostic biomarker and inhibit colorectal cancer progression through maintaining EGFR degradation.
Correction: Generation of stress fibers through myosin-driven reorganization of the actin cortex.
Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate.
Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice.
Nonredundant roles of DIAPHs in primary ciliogenesis.
Generation of stress fibers through myosin-driven reorganization of the actin cortex.
Membrane skeleton modulates erythroid proteome remodeling and organelle clearance.
Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres.
Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2).
Formin-dependent TGF-β signaling for epithelial to mesenchymal transition.
Actomyosin stress fiber subtypes have unique viscoelastic properties and roles in tension generation.
mDia2 and CXCL12/CXCR4 chemokine signaling intersect to drive tumor cell amoeboid morphological transitions.
APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions.
An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids.
The formin FMNL3 is a cytoskeletal regulator of angiogenesis.
Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation.
Wu Y, Xu Z, Fu G, Chen X, Tian J, Cai H, Jiang P, Jin B
Translational oncology 2024 Jun;44:101942
Translational oncology 2024 Jun;44:101942
Formin-mediated nuclear actin at androgen receptors promotes transcription.
Knerr J, Werner R, Schwan C, Wang H, Gebhardt P, Grötsch H, Caliebe A, Spielmann M, Holterhus PM, Grosse R, Hornig NC
Nature 2023 May;617(7961):616-622
Nature 2023 May;617(7961):616-622
The pan-cancer analysis identified DIAPH3 as a diagnostic biomarker of clinical cancer.
Chen X, Xie L, Qiao K, Zhu X, Ren J, Tan Y
Aging 2023 Jan 5;15(3):689-704
Aging 2023 Jan 5;15(3):689-704
mDia formins form hetero-oligomers and cooperatively maintain murine hematopoiesis.
Li Z, Su M, Xie X, Wang P, Bi H, Li E, Ren K, Dong L, Lv Z, Ma X, Liu Y, Zhao B, Peng Y, Liu J, Liu L, Yang J, Ji P, Mei Y
PLoS genetics 2023 Dec;19(12):e1011084
PLoS genetics 2023 Dec;19(12):e1011084
The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells.
Becker KN, Pettee KM, Sugrue A, Reinard KA, Schroeder JL, Eisenmann KM
Cells 2022 May 5;11(9)
Cells 2022 May 5;11(9)
TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis.
Huang Q, Wu D, Zhao J, Yan Z, Chen L, Guo S, Wang D, Yuan C, Wang Y, Liu X, Xing J
The EMBO journal 2022 Jun 1;41(11):e110324
The EMBO journal 2022 Jun 1;41(11):e110324
DIAPH3 is a prognostic biomarker and inhibit colorectal cancer progression through maintaining EGFR degradation.
Huang R, Wu C, Wen J, Yu J, Zhu H, Yu J, Zou Z
Cancer medicine 2022 Dec;11(23):4688-4702
Cancer medicine 2022 Dec;11(23):4688-4702
Correction: Generation of stress fibers through myosin-driven reorganization of the actin cortex.
Lehtimäki JI, Rajakylä EK, Tojkander S, Lappalainen P
eLife 2022 Apr 20;11
eLife 2022 Apr 20;11
Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate.
Wu YO, Bryant AT, Nelson NT, Madey AG, Fernandes GF, Goodson HV
PloS one 2021;16(12):e0260401
PloS one 2021;16(12):e0260401
Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice.
Majmundar AJ, Buerger F, Forbes TA, Klämbt V, Schneider R, Deutsch K, Kitzler TM, Howden SE, Scurr M, Tan KS, Krzeminski M, Widmeier E, Braun DA, Lai E, Ullah I, Amar A, Kolb A, Eddy K, Chen CH, Salmanullah D, Dai R, Nakayama M, Ottlewski I, Kolvenbach CM, Onuchic-Whitford AC, Mao Y, Mann N, Nabhan MM, Rosen S, Forman-Kay JD, Soliman NA, Heilos A, Kain R, Aufricht C, Mane S, Lifton RP, Shril S, Little MH, Hildebrandt F
Science advances 2021 Jan;7(1)
Science advances 2021 Jan;7(1)
Nonredundant roles of DIAPHs in primary ciliogenesis.
Palander O, Lam A, Collins RF, Moraes TJ, Trimble WS
The Journal of biological chemistry 2021 Jan-Jun;296:100680
The Journal of biological chemistry 2021 Jan-Jun;296:100680
Generation of stress fibers through myosin-driven reorganization of the actin cortex.
Lehtimäki JI, Rajakylä EK, Tojkander S, Lappalainen P
eLife 2021 Jan 28;10
eLife 2021 Jan 28;10
Membrane skeleton modulates erythroid proteome remodeling and organelle clearance.
Liu Y, Mei Y, Han X, Korobova FV, Prado MA, Yang J, Peng Z, Paulo JA, Gygi SP, Finley D, Ji P
Blood 2021 Jan 21;137(3):398-409
Blood 2021 Jan 21;137(3):398-409
Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres.
Pettee KM, Becker KN, Alberts AS, Reinard KA, Schroeder JL, Eisenmann KM
Cancers 2019 Mar 20;11(3)
Cancers 2019 Mar 20;11(3)
Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2).
Dvorak KM, Pettee KM, Rubinic-Minotti K, Su R, Nestor-Kalinoski A, Eisenmann KM
PloS one 2018;13(3):e0195278
PloS one 2018;13(3):e0195278
Formin-dependent TGF-β signaling for epithelial to mesenchymal transition.
Rana MK, Aloisio FM, Choi C, Barber DL
Molecular biology of the cell 2018 Jun 15;29(12):1465-1475
Molecular biology of the cell 2018 Jun 15;29(12):1465-1475
Actomyosin stress fiber subtypes have unique viscoelastic properties and roles in tension generation.
Lee S, Kassianidou E, Kumar S
Molecular biology of the cell 2018 Aug 8;29(16):1992-2004
Molecular biology of the cell 2018 Aug 8;29(16):1992-2004
mDia2 and CXCL12/CXCR4 chemokine signaling intersect to drive tumor cell amoeboid morphological transitions.
Wyse MM, Goicoechea S, Garcia-Mata R, Nestor-Kalinoski AL, Eisenmann KM
Biochemical and biophysical research communications 2017 Mar 4;484(2):255-261
Biochemical and biophysical research communications 2017 Mar 4;484(2):255-261
APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions.
Castelblanco E, Zafon C, Maravall J, Gallel P, Martinez M, Capel I, Bella MR, Halperin I, Temprana J, Iglesias C, Puig-Domingo M, Robledo M, Matias-Guiu X, Mauricio D
Thyroid : official journal of the American Thyroid Association 2017 Jan;27(1):59-66
Thyroid : official journal of the American Thyroid Association 2017 Jan;27(1):59-66
An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids.
Pettee KM, Dvorak KM, Nestor-Kalinoski AL, Eisenmann KM
PloS one 2014;9(2):e90371
PloS one 2014;9(2):e90371
The formin FMNL3 is a cytoskeletal regulator of angiogenesis.
Hetheridge C, Scott AN, Swain RK, Copeland JW, Higgs HN, Bicknell R, Mellor H
Journal of cell science 2012 Mar 15;125(Pt 6):1420-8
Journal of cell science 2012 Mar 15;125(Pt 6):1420-8
Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation.
Stastna J, Pan X, Wang H, Kollmannsperger A, Kutscheidt S, Lohmann V, Grosse R, Fackler OT
Cell research 2012 Apr;22(4):728-45
Cell research 2012 Apr;22(4):728-45
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14342-1-AP(DIAPH3 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DIAPH3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DIAPH3. This antibody recognizes human antigen. The DIAPH3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
