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- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 14761-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14761-1-AP, RRID:AB_1939806
- Product name
- WRAP53 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated WRAP53 antibody (Cat. #14761-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Highly efficient identification of nucleocytoplasmic O-glycosylation by the TurboID-based proximity labeling method in living cells.
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly.
[Effect of WRAP53 β Targeted Co-Inhibitory Pathways Based on Comprehensive Bioinformatics Analysis in Treating Squamous Cell Carcinoma of the Head and Neck].
RNF8 ubiquitinates RecQL4 and promotes its dissociation from DNA double strand breaks.
Suppression of TCAB1 expression induced cellular senescence by lessening proteasomal degradation of p21 in cancer cells.
Observation of processive telomerase catalysis using high-resolution optical tweezers.
Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism.
Phosphorylation of the Cajal body protein WRAP53β by ATM promotes its involvement in the DNA damage response.
Overexpression of WRAP53 is associated with development and progression of esophageal squamous cell carcinoma.
The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.
Long Y, Li Z, Wang L, Ao X, Zhang Z, Chen Q, Zhu D, Liu X, Liu R, Chen B, Zhu H, Su Y
Biotechnology journal 2024 Jan;19(1):e2300090
Biotechnology journal 2024 Jan;19(1):e2300090
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Zhu Y, Sun W, Jiang X, Bai R, Luo Y, Gao Y, Li S, Huang Z, Gong Y, Xie C
PloS one 2023;18(1):e0281132
PloS one 2023;18(1):e0281132
TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly.
Klump BM, Perez GI, Patrick EM, Adams-Boone K, Cohen SB, Han L, Yu K, Schmidt JC
Cell reports 2023 Jun 27;42(6):112577
Cell reports 2023 Jun 27;42(6):112577
[Effect of WRAP53 β Targeted Co-Inhibitory Pathways Based on Comprehensive Bioinformatics Analysis in Treating Squamous Cell Carcinoma of the Head and Neck].
Yao YF, Liu W, Zhou ML, Qiu TL, Wang K
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2022 May;53(3):457-465
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2022 May;53(3):457-465
RNF8 ubiquitinates RecQL4 and promotes its dissociation from DNA double strand breaks.
Tan Q, Niu K, Zhu Y, Chen Z, Li Y, Li M, Wei D, Balajee AS, Fang H, Zhao Y
Oncogenesis 2021 Mar 5;10(3):24
Oncogenesis 2021 Mar 5;10(3):24
Suppression of TCAB1 expression induced cellular senescence by lessening proteasomal degradation of p21 in cancer cells.
Niu J, Gao RQ, Cui MT, Zhang CG, Li ST, Cheng S, Ding W
Cancer cell international 2021 Jan 7;21(1):26
Cancer cell international 2021 Jan 7;21(1):26
Observation of processive telomerase catalysis using high-resolution optical tweezers.
Patrick EM, Slivka JD, Payne B, Comstock MJ, Schmidt JC
Nature chemical biology 2020 Jul;16(7):801-809
Nature chemical biology 2020 Jul;16(7):801-809
Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism.
Pan XH, Chen YH, Yang YK, Zhang XJ, Lin QK, Li ZA, Cai XM, Pang RQ, Zhu XQ, Ruan GP
Aging 2019 Jan 23;11(2):590-614
Aging 2019 Jan 23;11(2):590-614
Phosphorylation of the Cajal body protein WRAP53β by ATM promotes its involvement in the DNA damage response.
Coucoravas C, Dhanjal S, Henriksson S, Böhm S, Farnebo M
RNA biology 2017 Jun 3;14(6):804-813
RNA biology 2017 Jun 3;14(6):804-813
Overexpression of WRAP53 is associated with development and progression of esophageal squamous cell carcinoma.
Rao X, Huang D, Sui X, Liu G, Song X, Xie J, Huang D
PloS one 2014;9(3):e91670
PloS one 2014;9(3):e91670
The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.
Henriksson S, Rassoolzadeh H, Hedström E, Coucoravas C, Julner A, Goldstein M, Imreh G, Zhivotovsky B, Kastan MB, Helleday T, Farnebo M
Genes & development 2014 Dec 15;28(24):2726-38
Genes & development 2014 Dec 15;28(24):2726-38
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human kidney tissue were subjected to SDS PAGE followed by western blot with 14761-1-AP(WRAP53 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 14761-1-AP(WRAP53 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The WRAP53 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human WRAP53. This antibody recognizes human,mouse,rat antigen. The WRAP53 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
