51011-1-AP

antibody from Proteintech Group

Targeting: LYVE1 LYVE-1, XLKD1

Provider product page for 51011-1-AP

Western blot

ELISA

Antibody data

Antibody Data
Antigen structure
References [18]
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Validations
Western blot [1]

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Product number: 51011-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#51011-1-AP, RRID:AB_2138655
Product name: LYVE1 antibody
Antibody type: Polyclonal
Description: LYVE1 antibody (Cat. #51011-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

LYVE1 protein structure - 51011-1-AP shown in red.

Submitted references Lingguizhugan decoction improves cognitive impairment in APP/PS1 mice by promoting meningeal lymphatic drainage based on fatty acid degradation pathway.

Shen Z, Wu M, Sun S, Ling Y, Chen X, Zhang J, Zhou X, Zhou C
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120748

The regulation of lymphatic valve formation promotes lymphatic drainage to reduce atherosclerotic plaques: A novel mechanism of anti-atherosclerosis by Gualou-Xiebai.

Liu J, Li Z, Sun X, Zhu L, Bao Y, Liu Z, Xu Y, Xia X, Zhao W, Zhang Y, Zhou A, Wu H
Journal of ethnopharmacology 2026 Feb 28;357:120937

Natural progression of meningeal lymphatic dysfunction in APP/PS1 mice creates a critical window for Alzheimer's disease intervention.

Shen Z, Zhou X, He L, Wu M, Zhou C
Turkish journal of medical sciences 2025;55(6):1576-1583

Tumor cell-derived hyaluronan fragments induce endocytosis of S1PR1 to promote lymphangiogenesis through LYVE-1-Src pathway.

Jiang M, Chen D, Xu Z, Liu Y, Yang C, Zhang G, Guo Q, Gao F, He Y, Du Y
Journal of Cancer 2025;16(5):1466-1478

Pachymic acid alleviates secondary lymphedema through the modulation of EETs level and the inhibition of lymphatic fibrosis.

Fang X, Xiao T, Li Y, Qian D, He C, Hong W, Zhu L, Wang D, Meng X, Liu X
International immunopharmacology 2025 Sep 23;162:115066

Targeting VSIG4(+) tissue-resident macrophages enhances T cell cytotoxicity and immunotherapy efficacy in cancer.

Ma Z, Wang Y, Wang W, Wei C, Liu Z, Li Z, Ye Y, Mao Y, Yuan Y, Huang Z, Zhang J, Cao Y, Mao X, Zhang Y, Jin X, Yin J, Li G, Zheng L, Liu Z, Li X, Liang X, Liu Z
Developmental cell 2025 Oct 6;60(19):2594-2610.e5

HOXA9 drives lymphatic metastasis by activating the c-MYC-glycolysis-lactate axis in gastric cancer.

Lu T, Shen G, Huang T, Mao X, He J, Hu Y
Journal of translational medicine 2025 Nov 17;23(1):1294

FN1 shapes the behavior of papillary thyroid carcinoma through alternative splicing of EDB region.

Liu M, Chen P, Wei B, Tan HL, Zhao YX, Ai L, Li N, Jiang YK, Lin J, Li SJ, Chang S
Scientific reports 2025 Jan 2;15(1):327

Linagliptin's impact on lymphatic barrier and lymphangiogenesis in oral cancer with high glucose.

Wang H, She X, Xu Q, Zhou X, Tang Q, Wei H, Huang T, Liang F
Oral diseases 2024 Oct;30(7):4195-4208

Integrative metabolomics and proteomics reveal the effect and mechanism of Zi Qi decoction on alleviating liver fibrosis.

Chen X, Wang Y, Dou X, Wan J, Zhou J, Li T, Yu J, Ye F
Scientific reports 2024 Nov 22;14(1):28943

N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.

Ding P, Wu H, Wu J, Li T, He J, Ju Y, Liu Y, Li F, Deng H, Gu R, Zhang L, Guo H, Tian Y, Yang P, Meng N, Li X, Guo Z, Meng L, Zhao Q
Oncogene 2024 Aug;43(34):2548-2563

Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy.

Luo Q, Dong Z, Xie W, Fu X, Lin L, Zeng Q, Chen Y, Ye G, Chen M, Hu H, Wang L, Xie Y, Cai W
Cell reports 2023 May 30;42(5):112437

Endothelial Microparticle-Mediated Transfer of microRNA-19b Inhibits the Function and Distribution of Lymphatic Vessels in Atherosclerotic Mice.

Yu SR, Cui YX, Song ZQ, Li SF, Zhang CY, Song JX, Chen H
Frontiers in physiology 2022;13:850298

Loss of GNE Predicts Lymph Node Metastasis in Early Gastric Cancer.

Guo X, Gu J, Xue A, Song S, Liu B, Gao X, Gu J, Chang L, Ruan Y
Cells 2022 Nov 16;11(22)

Clostridium butyricum alleviates dextran sulfate sodium-induced experimental colitis and promotes intestinal lymphatic vessel regeneration in mice.

Chen X, Ma L, Liu X, Wang J, Li Y, Xie Q, Liang J
Annals of translational medicine 2022 Mar;10(6):341

Heteronemin Suppresses Lymphangiogenesis through ARF-1 and MMP-9/VE-Cadherin/Vimentin.

Chen HL, Su YC, Chen HC, Su JH, Wu CY, Wang SW, Lin IP, Chen CY, Lee CH
Biomedicines 2021 Aug 29;9(9)

PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing.

Liang X, Chen W, Shi H, Gu X, Li Y, Qi Y, Xu K, Zhao A, Liu J
Cell death & disease 2018 May 1;9(5):569

Establishment and characterization of a human lymphatic endothelial cell line.

Nakamura R, Sugano M, Sone Y, Sakabe K, Itoh T, Kiyono M
Biological & pharmaceutical bulletin 2014;37(4):683-7

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The LYVE1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LYVE1. This antibody recognizes human antigen. The LYVE1 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 51011-1-AP.pdf

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