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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- ABIN955391 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tubulin, beta 2B (TUBB2B) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1 mg
Submitted references Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria.
Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of beta-tubulin at Cys 12 and suppression of microtubule dynamics.
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
Beta-tubulin isotype classes II and V expression patterns in nonsmall cell lung carcinomas.
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
Jaglin XH, Poirier K, Saillour Y, Buhler E, Tian G, Bahi-Buisson N, Fallet-Bianco C, Phan-Dinh-Tuy F, Kong XP, Bomont P, Castelnau-Ptakhine L, Odent S, Loget P, Kossorotoff M, Snoeck I, Plessis G, Parent P, Beldjord C, Cardoso C, Represa A, Flint J, Keays DA, Cowan NJ, Chelly J
Nature genetics 2009 Jun;41(6):746-52
Nature genetics 2009 Jun;41(6):746-52
Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of beta-tubulin at Cys 12 and suppression of microtubule dynamics.
Xu W, Xi B, Wu J, An H, Zhu J, Abassi Y, Feinstein SC, Gaylord M, Geng B, Yan H, Fan W, Sui M, Wang X, Xu X
Molecular cancer therapeutics 2009 Dec;8(12):3318-30
Molecular cancer therapeutics 2009 Dec;8(12):3318-30
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
Martins-de-Souza D, Gattaz WF, Schmitt A, Rewerts C, Maccarrone G, Dias-Neto E, Turck CW
European archives of psychiatry and clinical neuroscience 2009 Apr;259(3):151-63
European archives of psychiatry and clinical neuroscience 2009 Apr;259(3):151-63
Beta-tubulin isotype classes II and V expression patterns in nonsmall cell lung carcinomas.
Cucchiarelli V, Hiser L, Smith H, Frankfurter A, Spano A, Correia JJ, Lobert S
Cell motility and the cytoskeleton 2008 Aug;65(8):675-85
Cell motility and the cytoskeleton 2008 Aug;65(8):675-85
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
Lamesch P, Li N, Milstein S, Fan C, Hao T, Szabo G, Hu Z, Venkatesan K, Bethel G, Martin P, Rogers J, Lawlor S, McLaren S, Dricot A, Borick H, Cusick ME, Vandenhaute J, Dunham I, Hill DE, Vidal M
Genomics 2007 Mar;89(3):307-15
Genomics 2007 Mar;89(3):307-15
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- TUBB2B Antibody (N-term) (AP54415PU-N) western blot analysis in HepG2,Hela,MDA-MB231 cell line lysates (35 μg/lane). This demonstrates the TUBB2B antibody detected the TUBB2B protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of TUBB2B Antibody (N-term) (AP54415PU-N) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- TUBB2B Antibody (N-term) (AP54415PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TUBB2B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
