Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 21017-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21017-1-AP, RRID:AB_10696447
- Product name
- KLF5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KLF5 antibody (Cat. #21017-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Evaluation of Barrier Functions in Human iPSC-Derived Intestinal Epithelium.
A Weighted Gene Co-Expression Network Analysis-Derived Prognostic Model for Predicting Prognosis and Immune Infiltration in Gastric Cancer.
Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.
CircATRNL1 protects against osteoarthritis by targeting miR-153-3p and KLF5.
An inhibitor of Krüppel-like factor 5 suppresses peritoneal fibrosis in mice.
Curcumol inhibits KLF5-dependent angiogenesis by blocking the ROS/ERK signaling in liver sinusoidal endothelial cells.
Transcription factor Kruppel-like factor 5 positively regulates the expression of AarF domain containing kinase 4.
KLF5 Is Crucial for Androgen-AR Signaling to Transactivate Genes and Promote Cell Proliferation in Prostate Cancer Cells.
Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.
mircroRNA-152 prevents the malignant progression of atherosclerosis via down-regulation of KLF5.
The long non-coding RNA TUG1-miR-9a-5p axis contributes to ischemic injuries by promoting cardiomyocyte apoptosis via targeting KLF5.
Retinoic acid promotes barrier functions in human iPSC-derived intestinal epithelial monolayers.
KLF5 promotes the tumorigenesis and metastatic potential of thyroid cancer cells through the NF-κB signaling pathway.
miR-448-3p controls intracranial aneurysm by regulating KLF5 expression.
Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression.
miR-20a-5p promotes adipogenic differentiation of murine bone marrow stromal cells via targeting Kruppel-like factor 3.
DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma.
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
Yamada S, Kanda Y
Methods in molecular biology (Clifton, N.J.) 2021;2367:27-35
Methods in molecular biology (Clifton, N.J.) 2021;2367:27-35
A Weighted Gene Co-Expression Network Analysis-Derived Prognostic Model for Predicting Prognosis and Immune Infiltration in Gastric Cancer.
Chen Q, Tan Y, Zhang C, Zhang Z, Pan S, An W, Xu H
Frontiers in oncology 2021;11:554779
Frontiers in oncology 2021;11:554779
Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.
Gao L, Yang X, Liang B, Jia Y, Tan S, Chen A, Cao P, Zhang Z, Zheng S, Sun L, Zhang F, Shao J
Toxicology 2021 Mar 30;452:152707
Toxicology 2021 Mar 30;452:152707
CircATRNL1 protects against osteoarthritis by targeting miR-153-3p and KLF5.
Wang KF, Shi ZW, Dong DM
International immunopharmacology 2021 Jul;96:107704
International immunopharmacology 2021 Jul;96:107704
An inhibitor of Krüppel-like factor 5 suppresses peritoneal fibrosis in mice.
Muta K, Nakazawa Y, Obata Y, Inoue H, Torigoe K, Nakazawa M, Abe K, Furusu A, Miyazaki M, Yamamoto K, Koji T, Nishino T
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2021 Jul;41(4):394-403
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2021 Jul;41(4):394-403
Curcumol inhibits KLF5-dependent angiogenesis by blocking the ROS/ERK signaling in liver sinusoidal endothelial cells.
Gao L, Yang X, Li Y, Wang Z, Wang S, Tan S, Chen A, Cao P, Shao J, Zhang Z, Zhang F, Zheng S
Life sciences 2021 Jan 1;264:118696
Life sciences 2021 Jan 1;264:118696
Transcription factor Kruppel-like factor 5 positively regulates the expression of AarF domain containing kinase 4.
Chen X, Liu S, Chen J, Wang X, Zhou G
Molecular biology reports 2020 Nov;47(11):8419-8427
Molecular biology reports 2020 Nov;47(11):8419-8427
KLF5 Is Crucial for Androgen-AR Signaling to Transactivate Genes and Promote Cell Proliferation in Prostate Cancer Cells.
Li J, Zhang B, Liu M, Fu X, Ci X, A J, Fu C, Dong G, Wu R, Zhang Z, Fu L, Dong JT
Cancers 2020 Mar 21;12(3)
Cancers 2020 Mar 21;12(3)
Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.
Li Y, Kong R, Chen H, Zhao Z, Li L, Li J, Hu J, Zhang G, Pan S, Wang Y, Wang G, Chen H, Sun B
Aging 2019 Jul 21;11(14):5035-5057
Aging 2019 Jul 21;11(14):5035-5057
mircroRNA-152 prevents the malignant progression of atherosclerosis via down-regulation of KLF5.
Wang W, Zhang Y, Wang L, Li J, Li Y, Yang X, Wu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2409-2414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2409-2414
The long non-coding RNA TUG1-miR-9a-5p axis contributes to ischemic injuries by promoting cardiomyocyte apoptosis via targeting KLF5.
Yang D, Yu J, Liu HB, Yan XQ, Hu J, Yu Y, Guo J, Yuan Y, Du ZM
Cell death & disease 2019 Dec 2;10(12):908
Cell death & disease 2019 Dec 2;10(12):908
Retinoic acid promotes barrier functions in human iPSC-derived intestinal epithelial monolayers.
Yamada S, Kanda Y
Journal of pharmacological sciences 2019 Aug;140(4):337-344
Journal of pharmacological sciences 2019 Aug;140(4):337-344
KLF5 promotes the tumorigenesis and metastatic potential of thyroid cancer cells through the NF-κB signaling pathway.
Ma Y, Wang Q, Liu F, Ma X, Wu L, Guo F, Zhao S, Huang F, Qin G
Oncology reports 2018 Nov;40(5):2608-2618
Oncology reports 2018 Nov;40(5):2608-2618
miR-448-3p controls intracranial aneurysm by regulating KLF5 expression.
Zhang JZ, Chen D, Lv LQ, Xu Z, Li YM, Wang JY, Han KW, Yu MK, Huang CG, Hou LJ
Biochemical and biophysical research communications 2018 Nov 10;505(4):1211-1215
Biochemical and biophysical research communications 2018 Nov 10;505(4):1211-1215
Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression.
Zhang D, Lin J, Chao Y, Zhang L, Jin L, Li N, He R, Ma B, Zhao W, Han C
Journal of experimental & clinical cancer research : CR 2018 Jul 28;37(1):176
Journal of experimental & clinical cancer research : CR 2018 Jul 28;37(1):176
miR-20a-5p promotes adipogenic differentiation of murine bone marrow stromal cells via targeting Kruppel-like factor 3.
Zhu E, Zhang J, Zhou J, Yuan H, Zhao W, Wang B
Journal of molecular endocrinology 2018 Apr;60(3):225-237
Journal of molecular endocrinology 2018 Apr;60(3):225-237
DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma.
Fu RJ, He W, Wang XB, Li L, Zhao HB, Liu XY, Pang Z, Chen GQ, Huang L, Zhao KW
Cell death & disease 2017 Jul 27;8(7):e2952
Cell death & disease 2017 Jul 27;8(7):e2952
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Wei X, Ye J, Shang Y, Chen H, Liu S, Liu L, Wang R
Oncotarget 2017 Dec 12;8(65):109301-109318
Oncotarget 2017 Dec 12;8(65):109301-109318
ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
Ji S, Qin Y, Shi S, Liu X, Hu H, Zhou H, Gao J, Zhang B, Xu W, Liu J, Liang D, Liu L, Liu C, Long J, Zhou H, Chiao PJ, Xu J, Ni Q, Gao D, Yu X
Cell research 2015 May;25(5):561-73
Cell research 2015 May;25(5):561-73
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KLF5 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human KLF5. This antibody recognizes human,mouse,rat antigen. The KLF5 antibody has been validated for the following applications: ELISA, WB analysis.