HPA040398

antibody from Atlas Antibodies

Targeting: KLF5 BTEB2, CKLF, IKLF

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Chromatin Immunoprecipitation (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA040398

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA040398, RRID:AB_10673267

Product name

Anti-KLF5

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human KLF5, Gene description: Kruppel-like factor 5 (intestinal), Alternative Gene Names: BTEB2, CKLF, IKLF, Validated applications: IHC, ChIP, ICC, Uniprot ID: Q13887, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Genome-Wide Profiling Reveals HPV Integration Pattern and Activated Carcinogenic Pathways in Penile Squamous Cell Carcinoma

Huang K, Guo S, Li Y, Zhang X, Chen D, Spiess P, Li Z, Deng C, Chen J, Zhou Q, Hu Z, Ma X, Jin J, Cao Y, Luo J, Wang X, Zhou F, Liu R, Han H
Cancers 2021;13(23):6104

---

Prognostic Value and Function of KLF5 in Papillary Thyroid Cancer

Pratheeshkumar P, Siraj A, Divya S, Parvathareddy S, Siraj S, Diaz R, Begum R, Al-Sobhi S, Al-Dayel F, Al-Kuraya K
Cancers 2021;13(2):185

---

Krupple-Like Factor 5 is a Potential Therapeutic Target and Prognostic Marker in Epithelial Ovarian Cancer

Siraj A, Pratheeshkumar P, Divya S, Parvathareddy S, Alobaisi K, Thangavel S, Siraj S, Al-Badawi I, Al-Dayel F, Al-Kuraya K
Frontiers in Pharmacology 2020;11

---

DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma

Fu R, He W, Wang X, Li L, Zhao H, Liu X, Pang Z, Chen G, Huang L, Zhao K
Cell Death & Disease 2017;8(7):e2952-e2952

---

Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality

Zimmerlin L, Park T, Huo J, Verma K, Pather S, Talbot C, Agarwal J, Steppan D, Zhang Y, Considine M, Guo H, Zhong X, Gutierrez C, Cope L, Canto-Soler M, Friedman A, Baylin S, Zambidis E
Development 2016;143(23):4368-4380

Chromatin Immunoprecipitation

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

ChIP-Exo-Seq composite graph for Anti-KLF5 (HPA040398, Lot 000046764) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.