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- References [14]
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- Product number
- 15979-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15979-1-AP, RRID:AB_2270820
- Product name
- Spermine synthase antibody
- Antibody type
- Polyclonal
- Description
- Spermine synthase antibody (Cat. #15979-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Effects of spermine on osteoblasts during iron deficiency in vitro and in vivo during chronic kidney disease.
The RET inhibitor pralsetinib suppresses TMZ-resistant glioma growth by regulating spermine production.
Multi-omics analysis of polyamine metabolism implicates NT5E/CD73 in the progression of pancreatic cancer.
Oleanolic acid alleviates ulcerative colitis by remodeling Th17 cells via targeting HSP90β-ODC1 pathway-mediated polyamine synthesis.
Natural Product Quercetin-3-methyl ether Promotes Colorectal Cancer Cell Apoptosis by Downregulating Intracellular Polyamine Signaling.
Predicting lung adenocarcinoma prognosis, immune escape, and pharmacomic profile from arginine and proline-related genes.
Inhibition of Polyamine Catabolism Reduces Cellular Senescence.
A search for acrolein scavengers among food components.
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Magnesium Supplementation Attenuates Ultraviolet-B-Induced Damage Mediated through Elevation of Polyamine Production in Human HaCaT Keratinocytes.
Correlation of polyamines, acrolein-conjugated lysine and polyamine metabolic enzyme levels with age in human liver.
Proteomic analysis revealed different responses to hypergravity of soleus and extensor digitorum longus muscles in mice.
Spermidine/spermine-N(1)-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
Changes in the proteomic profile during the differential polarization status of the human monocyte-derived macrophage THP-1 cell line.
Miller C, Segvich DM, Wanner J, Mahmood H, Kirschner KM, Matz JA, Santangelo S, Wallace JM, Clinkenbeard EL
Bone 2026 Jul;208:117867
Bone 2026 Jul;208:117867
The RET inhibitor pralsetinib suppresses TMZ-resistant glioma growth by regulating spermine production.
Ma L, Gong H, Sun W, Deng J, Zhang Q, Niu J, Sun H, Han X, Du T, Xue N, Ji M, Liu Q
Frontiers in pharmacology 2025;16:1671798
Frontiers in pharmacology 2025;16:1671798
Multi-omics analysis of polyamine metabolism implicates NT5E/CD73 in the progression of pancreatic cancer.
Zhang E, Ding X, Zhang J, Liu W, Liu G, Li M, Liu X, Wang Y, Zhang F, Li B, Zhu Y, Yan Y, Liu J, Wang Y, Tian X, Ma Y, Yang Y
Cancer letters 2025 Oct 10;630:217887
Cancer letters 2025 Oct 10;630:217887
Oleanolic acid alleviates ulcerative colitis by remodeling Th17 cells via targeting HSP90β-ODC1 pathway-mediated polyamine synthesis.
Yuan Y, Tian Y, Zhao Z, Gui Y, Wang J, Zhu F, Xue G, Gao F, Liu Y, Fan H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157441
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157441
Natural Product Quercetin-3-methyl ether Promotes Colorectal Cancer Cell Apoptosis by Downregulating Intracellular Polyamine Signaling.
Zeng J, Zhang Y, Fang Y, Lian J, Zhang H, Zhang S, Lin B, Ye Z, Li C, Qiu X, Liang Y
International journal of medical sciences 2024;21(5):904-913
International journal of medical sciences 2024;21(5):904-913
Predicting lung adenocarcinoma prognosis, immune escape, and pharmacomic profile from arginine and proline-related genes.
Wang Z, Zhang J, Shi S, Ma H, Wang D, Zuo C, Zhang Q, Lian C
Scientific reports 2023 Sep 14;13(1):15198
Scientific reports 2023 Sep 14;13(1):15198
Inhibition of Polyamine Catabolism Reduces Cellular Senescence.
Uemura T, Matsunaga M, Yokota Y, Takao K, Furuchi T
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
A search for acrolein scavengers among food components.
Uemura T, Uchida M, Nakamura M, Shimekake M, Sakamoto A, Terui Y, Higashi K, Ishii I, Kashiwagi K, Igarashi K
Amino acids 2023 Apr;55(4):509-518
Amino acids 2023 Apr;55(4):509-518
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Halloran KM, Stenhouse C, Moses RM, Seo H, Johnson GA, Wu G, Bazer FW
Biology of reproduction 2022 May 17;106(5):865-878
Biology of reproduction 2022 May 17;106(5):865-878
Magnesium Supplementation Attenuates Ultraviolet-B-Induced Damage Mediated through Elevation of Polyamine Production in Human HaCaT Keratinocytes.
Shu S, Kobayashi M, Marunaka K, Yoshino Y, Goto M, Katsuta Y, Ikari A
Cells 2022 Jul 22;11(15)
Cells 2022 Jul 22;11(15)
Correlation of polyamines, acrolein-conjugated lysine and polyamine metabolic enzyme levels with age in human liver.
Uemura T, Akasaka Y, Ikegaya H
Heliyon 2020 Sep;6(9):e05031
Heliyon 2020 Sep;6(9):e05031
Proteomic analysis revealed different responses to hypergravity of soleus and extensor digitorum longus muscles in mice.
Ohira T, Ino Y, Nakai Y, Morita H, Kimura A, Kurata Y, Kagawa H, Kimura M, Egashira K, Moriya S, Hiramatsu K, Kawakita M, Kimura Y, Hirano H
Journal of proteomics 2020 Apr 15;217:103686
Journal of proteomics 2020 Apr 15;217:103686
Spermidine/spermine-N(1)-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
Sandusky-Beltran LA, Kovalenko A, Ma C, Calahatian JIT, Placides DS, Watler MD, Hunt JB, Darling AL, Baker JD, Blair LJ, Martin MD, Fontaine SN, Dickey CA, Lussier AL, Weeber EJ, Selenica MB, Nash KR, Gordon MN, Morgan D, Lee DC
Alzheimer's research & therapy 2019 Jun 29;11(1):58
Alzheimer's research & therapy 2019 Jun 29;11(1):58
Changes in the proteomic profile during the differential polarization status of the human monocyte-derived macrophage THP-1 cell line.
Zhang F, Liu H, Jiang G, Wang H, Wang X, Wang H, Fang R, Cai S, Du J
Proteomics 2015 Feb;15(4):773-86
Proteomics 2015 Feb;15(4):773-86
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Spermine synthase antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Spermine synthase. This antibody recognizes human,mouse,rat antigen. The Spermine synthase antibody has been validated for the following applications: ELISA, WB analysis.
