Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB228P-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human gp130 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human gp130 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R, rhIL-4 R, or rhIL-6 R is observed.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 28126
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer.
IL-6 regulates MCP-1, ICAM-1 and IL-6 expression in human myoblasts.
Larsen JV, Hansen M, Møller B, Madsen P, Scheller J, Nielsen M, Petersen CM
Molecular and cellular biology 2010 Sep;30(17):4175-87
Molecular and cellular biology 2010 Sep;30(17):4175-87
IL-6 regulates MCP-1, ICAM-1 and IL-6 expression in human myoblasts.
Marino M, Scuderi F, Provenzano C, Scheller J, Rose-John S, Bartoccioni E
Journal of neuroimmunology 2008 May 30;196(1-2):41-8
Journal of neuroimmunology 2008 May 30;196(1-2):41-8
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of gp130 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD3 epsilon APC-conjugated Monoclonal Antibody (Catalog # FAB100A) and either (A) Mouse Anti-Human gp130 PE-conjugated Monoclonal Antibody (Catalog # FAB228P) or (B) Mouse IgG1 Phycoerythrin Isotype Control (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.