67766-1-Ig

antibody from Proteintech Group

Targeting: IL6ST CD130, GP130, sGP130

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

67766-1-Ig

Provider

Proteintech Group

Product name

IL-6RB antibody

Antibody type

Monoclonal

Description

IL-6RB antibody (Cat. #67766-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: WB,ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1H7C5

Vial size

20ul, 150ul

References

Submitted references

Wei-Mi-Shu, a Stomach-Harmonizing Herbal Prescription, Alleviates Chronic Gastritis with Liver‑Stomach Disharmony by Modulating IL-6/STAT3 Signaling.

Zou X, Wei M, Jia S, Qi Y, Li H, Liu Y, Li J
Journal of inflammation research 2026;19:556234

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GPX1 expression promotes stemness and aggressiveness in myxoid liposarcomas.

Huergo C, Tornín J, Estupiñán O, Díez P, Gallego B, Gao J, Creskey M, Muradia G, González MV, Murillo D, Rey V, Martínez-Cruzado L, Menéndez ST, Rodríguez-Santamaría M, Blanco V, Quirós I, Sáinz RM, Rosu-Myles M, Lavoie JR, Rodríguez R
International journal of biological sciences 2025;21(13):5609-5627

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Hypomethylation of IL6ST promotes development of endometriosis by activating JAK2/STAT3 signaling pathway.

Hu Y, Chen H, Jin L, Chi X, Zhao J, Cao Q
PloS one 2025;20(1):e0317569

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Integrated transcriptomic and proteomic analyses identify the TLR2-CXCR4 axis as a regulator of endothelial cell migration under simulated microgravity.

Qin X, Wang R, Li C, Pan Y, Wang Y, Sun X
Frontiers in physiology 2025;16:1701338

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IL-6 signaling is required for the development and regeneration of ear cartilage in microtia.

Luan W, Fan S, Jiang H, Jiang D, Yang J, He L
Frontiers in cell and developmental biology 2025;13:1625058

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Genome-wide mapping of RNA-protein associations through sequencing.

Qi Z, Xue S, Chen J, Zhao W, Johnson K, Wen X, Charles Richard JL, Lin P, Zhong S
Nature biotechnology 2025 Sep 9;

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C/EBP β/AEP pathway mediates hippocampal mitochondrial damage in a mouse model of sepsis encephalopathy.

Shi Z, Peng Q, Sun S, Xiong M, Zhu X, Wang H, Liu S, Li Z, Wang L, Li G, Zhan L
International immunopharmacology 2025 Oct 10;163:115275

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Positive feedback loop of IGF2BP3/IL6ST/STAT3 facilitates malignant progression in colorectal cancer.

Liu P, Zhou X
Journal of translational medicine 2025 Nov 25;24(1)

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STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.

Yu W, Gui S, Peng L, Luo H, Xie J, Xiao J, Yilamu Y, Sun Y, Cai S, Cheng Z, Tao Z
Developmental cell 2025 Jun 23;60(12):1751-1767.e9

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BLOC1S1 Attenuates B. Melitensis 16M LPS-Triggered Autophagy by Spatial Confinement of TDP-43.

Wan S, Han M, Zhang M, Chen W, Xie F, Luo X, Wu W, Wang C, Yang D, Han B, Zhu H, Yu H, Li N, Hua J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e05635

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Targeted therapies of inflammatory diseases with intracellularly gelated macrophages in mice and rats.

Gao C, Wang Q, Ding Y, Kwong CHT, Liu J, Xie B, Wei J, Lee SMY, Mok GSP, Wang R
Nature communications 2024 Jan 6;15(1):328

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Construction of a prognostic model for triple-negative breast cancer based on immune-related genes, and associations between the tumor immune microenvironment and immunological therapy.

Zhu Y, Tao LF, Liu JY, Wang YX, Huang H, Jiang YN, Qian WF
Cancer medicine 2023 Jul;12(14):15704-15719

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Increased SPON1 promotes pancreatic ductal adenocarcinoma progression by enhancing IL-6 trans-signalling.

Huo Y, Yang J, Zheng J, Xu D, Yang M, Tao L, Yao H, Fu X, Yang J, Liu D, Hua R, Zhang J, Sun Y, Hu L, Liu W
Cell proliferation 2022 May;55(5):e13237