MAB228

antibody from R&D Systems

Targeting: IL6ST CD130, GP130, sGP130

Flow cytometry (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB228

Provider

R&D Systems

Product name

Anti-Human gp130 Monoclonal Antibody (Clone 28126)

Antibody type

Monoclonal

Antigen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human gp130 extracellular domain

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

500 µg

References

Submitted references

Granulocytes Are Unresponsive to IL-6 Due to an Absence of gp130.

Wilkinson AN, Gartlan KH, Kelly G, Samson LD, Olver SD, Avery J, Zomerdijk N, Tey SK, Lee JS, Vuckovic S, Hill GR
Journal of immunology (Baltimore, Md. : 1950) 2018 May 15;200(10):3547-3555

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Systematic validation of specific phenotypic markers for in vitro polarized human macrophages.

Ambarus CA, Krausz S, van Eijk M, Hamann J, Radstake TR, Reedquist KA, Tak PP, Baeten DL
Journal of immunological methods 2012 Jan 31;375(1-2):196-206

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Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells.

Ara T, Song L, Shimada H, Keshelava N, Russell HV, Metelitsa LS, Groshen SG, Seeger RC, DeClerck YA
Cancer research 2009 Jan 1;69(1):329-37

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Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells.

Erices A, Conget P, Rojas C, Minguell JJ
Experimental cell research 2002 Oct 15;280(1):24-32

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Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells.

Erices A, Conget P, Rojas C, Minguell JJ
Experimental cell research 2002 Oct 15;280(1):24-32