MAB2281

antibody from R&D Systems

Targeting: IL6ST CD130, GP130, sGP130

Western blot (Recommended by provider)

Antibody Data

Product number

MAB2281

Provider

R&D Systems

Product name

Anti-Human gp130 Monoclonal Antibody (Clone 29104)

Antibody type

Monoclonal

Antigen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human gp130 extracellular domain, Leu24-Glu619 (Glu619Asp)

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Antigen sequence

P40189


Isotype

IgG

Vial size

500 µg

References

Submitted references

IL-27 Modulates Chemokine Production in TNF-α -Stimulated Human Oral Epithelial Cells.

Hosokawa Y, Hosokawa I, Ozaki K, Matsuo T
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(3):1198-1206

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Trans-signaling is a dominant mechanism for the pathogenic actions of interleukin-6 in the brain.

Campbell IL, Erta M, Lim SL, Frausto R, May U, Rose-John S, Scheller J, Hidalgo J
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Feb 12;34(7):2503-13

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Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle.

Ammit AJ, Moir LM, Oliver BG, Hughes JM, Alkhouri H, Ge Q, Burgess JK, Black JL, Roth M
American journal of physiology. Lung cellular and molecular physiology 2007 Jan;292(1):L199-206