Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- ABIN1105846 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) antibody
- Antibody type
- Monoclonal
- Description
- Ion Exchange Chromatography.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- B-P8
- Vial size
- 0.2 mg
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references Long term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis.
A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor.
Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus.
Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130.
Identification of a gp130 cytokine receptor critical site involved in oncostatin M response.
A gp130 interleukin-6 transducer-dependent SCID model of human multiple myeloma.
Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex.
Interleukin-6: structure-function relationships.
Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties.
Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M.
Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein.
Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies.
Giese B, Au-Yeung CK, Herrmann A, Diefenbach S, Haan C, Küster A, Wortmann SB, Roderburg C, Heinrich PC, Behrmann I, Müller-Newen G
The Journal of biological chemistry 2003 Oct 3;278(40):39205-13
The Journal of biological chemistry 2003 Oct 3;278(40):39205-13
A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor.
Timmermann A, Küster A, Kurth I, Heinrich PC, Müller-Newen G
European journal of biochemistry 2002 Jun;269(11):2716-26
European journal of biochemistry 2002 Jun;269(11):2716-26
Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus.
Aoki Y, Narazaki M, Kishimoto T, Tosato G
Blood 2001 Nov 15;98(10):3042-9
Blood 2001 Nov 15;98(10):3042-9
Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130.
Kurth I, Horsten U, Pflanz S, Timmermann A, Küster A, Dahmen H, Tacken I, Heinrich PC, Müller-Newen G
Journal of immunology (Baltimore, Md. : 1950) 2000 Jan 1;164(1):273-82
Journal of immunology (Baltimore, Md. : 1950) 2000 Jan 1;164(1):273-82
Identification of a gp130 cytokine receptor critical site involved in oncostatin M response.
Olivier C, Auguste P, Chabbert M, Lelièvre E, Chevalier S, Gascan H
The Journal of biological chemistry 2000 Feb 25;275(8):5648-56
The Journal of biological chemistry 2000 Feb 25;275(8):5648-56
A gp130 interleukin-6 transducer-dependent SCID model of human multiple myeloma.
Rebouissou C, Wijdenes J, Autissier P, Tarte K, Costes V, Liautard J, Rossi JF, Brochier J, Klein B
Blood 1998 Jun 15;91(12):4727-37
Blood 1998 Jun 15;91(12):4727-37
Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex.
Horsten U, Müller-Newen G, Gerhartz C, Wollmer A, Wijdenes J, Heinrich PC, Grötzinger J
The Journal of biological chemistry 1997 Sep 19;272(38):23748-57
The Journal of biological chemistry 1997 Sep 19;272(38):23748-57
Interleukin-6: structure-function relationships.
Simpson RJ, Hammacher A, Smith DK, Matthews JM, Ward LD
Protein science : a publication of the Protein Society 1997 May;6(5):929-55
Protein science : a publication of the Protein Society 1997 May;6(5):929-55
Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties.
Lebeau B, Montero Julian FA, Wijdenes J, Müller-Newen G, Dahmen H, Chérel M, Heinrich PC, Brailly H, Hallet MM, Godard A, Minvielle S, Jacques Y
FEBS letters 1997 Apr 28;407(2):141-7
FEBS letters 1997 Apr 28;407(2):141-7
Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M.
Gu ZJ, Wijdenes J, Zhang XG, Hallet MM, Clement C, Klein B
Journal of immunological methods 1996 Mar 28;190(1):21-7
Journal of immunological methods 1996 Mar 28;190(1):21-7
Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein.
Chevalier S, Fourcin M, Robledo O, Wijdenes J, Pouplard-Barthelaix A, Gascan H
The Journal of biological chemistry 1996 Jun 21;271(25):14764-72
The Journal of biological chemistry 1996 Jun 21;271(25):14764-72
Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies.
Wijdenes J, Heinrich PC, Müller-Newen G, Roche C, Gu ZJ, Clément C, Klein B
European journal of immunology 1995 Dec;25(12):3474-81
European journal of immunology 1995 Dec;25(12):3474-81
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