Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- ABIN1105850 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) antibody
- Antibody type
- Monoclonal
- Description
- Ion Exchange Chromatography
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- B-R3
- Vial size
- 0.2 mg
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references Akt signaling pathway: a target for radiosensitizing human malignant glioma.
N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130.
In vivo modulation of soluble "antagonistic" IL-6 receptor synthesis and release in ESRD.
Soluble mannose 6-phosphate/insulin-like growth factor II (IGF-II) receptor inhibits interleukin-6-type cytokine-dependent proliferation by neutralization of IGF-II.
Down-regulation of human CYP3A4 by the inflammatory signal interleukin-6: molecular mechanism and transcription factors involved.
Nitrosative stress by cyclosporin A in the endothelium: studies with the NO-sensitive probe diaminofluorescein-2/diacetate using flow cytometry.
Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus.
Identification of agonistic and antagonistic antibodies against gp190, the leukemia inhibitory factor receptor, reveals distinct roles for its two cytokine-binding domains.
Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors.
Identification of a gp130 cytokine receptor critical site involved in oncostatin M response.
kappa-Conotoxin PVIIA is a peptide inhibiting the shaker K+ channel.
Signaling of type II oncostatin M receptor.
Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties.
Interleukin-10 is a growth factor for human myeloma cells by induction of an oncostatin M autocrine loop.
Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M.
Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein.
Chautard E, Loubeau G, Tchirkov A, Chassagne J, Vermot-Desroches C, Morel L, Verrelle P
Neuro-oncology 2010 May;12(5):434-43
Neuro-oncology 2010 May;12(5):434-43
N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130.
Waetzig GH, Chalaris A, Rosenstiel P, Suthaus J, Holland C, Karl N, Vallés Uriarte L, Till A, Scheller J, Grötzinger J, Schreiber S, Rose-John S, Seegert D
The Journal of biological chemistry 2010 Jan 15;285(3):1781-9
The Journal of biological chemistry 2010 Jan 15;285(3):1781-9
In vivo modulation of soluble "antagonistic" IL-6 receptor synthesis and release in ESRD.
Memoli B, Grandaliano G, Soccio M, Postiglione L, Guida B, Bisesti V, Esposito P, Procino A, Marrone D, Michael A, Andreucci M, Schena FP, Pertosa G
Journal of the American Society of Nephrology : JASN 2005 Apr;16(4):1099-107
Journal of the American Society of Nephrology : JASN 2005 Apr;16(4):1099-107
Soluble mannose 6-phosphate/insulin-like growth factor II (IGF-II) receptor inhibits interleukin-6-type cytokine-dependent proliferation by neutralization of IGF-II.
Duplomb L, Chaigne-Delalande B, Vusio P, Raher S, Jacques Y, Godard A, Blanchard F
Endocrinology 2003 Dec;144(12):5381-9
Endocrinology 2003 Dec;144(12):5381-9
Down-regulation of human CYP3A4 by the inflammatory signal interleukin-6: molecular mechanism and transcription factors involved.
Jover R, Bort R, Gómez-Lechón MJ, Castell JV
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002 Nov;16(13):1799-801
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002 Nov;16(13):1799-801
Nitrosative stress by cyclosporin A in the endothelium: studies with the NO-sensitive probe diaminofluorescein-2/diacetate using flow cytometry.
Navarro-Antolin J, Lamas S
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16 Suppl 1:6-9
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16 Suppl 1:6-9
Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus.
Aoki Y, Narazaki M, Kishimoto T, Tosato G
Blood 2001 Nov 15;98(10):3042-9
Blood 2001 Nov 15;98(10):3042-9
Identification of agonistic and antagonistic antibodies against gp190, the leukemia inhibitory factor receptor, reveals distinct roles for its two cytokine-binding domains.
Taupin JL, Legembre P, Bitard J, Daburon S, Pitard V, Blanchard F, Duplomb L, Godard A, Jacques Y, Moreau JF
The Journal of biological chemistry 2001 Dec 21;276(51):47975-81
The Journal of biological chemistry 2001 Dec 21;276(51):47975-81
Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors.
Gu ZJ, De Vos J, Rebouissou C, Jourdan M, Zhang XG, Rossi JF, Wijdenes J, Klein B
Leukemia 2000 Jan;14(1):188-97
Leukemia 2000 Jan;14(1):188-97
Identification of a gp130 cytokine receptor critical site involved in oncostatin M response.
Olivier C, Auguste P, Chabbert M, Lelièvre E, Chevalier S, Gascan H
The Journal of biological chemistry 2000 Feb 25;275(8):5648-56
The Journal of biological chemistry 2000 Feb 25;275(8):5648-56
kappa-Conotoxin PVIIA is a peptide inhibiting the shaker K+ channel.
Shon KJ, Stocker M, Terlau H, Stühmer W, Jacobsen R, Walker C, Grilley M, Watkins M, Hillyard DR, Gray WR, Olivera BM
The Journal of biological chemistry 1998 Jan 2;273(1):33-8
The Journal of biological chemistry 1998 Jan 2;273(1):33-8
Signaling of type II oncostatin M receptor.
Auguste P, Guillet C, Fourcin M, Olivier C, Veziers J, Pouplard-Barthelaix A, Gascan H
The Journal of biological chemistry 1997 Jun 20;272(25):15760-4
The Journal of biological chemistry 1997 Jun 20;272(25):15760-4
Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties.
Lebeau B, Montero Julian FA, Wijdenes J, Müller-Newen G, Dahmen H, Chérel M, Heinrich PC, Brailly H, Hallet MM, Godard A, Minvielle S, Jacques Y
FEBS letters 1997 Apr 28;407(2):141-7
FEBS letters 1997 Apr 28;407(2):141-7
Interleukin-10 is a growth factor for human myeloma cells by induction of an oncostatin M autocrine loop.
Gu ZJ, Costes V, Lu ZY, Zhang XG, Pitard V, Moreau JF, Bataille R, Wijdenes J, Rossi JF, Klein B
Blood 1996 Nov 15;88(10):3972-86
Blood 1996 Nov 15;88(10):3972-86
Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M.
Gu ZJ, Wijdenes J, Zhang XG, Hallet MM, Clement C, Klein B
Journal of immunological methods 1996 Mar 28;190(1):21-7
Journal of immunological methods 1996 Mar 28;190(1):21-7
Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein.
Chevalier S, Fourcin M, Robledo O, Wijdenes J, Pouplard-Barthelaix A, Gascan H
The Journal of biological chemistry 1996 Jun 21;271(25):14764-72
The Journal of biological chemistry 1996 Jun 21;271(25):14764-72
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