Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1383682 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human
- Isotype
- IgG
- Antibody clone number
- B-P8
- Vial size
- 200 µl
- Concentration
- 200µg/200µl
- Storage
- 2-8°C
Submitted references Dimerization of the cytokine receptors gp130 and LIFR analysed in single cells.
Long term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis.
A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor.
Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus.
Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors.
Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130.
Identification of a gp130 cytokine receptor critical site involved in oncostatin M response.
Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies.
A gp130 interleukin-6 transducer-dependent SCID model of human multiple myeloma.
Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex.
Interleukin-6: structure-function relationships.
Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties.
Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M.
Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein.
Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies.
Giese B, Roderburg C, Sommerauer M, Wortmann SB, Metz S, Heinrich PC, Müller-Newen G
Journal of cell science 2005 Nov 1;118(Pt 21):5129-40
Journal of cell science 2005 Nov 1;118(Pt 21):5129-40
Long term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis.
Giese B, Au-Yeung CK, Herrmann A, Diefenbach S, Haan C, Küster A, Wortmann SB, Roderburg C, Heinrich PC, Behrmann I, Müller-Newen G
The Journal of biological chemistry 2003 Oct 3;278(40):39205-13
The Journal of biological chemistry 2003 Oct 3;278(40):39205-13
A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor.
Timmermann A, Küster A, Kurth I, Heinrich PC, Müller-Newen G
European journal of biochemistry / FEBS 2002 Jun;269(11):2716-26
European journal of biochemistry / FEBS 2002 Jun;269(11):2716-26
Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus.
Aoki Y, Narazaki M, Kishimoto T, Tosato G
Blood 2001 Nov 15;98(10):3042-9
Blood 2001 Nov 15;98(10):3042-9
Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors.
Gu ZJ, De Vos J, Rebouissou C, Jourdan M, Zhang XG, Rossi JF, Wijdenes J, Klein B
Leukemia 2000 Jan;14(1):188-97
Leukemia 2000 Jan;14(1):188-97
Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130.
Kurth I, Horsten U, Pflanz S, Timmermann A, Küster A, Dahmen H, Tacken I, Heinrich PC, Müller-Newen G
Journal of immunology (Baltimore, Md. : 1950) 2000 Jan 1;164(1):273-82
Journal of immunology (Baltimore, Md. : 1950) 2000 Jan 1;164(1):273-82
Identification of a gp130 cytokine receptor critical site involved in oncostatin M response.
Olivier C, Auguste P, Chabbert M, Lelièvre E, Chevalier S, Gascan H
The Journal of biological chemistry 2000 Feb 25;275(8):5648-56
The Journal of biological chemistry 2000 Feb 25;275(8):5648-56
Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies.
Müller-Newen G, Küster A, Wijdenes J, Schaper F, Heinrich PC
The Journal of biological chemistry 2000 Feb 18;275(7):4579-86
The Journal of biological chemistry 2000 Feb 18;275(7):4579-86
A gp130 interleukin-6 transducer-dependent SCID model of human multiple myeloma.
Rebouissou C, Wijdenes J, Autissier P, Tarte K, Costes V, Liautard J, Rossi JF, Brochier J, Klein B
Blood 1998 Jun 15;91(12):4727-37
Blood 1998 Jun 15;91(12):4727-37
Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex.
Horsten U, Müller-Newen G, Gerhartz C, Wollmer A, Wijdenes J, Heinrich PC, Grötzinger J
The Journal of biological chemistry 1997 Sep 19;272(38):23748-57
The Journal of biological chemistry 1997 Sep 19;272(38):23748-57
Interleukin-6: structure-function relationships.
Simpson RJ, Hammacher A, Smith DK, Matthews JM, Ward LD
Protein science : a publication of the Protein Society 1997 May;6(5):929-55
Protein science : a publication of the Protein Society 1997 May;6(5):929-55
Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties.
Lebeau B, Montero Julian FA, Wijdenes J, Müller-Newen G, Dahmen H, Chérel M, Heinrich PC, Brailly H, Hallet MM, Godard A, Minvielle S, Jacques Y
FEBS letters 1997 Apr 28;407(2):141-7
FEBS letters 1997 Apr 28;407(2):141-7
Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M.
Gu ZJ, Wijdenes J, Zhang XG, Hallet MM, Clement C, Klein B
Journal of immunological methods 1996 Mar 28;190(1):21-7
Journal of immunological methods 1996 Mar 28;190(1):21-7
Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein.
Chevalier S, Fourcin M, Robledo O, Wijdenes J, Pouplard-Barthelaix A, Gascan H
The Journal of biological chemistry 1996 Jun 21;271(25):14764-72
The Journal of biological chemistry 1996 Jun 21;271(25):14764-72
Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies.
Wijdenes J, Heinrich PC, Müller-Newen G, Roche C, Gu ZJ, Clément C, Klein B
European journal of immunology 1995 Dec;25(12):3474-81
European journal of immunology 1995 Dec;25(12):3474-81
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