Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 17918-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17918-1-AP, RRID:AB_2192708
- Product name
- SNX5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SNX5 antibody (Cat. #17918-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Super-enhancer-driven Sorting Nexin 5 expression promotes dopaminergic neuronal ferroptosis in Parkinson's disease models.
Sorting nexin 1 loss results in increased oxidative stress and hypertension.
A heterodimeric SNX4--SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly.
Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.
Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.
Si W, Huang Z, Li X, Zhao L, Ji Y, Li H, Liu X, Ye S, Chen D, Liu H, Kuang W, Zhu M
Biochemical and biophysical research communications 2021 Aug 27;567:35-41
Biochemical and biophysical research communications 2021 Aug 27;567:35-41
Sorting nexin 1 loss results in increased oxidative stress and hypertension.
Yang J, Asico LD, Beitelshees AL, Feranil JB, Wang X, Jones JE, Armando I, Cuevas SG, Schwartz GL, Gums JG, Chapman AB, Turner ST, Boerwinkle E, Cooper-DeHoff RM, Johnson JA, Felder RA, Weinman EJ, Zeng C, Jose PA, Villar VAM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7941-7957
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7941-7957
A heterodimeric SNX4--SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly.
Antón Z, Betin VMS, Simonetti B, Traer CJ, Attar N, Cullen PJ, Lane JD
Journal of cell science 2020 Jul 15;133(14)
Journal of cell science 2020 Jul 15;133(14)
Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Simonetti B, Paul B, Chaudhari K, Weeratunga S, Steinberg F, Gorla M, Heesom KJ, Bashaw GJ, Collins BM, Cullen PJ
Nature cell biology 2019 Oct;21(10):1219-1233
Nature cell biology 2019 Oct;21(10):1219-1233
SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.
McGough IJ, de Groot REA, Jellett AP, Betist MC, Varandas KC, Danson CM, Heesom KJ, Korswagen HC, Cullen PJ
Nature communications 2018 Sep 13;9(1):3737
Nature communications 2018 Sep 13;9(1):3737
Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.
Simonetti B, Danson CM, Heesom KJ, Cullen PJ
The Journal of cell biology 2017 Nov 6;216(11):3695-3712
The Journal of cell biology 2017 Nov 6;216(11):3695-3712
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 17918-1-AP(SNX5 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17918-1-AP(SNX5 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SNX5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SNX5. This antibody recognizes human, mouse, rat antigen. The SNX5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.