Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 17918-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17918-1-AP, RRID:AB_2192708
- Product name
- SNX5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SNX5 antibody (Cat. #17918-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Chlamydia effector IncE employs two short linear motifs to reprogram host vesicle trafficking.
Hsa_circRNA_0084043 promoting tumorigenesis in glioma through miR-577 sponging.
Five Inhibitory Receptors Display Distinct Vesicular Distributions in Murine T Cells.
Five inhibitory receptors display distinct vesicular distributions in T cells.
Sorting Nexin 5 Plays an Important Role in Promoting Ferroptosis in Parkinson's Disease.
iTRAQ-based quantitative proteomic analysis of the liver regeneration termination phase after partial hepatectomy in mice.
Retromer dysfunction in amyotrophic lateral sclerosis.
Super-enhancer-driven Sorting Nexin 5 expression promotes dopaminergic neuronal ferroptosis in Parkinson's disease models.
Sorting nexin 1 loss results in increased oxidative stress and hypertension.
A heterodimeric SNX4--SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly.
Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.
Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.
Pha K, Mirrashidi K, Sherry J, Tran CJ, Herrera CM, McMahon E, Elwell CA, Engel JN
bioRxiv : the preprint server for biology 2024 Apr 24;
bioRxiv : the preprint server for biology 2024 Apr 24;
Hsa_circRNA_0084043 promoting tumorigenesis in glioma through miR-577 sponging.
Qian J, Chen C, Zhao C, Xu X, Xu Y, Zhang Y, Qian C
Heliyon 2023 Sep;9(9):e19219
Heliyon 2023 Sep;9(9):e19219
Five Inhibitory Receptors Display Distinct Vesicular Distributions in Murine T Cells.
Lu J, Veler A, Simonetti B, Raj T, Chou PH, Cross SJ, Phillips AM, Ruan X, Huynh L, Dowsey AW, Ye D, Murphy RF, Verkade P, Cullen PJ, Wülfing C
Cells 2023 Oct 31;12(21)
Cells 2023 Oct 31;12(21)
Five inhibitory receptors display distinct vesicular distributions in T cells.
Lu J, Veler A, Simonetti B, Raj T, Chou PH, Cross SJ, Phillips AM, Ruan X, Huynh L, Dowsey AW, Ye D, Murphy RF, Verkade P, Cullen PJ, Wülfing C
bioRxiv : the preprint server for biology 2023 Jul 25;
bioRxiv : the preprint server for biology 2023 Jul 25;
Sorting Nexin 5 Plays an Important Role in Promoting Ferroptosis in Parkinson's Disease.
Huang Z, Han J, Wu P, Wu C, Fan Y, Zhao L, Hao X, Chen D, Zhu M
Oxidative medicine and cellular longevity 2022;2022:5463134
Oxidative medicine and cellular longevity 2022;2022:5463134
iTRAQ-based quantitative proteomic analysis of the liver regeneration termination phase after partial hepatectomy in mice.
Wu J, Liu H, Wang H, Wang Y, Cheng Q, Zhao R, Gao H, Fang L, Zhu F, Xue B
Journal of proteomics 2022 Sep 15;267:104688
Journal of proteomics 2022 Sep 15;267:104688
Retromer dysfunction in amyotrophic lateral sclerosis.
Pérez-Torres EJ, Utkina-Sosunova I, Mishra V, Barbuti P, De Planell-Saguer M, Dermentzaki G, Geiger H, Basile AO, Robine N, Fagegaltier D, Politi KA, Rinchetti P, Jackson-Lewis V, NYGC ALS Consortium, Harms M, Phatnani H, Lotti F, Przedborski S
Proceedings of the National Academy of Sciences of the United States of America 2022 Jun 28;119(26):e2118755119
Proceedings of the National Academy of Sciences of the United States of America 2022 Jun 28;119(26):e2118755119
Super-enhancer-driven Sorting Nexin 5 expression promotes dopaminergic neuronal ferroptosis in Parkinson's disease models.
Si W, Huang Z, Li X, Zhao L, Ji Y, Li H, Liu X, Ye S, Chen D, Liu H, Kuang W, Zhu M
Biochemical and biophysical research communications 2021 Aug 27;567:35-41
Biochemical and biophysical research communications 2021 Aug 27;567:35-41
Sorting nexin 1 loss results in increased oxidative stress and hypertension.
Yang J, Asico LD, Beitelshees AL, Feranil JB, Wang X, Jones JE, Armando I, Cuevas SG, Schwartz GL, Gums JG, Chapman AB, Turner ST, Boerwinkle E, Cooper-DeHoff RM, Johnson JA, Felder RA, Weinman EJ, Zeng C, Jose PA, Villar VAM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7941-7957
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7941-7957
A heterodimeric SNX4--SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly.
Antón Z, Betin VMS, Simonetti B, Traer CJ, Attar N, Cullen PJ, Lane JD
Journal of cell science 2020 Jul 15;133(14)
Journal of cell science 2020 Jul 15;133(14)
Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Simonetti B, Paul B, Chaudhari K, Weeratunga S, Steinberg F, Gorla M, Heesom KJ, Bashaw GJ, Collins BM, Cullen PJ
Nature cell biology 2019 Oct;21(10):1219-1233
Nature cell biology 2019 Oct;21(10):1219-1233
SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.
McGough IJ, de Groot REA, Jellett AP, Betist MC, Varandas KC, Danson CM, Heesom KJ, Korswagen HC, Cullen PJ
Nature communications 2018 Sep 13;9(1):3737
Nature communications 2018 Sep 13;9(1):3737
Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.
Simonetti B, Danson CM, Heesom KJ, Cullen PJ
The Journal of cell biology 2017 Nov 6;216(11):3695-3712
The Journal of cell biology 2017 Nov 6;216(11):3695-3712
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 17918-1-AP(SNX5 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17918-1-AP(SNX5 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SNX5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SNX5. This antibody recognizes human, mouse, rat antigen. The SNX5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.