MAB23651

antibody from R&D Systems

Targeting: HAVCR2 CD366, FLJ14428, Tim-3, TIM3, TIMD3

No application information provided.

Antibody Data

Product number

MAB23651

Provider

R&D Systems

Product name

Human TIM-3 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects recombinant human TIM-3 in direct ELISAs and Western blots.

Reactivity

Human

Host

Rat

Conjugate

Unconjugated

Antigen sequence

Q8TDQ0


Isotype

IgG

Antibody clone number

344801

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Frontline Science: Tim-3-mediated dysfunctional engulfment of apoptotic cells in SLE.

Zhao D, Guo M, Liu B, Lin Q, Xie T, Zhang Q, Jia X, Shu Q, Liang X, Gao L, Ma C
Journal of leukocyte biology 2017 Dec;102(6):1313-1322

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Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9.

Schwartz JA, Clayton KL, Mujib S, Zhang H, Rahman AK, Liu J, Yue FY, Benko E, Kovacs C, Ostrowski MA
Journal of immunology (Baltimore, Md. : 1950) 2017 Apr 15;198(8):3181-3194

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Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.

Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK
PLoS pathogens 2016 Jun;12(6):e1005677