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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [18]
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- Product number
- 60355-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- TIM3 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated TIM3 antibody (Cat. #60355-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig, mouse, rat and has been validated for the following applications: FC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4C4G3
- Vial size
- 20ul, 150ul
Submitted references Expression levels of key immune indicators and immune checkpoints in manganese-exposed rats.
Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy.
Tim3scFv-Transforming Lactobacillus Inhibits Transplanted Tumor of Renal-Cell Carcinoma.
Effects of Nanosecond Pulsed Electric Field on Immune Checkpoint Receptors in Melanoma Cells.
Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes.
Comprehensive Analysis of HHLA2 as a Prognostic Biomarker and Its Association With Immune Infiltrates in Hepatocellular Carcinoma.
The immune checkpoint expression in the tumor immune microenvironment of DLBCL: Clinicopathologic features and prognosis.
Cancer cell intrinsic TIM-3 induces glioblastoma progression.
Aberrantly Expressed Galectin-9 Is Involved in the Immunopathogenesis of Anti-MDA5-Positive Dermatomyositis-Associated Interstitial Lung Disease.
Galectin-9/TIM-3 as a Key Regulator of Immune Response in Gliomas With Chromosome 1p/19q Codeletion.
Up-Regulation of Immune Checkpoints in the Thymus of PRRSV-1-Infected Piglets in a Virulence-Dependent Fashion.
Molecular subtyping reveals immune alterations in IDH wild-type lower-grade diffuse glioma.
Tim‑3 regulates the ability of macrophages to counter lipopolysaccharide‑induced pulmonary epithelial barrier dysfunction via the PI3K/Akt pathway in epithelial cells.
Cross-regulation by TLR4 and T cell Ig mucin-3 determines severity of liver injury in a CCl4-induced mouse model.
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway.
Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis.
Low TIM3 expression indicates poor prognosis of metastatic prostate cancer and acts as an independent predictor of castration resistant status.
Qi Y, Si H, Jin X, Guo Y, Xia J, He J, Deng X, Deng M, Yao W, Hao C
Ecotoxicology and environmental safety 2024 Mar 1;272:116029
Ecotoxicology and environmental safety 2024 Mar 1;272:116029
Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy.
Zhang Z, Xu X, Du J, Chen X, Xue Y, Zhang J, Yang X, Chen X, Xie J, Ju S
Nature communications 2024 Feb 6;15(1):1118
Nature communications 2024 Feb 6;15(1):1118
Tim3scFv-Transforming Lactobacillus Inhibits Transplanted Tumor of Renal-Cell Carcinoma.
Chen Z, Zhang H, Hui J, Jiang Y, Huang Z, Chen Z, Zeng W
Urologia internationalis 2023;107(2):202-213
Urologia internationalis 2023;107(2):202-213
Effects of Nanosecond Pulsed Electric Field on Immune Checkpoint Receptors in Melanoma Cells.
Sauer N, Szlasa W, Szewczyk A, Novickij V, Saczko J, Baczyńska D, Daczewska M, Kulbacka J
Pharmaceuticals (Basel, Switzerland) 2023 Sep 27;16(10)
Pharmaceuticals (Basel, Switzerland) 2023 Sep 27;16(10)
Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes.
Wu F, Yin YY, Fan WH, Zhai Y, Yu MC, Wang D, Pan CQ, Zhao Z, Li GZ, Zhang W
EBioMedicine 2023 Jan;87:104410
EBioMedicine 2023 Jan;87:104410
Comprehensive Analysis of HHLA2 as a Prognostic Biomarker and Its Association With Immune Infiltrates in Hepatocellular Carcinoma.
Ding L, Yu Q, Yang S, Yang WJ, Liu T, Xian JR, Tian TT, Li T, Chen W, Wang BL, Pan BS, Zhou J, Fan J, Yang XR, Guo W
Frontiers in immunology 2022;13:831101
Frontiers in immunology 2022;13:831101
The immune checkpoint expression in the tumor immune microenvironment of DLBCL: Clinicopathologic features and prognosis.
Ma J, Pang X, Li J, Zhang W, Cui W
Frontiers in oncology 2022;12:1069378
Frontiers in oncology 2022;12:1069378
Cancer cell intrinsic TIM-3 induces glioblastoma progression.
Guo Q, Shen S, Guan G, Zhu C, Zou C, Cao J, Cheng W, Xu X, Yu J, Lin Z, Wang G, Chen L, Cheng P, Wu A
iScience 2022 Nov 18;25(11):105329
iScience 2022 Nov 18;25(11):105329
Aberrantly Expressed Galectin-9 Is Involved in the Immunopathogenesis of Anti-MDA5-Positive Dermatomyositis-Associated Interstitial Lung Disease.
Liang L, Zhang YM, Shen YW, Song AP, Li WL, Ye LF, Lu X, Wang GC, Peng QL
Frontiers in cell and developmental biology 2021;9:628128
Frontiers in cell and developmental biology 2021;9:628128
Galectin-9/TIM-3 as a Key Regulator of Immune Response in Gliomas With Chromosome 1p/19q Codeletion.
Li G, Huang R, Fan W, Wang D, Wu F, Zeng F, Yu M, Zhai Y, Chang Y, Pan C, Jiang T, Yan W, Wang H, Zhang W
Frontiers in immunology 2021;12:800928
Frontiers in immunology 2021;12:800928
Up-Regulation of Immune Checkpoints in the Thymus of PRRSV-1-Infected Piglets in a Virulence-Dependent Fashion.
Ruedas-Torres I, Rodríguez-Gómez IM, Sánchez-Carvajal JM, Guil-Luna S, Larenas-Muñoz F, Pallarés FJ, Carrasco L, Gómez-Laguna J
Frontiers in immunology 2021;12:671743
Frontiers in immunology 2021;12:671743
Molecular subtyping reveals immune alterations in IDH wild-type lower-grade diffuse glioma.
Wu F, Li GZ, Liu HJ, Zhao Z, Chai RC, Liu YQ, Jiang HY, Zhai Y, Feng YM, Li RP, Zhang W
The Journal of pathology 2020 Jul;251(3):272-283
The Journal of pathology 2020 Jul;251(3):272-283
Tim‑3 regulates the ability of macrophages to counter lipopolysaccharide‑induced pulmonary epithelial barrier dysfunction via the PI3K/Akt pathway in epithelial cells.
Zhang Y, Zhang W
Molecular medicine reports 2020 Jul;22(1):534-542
Molecular medicine reports 2020 Jul;22(1):534-542
Cross-regulation by TLR4 and T cell Ig mucin-3 determines severity of liver injury in a CCl4-induced mouse model.
Zhao L, Liang J, Rao W, Cui M, Ren S, Zhang L, Xu D, Han Q, Zang YJ, Zhang B
Scandinavian journal of immunology 2020 Apr;91(4):e12851
Scandinavian journal of immunology 2020 Apr;91(4):e12851
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Zhang D, Ren L, Zhao M, Yang C, Liu X, Zhang H, Jiang Y, Sun X, Li T, Cui L, Hu X
Frontiers in immunology 2019;10:1550
Frontiers in immunology 2019;10:1550
Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway.
Yang H, Xie T, Li D, Du X, Wang T, Li C, Song X, Xu L, Yi F, Liang X, Gao L, Yang X, Ma C
Molecular metabolism 2019 May;23:24-36
Molecular metabolism 2019 May;23:24-36
Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis.
Zhang H, Song Y, Yang H, Liu Z, Gao L, Liang X, Ma C
Oncogene 2018 May;37(18):2456-2468
Oncogene 2018 May;37(18):2456-2468
Low TIM3 expression indicates poor prognosis of metastatic prostate cancer and acts as an independent predictor of castration resistant status.
Wu J, Lin G, Zhu Y, Zhang H, Shi G, Shen Y, Zhu Y, Dai B, Ye D
Scientific reports 2017 Aug 21;7(1):8869
Scientific reports 2017 Aug 21;7(1):8869
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