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- References [13]
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- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 13384-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13384-1-AP, RRID:AB_2056499
- Product name
- AP3B1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AP3B1 antibody (Cat. #13384-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.
Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.
In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids.
Modeling of Fibrotic Lung Disease Using 3D Organoids Derived from Human Pluripotent Stem Cells.
Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear.
Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5.
Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model.
Matrix proteins of Nipah and Hendra viruses interact with beta subunits of AP-3 complexes.
The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα.
Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis.
Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1.
BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles.
Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells.
Kannangara AR, Poole DM, McEwan CM, Youngs JC, Weerasekara VK, Thornock AM, Lazaro MT, Balasooriya ER, Oh LM, Soderblom EJ, Lee JJ, Simmons DL, Andersen JL
EMBO reports 2021 Oct 5;22(10):e51136
EMBO reports 2021 Oct 5;22(10):e51136
Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.
Karampini E, Schillemans M, Hofman M, van Alphen F, de Boer M, Kuijpers TW, van den Biggelaar M, Voorberg J, Bierings R
Haematologica 2019 Oct;104(10):2091-2099
Haematologica 2019 Oct;104(10):2091-2099
In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids.
Korogi Y, Gotoh S, Ikeo S, Yamamoto Y, Sone N, Tamai K, Konishi S, Nagasaki T, Matsumoto H, Ito I, Chen-Yoshikawa TF, Date H, Hagiwara M, Asaka I, Hotta A, Mishima M, Hirai T
Stem cell reports 2019 Mar 5;12(3):431-440
Stem cell reports 2019 Mar 5;12(3):431-440
Modeling of Fibrotic Lung Disease Using 3D Organoids Derived from Human Pluripotent Stem Cells.
Strikoudis A, Cieślak A, Loffredo L, Chen YW, Patel N, Saqi A, Lederer DJ, Snoeck HW
Cell reports 2019 Jun 18;27(12):3709-3723.e5
Cell reports 2019 Jun 18;27(12):3709-3723.e5
Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear.
Tower-Gilchrist C, Zlatic SA, Yu D, Chang Q, Wu H, Lin X, Faundez V, Chen P
Molecular biology of the cell 2019 Aug 15;30(18):2422-2434
Molecular biology of the cell 2019 Aug 15;30(18):2422-2434
Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5.
Stephen J, Yokoyama T, Tolman NJ, O'Brien KJ, Nicoli ER, Brooks BP, Huryn L, Titus SA, Adams DR, Chen D, Gahl WA, Gochuico BR, Malicdan MC
PloS one 2017;12(3):e0173682
PloS one 2017;12(3):e0173682
Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model.
Bagh MB, Peng S, Chandra G, Zhang Z, Singh SP, Pattabiraman N, Liu A, Mukherjee AB
Nature communications 2017 Mar 7;8:14612
Nature communications 2017 Mar 7;8:14612
Matrix proteins of Nipah and Hendra viruses interact with beta subunits of AP-3 complexes.
Sun W, McCrory TS, Khaw WY, Petzing S, Myers T, Schmitt AP
Journal of virology 2014 Nov;88(22):13099-110
Journal of virology 2014 Nov;88(22):13099-110
The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα.
Ryder PV, Vistein R, Gokhale A, Seaman MN, Puthenveedu MA, Faundez V
Molecular biology of the cell 2013 Jul;24(14):2269-84
Molecular biology of the cell 2013 Jul;24(14):2269-84
Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis.
Zlatic SA, Grossniklaus EJ, Ryder PV, Salazar G, Mattheyses AL, Peden AA, Faundez V
Molecular biology of the cell 2013 Aug;24(15):2378-88
Molecular biology of the cell 2013 Aug;24(15):2378-88
Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1.
Gokhale A, Larimore J, Werner E, So L, Moreno-De-Luca A, Lese-Martin C, Lupashin VV, Smith Y, Faundez V
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Mar 14;32(11):3697-711
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Mar 14;32(11):3697-711
BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles.
Bultema JJ, Ambrosio AL, Burek CL, Di Pietro SM
The Journal of biological chemistry 2012 Jun 1;287(23):19550-63
The Journal of biological chemistry 2012 Jun 1;287(23):19550-63
Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells.
Zlatic SA, Tornieri K, L'Hernault SW, Faundez V
Molecular biology of the cell 2011 May 15;22(10):1699-715
Molecular biology of the cell 2011 May 15;22(10):1699-715
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse thymus tissue were subjected to SDS PAGE followed by western blot with 13384-1-AP(AP3B1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AP3B1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AP3B1. This antibody recognizes human,mouse,rat antigen. The AP3B1 antibody has been validated for the following applications: ELISA, WB, IP analysis.
