Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations [0]
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- Product number
- 10708-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SAT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SAT1 antibody (Cat. #10708-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model.
Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway.
Polyamine Catabolism and Its Role in Renal Injury and Fibrosis in Mice Subjected to Repeated Low-Dose Cisplatin Treatment.
Electroacupuncture Alleviates Neuropathic Pain by Suppressing Ferroptosis in Dorsal Root Ganglion via SAT1/ALOX15 Signaling.
Acidic extracellular pH drives accumulation of N1-acetylspermidine and recruitment of protumor neutrophils.
The oncogenic properties of the EWSR1::CREM fusion gene are associated with polyamine metabolism.
A role of GABA(A) receptor α1 subunit in the hippocampus for rapid-acting antidepressant-like effects of ketamine.
Inhibition of YAP by lenvatinib in endothelial cells increases blood pressure through ferroptosis.
Urea cycle activation triggered by host-microbiota maladaptation driving colorectal tumorigenesis.
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Activation of SSAT1/ALOX15 Axis Aggravates Cerebral Ischemia/Reperfusion Injury via Triggering Neuronal Ferroptosis.
DEHP induces ferroptosis in testes via p38α-lipid ROS circulation and destroys the BTB integrity.
Exogenous spermidine affects polyamine metabolism in the mouse hypothalamus.
ASMTL-AS1 impedes the malignant progression of lung adenocarcinoma by regulating SAT1 to promote ferroptosis.
Knockdown of SSATX, an alternative splicing variant of the SAT1 gene, promotes melanoma progression.
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.
Polyamine pathway contributes to the pathogenesis of Parkinson disease.
Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.
Feng L, Wang C, Zhang C, Zhang W, Zhu W, He Y, Xia Z, Song W
Neural regeneration research 2024 Oct 1;19(10):2299-2309
Neural regeneration research 2024 Oct 1;19(10):2299-2309
Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway.
Xu J, Ruan Z, Guo Z, Hou L, Wang G, Zheng Z, Zhang X, Liu H, Sun K, Guo F
Bone & joint research 2024 Mar 7;13(3):110-123
Bone & joint research 2024 Mar 7;13(3):110-123
Polyamine Catabolism and Its Role in Renal Injury and Fibrosis in Mice Subjected to Repeated Low-Dose Cisplatin Treatment.
Zahedi K, Barone S, Brooks M, Stewart TM, Foley JR, Nwafor A, Casero RA Jr, Soleimani M
Biomedicines 2024 Mar 13;12(3)
Biomedicines 2024 Mar 13;12(3)
Electroacupuncture Alleviates Neuropathic Pain by Suppressing Ferroptosis in Dorsal Root Ganglion via SAT1/ALOX15 Signaling.
Wan K, Jia M, Zhang H, Lan Y, Wang S, Zhang K, Wang Z, Zhu H, Zheng X, Luo Y, Pei L, Wu C, Liu Y, Li M
Molecular neurobiology 2023 Oct;60(10):6121-6132
Molecular neurobiology 2023 Oct;60(10):6121-6132
Acidic extracellular pH drives accumulation of N1-acetylspermidine and recruitment of protumor neutrophils.
Kato M, Maeda K, Nakahara R, Hirose H, Kondo A, Aki S, Sugaya M, Hibino S, Nishida M, Hasegawa M, Morita H, Ando R, Tsuchida R, Yoshida M, Kodama T, Yanai H, Shimamura T, Osawa T
PNAS nexus 2023 Oct;2(10):pgad306
PNAS nexus 2023 Oct;2(10):pgad306
The oncogenic properties of the EWSR1::CREM fusion gene are associated with polyamine metabolism.
Kaprio H, Siddiqui A, Saustila L, Heuser VD, Gardberg M
Scientific reports 2023 Mar 25;13(1):4884
Scientific reports 2023 Mar 25;13(1):4884
A role of GABA(A) receptor α1 subunit in the hippocampus for rapid-acting antidepressant-like effects of ketamine.
Tang XH, Diao YG, Ren ZY, Zang YY, Zhang GF, Wang XM, Duan GF, Shen JC, Hashimoto K, Zhou ZQ, Yang JJ
Neuropharmacology 2023 Mar 1;225:109383
Neuropharmacology 2023 Mar 1;225:109383
Inhibition of YAP by lenvatinib in endothelial cells increases blood pressure through ferroptosis.
Liang C, Zhu D, Xia W, Hong Z, Wang QS, Sun Y, Yang YC, Han SQ, Tang LL, Lou J, Wu MM, Zhang ZR
Biochimica et biophysica acta. Molecular basis of disease 2023 Jan 1;1869(1):166586
Biochimica et biophysica acta. Molecular basis of disease 2023 Jan 1;1869(1):166586
Urea cycle activation triggered by host-microbiota maladaptation driving colorectal tumorigenesis.
Chen H, Tong T, Lu SY, Ji L, Xuan B, Zhao G, Yan Y, Song L, Zhao L, Xie Y, Leng X, Zhang X, Cui Y, Chen X, Xiong H, Yu T, Li X, Sun T, Wang Z, Chen J, Chen YX, Hong J, Fang JY
Cell metabolism 2023 Apr 4;35(4):651-666.e7
Cell metabolism 2023 Apr 4;35(4):651-666.e7
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Dang Y, He Q, Yang S, Sun H, Liu Y, Li W, Tang Y, Zheng Y, Wu T
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.
Li J, Sun Y, Yan R, Wu X, Zou H, Meng Y
Biochimica et biophysica acta. Molecular cell research 2022 May;1869(5):119236
Biochimica et biophysica acta. Molecular cell research 2022 May;1869(5):119236
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Halloran KM, Stenhouse C, Moses RM, Seo H, Johnson GA, Wu G, Bazer FW
Biology of reproduction 2022 May 17;106(5):865-878
Biology of reproduction 2022 May 17;106(5):865-878
Activation of SSAT1/ALOX15 Axis Aggravates Cerebral Ischemia/Reperfusion Injury via Triggering Neuronal Ferroptosis.
Zhao J, Wu Y, Liang S, Piao X
Neuroscience 2022 Mar 1;485:78-90
Neuroscience 2022 Mar 1;485:78-90
DEHP induces ferroptosis in testes via p38α-lipid ROS circulation and destroys the BTB integrity.
Yang L, Jiang L, Sun X, Li J, Wang N, Liu X, Yao X, Zhang C, Deng H, Wang S, Yang G
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113046
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113046
Exogenous spermidine affects polyamine metabolism in the mouse hypothalamus.
Jiang D, Mo G, Jiang Y, Kang B
Open life sciences 2021;16(1):39-45
Open life sciences 2021;16(1):39-45
ASMTL-AS1 impedes the malignant progression of lung adenocarcinoma by regulating SAT1 to promote ferroptosis.
Sui X, Hu N, Zhang Z, Wang Y, Wang P, Xiu G
Pathology international 2021 Nov;71(11):741-751
Pathology international 2021 Nov;71(11):741-751
Knockdown of SSATX, an alternative splicing variant of the SAT1 gene, promotes melanoma progression.
Yang Q, Deng Y, Xu Y, Ding N, Wang C, Zhao X, Lou X, Li Y, Zhao H, Fang X
Gene 2019 Oct 20;716:144010
Gene 2019 Oct 20;716:144010
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Wu YY, Li TM, Zang LQ, Liu B, Wang GX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.
Yin K, Lei Y, Wen X, Lacruz RS, Soleimani M, Kurtz I, Snead ML, White SN, Paine ML
PloS one 2015;10(12):e0144703
PloS one 2015;10(12):e0144703
Polyamine pathway contributes to the pathogenesis of Parkinson disease.
Lewandowski NM, Ju S, Verbitsky M, Ross B, Geddie ML, Rockenstein E, Adame A, Muhammad A, Vonsattel JP, Ringe D, Cote L, Lindquist S, Masliah E, Petsko GA, Marder K, Clark LN, Small SA
Proceedings of the National Academy of Sciences of the United States of America 2010 Sep 28;107(39):16970-5
Proceedings of the National Academy of Sciences of the United States of America 2010 Sep 28;107(39):16970-5
Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.
Guo Y, Zhang X, Huang J, Zeng Y, Liu W, Geng C, Li KW, Yang D, Wu S, Wei H, Han Z, Qian X, Jiang Y, He F
PloS one 2009 Oct 28;4(10):e7641
PloS one 2009 Oct 28;4(10):e7641
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