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- References [26]
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- Product number
- 13463-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13463-1-AP, RRID:AB_2161536
- Product name
- PER1 antibody
- Antibody type
- Polyclonal
- Description
- PER1 antibody (Cat. #13463-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Circadian Clock Dysfunction Exacerbate Autistic-Like Behaviour and Wnt/β-Catenin Signalling Dysregulation in ASD Mice and Treatment of Melatonin.
The crosstalk between CREB and PER2 mediates the transition between mania- and depression-like behavior.
Discovery, asymmetric synthesis and biological evaluation of new bisbenzylisoquinoline-orexin receptor antagonists for insomnia treatment.
Neuro-skeletal crosstalk: Brain-derived 5-HT mediates the bone-protective effects of β-Sitosterol against postmenopausal osteoporosis.
Loss of ARNTL Enhances ER Stress and Apoptosis in CKD Through Disruption of NRF2 Signaling.
Study on the Mechanisms of Ischemic Stroke Impacting Sleep Homeostasis and Circadian Rhythms in Rats.
Vitamin B12 Protects Against Early Diabetic Kidney Injury and Alters Clock Gene Expression in Mice.
Inhibition of Circadian Rhythm Gene per1 Promotes Macrophage Infiltration in e‑Cigarette Aerosol-Induced Pulmonary Fibrosis in Mice.
Sulforaphane Improves Liver Metabolism and Gut Microbiota in Circadian Rhythm Disorder Mice Models Fed With High-Fat Diets.
Rhythm gene PER1 mediates ferroptosis and lipid metabolism through SREBF2/ALOX15 axis in polycystic ovary syndrome.
Dysfunctional circadian clock accelerates cancer metastasis by intestinal microbiota triggering accumulation of myeloid-derived suppressor cells.
Disruption of local circadian clocks in aristolochic acid-induced nephropathy in mice.
Uncovering the Novel Role of NR1D1 in Regulating BNIP3-Mediated Mitophagy in Ulcerative Colitis.
Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization.
In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA.
Prognostic risk factors of serous ovarian carcinoma based on mesenchymal stem cell phenotype and guidance for therapeutic efficacy.
Sleep Fragmentation, Electroencephalographic Slowing, and Circadian Disarray in a Mouse Model for Intensive Care Unit Delirium.
PER1 promotes functional recovery of mice with hindlimb ischemia by inducing anti-inflammatory macrophage polarization.
CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice.
Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model.
The association between disruption of the circadian rhythm and aggravation of colitis in mice.
Capsaicin Attenuates Oleic Acid-Induced Lipid Accumulation via the Regulation of Circadian Clock Genes in HepG2 Cells.
PER1 as a Tumor Suppressor Attenuated in the Malignant Phenotypes of Breast Cancer Cells.
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice.
Loss of circadian protein TIMELESS accelerates the progression of cellular senescence.
Zhang Y, Chen Y, Li W, Tang L, Wang G, Li J, Feng X
Journal of cellular and molecular medicine 2026 Jan;30(1):e70991
Journal of cellular and molecular medicine 2026 Jan;30(1):e70991
The crosstalk between CREB and PER2 mediates the transition between mania- and depression-like behavior.
Wang XL, Ji YB, Li SX, Serchov T
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2025 Oct;50(11):1683-1694
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2025 Oct;50(11):1683-1694
Discovery, asymmetric synthesis and biological evaluation of new bisbenzylisoquinoline-orexin receptor antagonists for insomnia treatment.
Fang J, Wang Y, He J, Ge C, Zhang Y, Liu Y, Jiang Y, Liu S
European journal of medicinal chemistry 2025 Nov 5;297:117957
European journal of medicinal chemistry 2025 Nov 5;297:117957
Neuro-skeletal crosstalk: Brain-derived 5-HT mediates the bone-protective effects of β-Sitosterol against postmenopausal osteoporosis.
Wang K, Wang L, Zhou S, Chen X, Qian L, Zhang T, Sun X, Li M, Liu M, Guo Y, Hu Y, Ma Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157248
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157248
Loss of ARNTL Enhances ER Stress and Apoptosis in CKD Through Disruption of NRF2 Signaling.
He L, Zhang Q, Sheng X, Yin J, Yan Y, Wu M, Bao H, Hu S, Wang N, Cao A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70715
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70715
Study on the Mechanisms of Ischemic Stroke Impacting Sleep Homeostasis and Circadian Rhythms in Rats.
Chu TT, Sun C, Zheng YH, Gao WY, Zhao LL, Zhang JY
CNS neuroscience & therapeutics 2025 Feb;31(2):e70153
CNS neuroscience & therapeutics 2025 Feb;31(2):e70153
Vitamin B12 Protects Against Early Diabetic Kidney Injury and Alters Clock Gene Expression in Mice.
Wariyapperuma Appuhamillage NMW, Deshmukh AA, Moser RL, Ma Q, Zhou J, Li F, Kayashima Y, Maeda N
Biomolecules 2025 Dec 3;15(12)
Biomolecules 2025 Dec 3;15(12)
Inhibition of Circadian Rhythm Gene per1 Promotes Macrophage Infiltration in e‑Cigarette Aerosol-Induced Pulmonary Fibrosis in Mice.
Dong C, Li B, Liu C, Cui J, Li Y, Liang L, Song Y, Li X
Environment & health (Washington, D.C.) 2025 Aug 15;3(8):866-877
Environment & health (Washington, D.C.) 2025 Aug 15;3(8):866-877
Sulforaphane Improves Liver Metabolism and Gut Microbiota in Circadian Rhythm Disorder Mice Models Fed With High-Fat Diets.
He C, Chen M, Jiang X, Ren J, Ganapathiraju SV, Lei P, Yang H, Pannu PR, Zhao Y, Zhang X
Molecular nutrition & food research 2024 Nov;68(21):e2400535
Molecular nutrition & food research 2024 Nov;68(21):e2400535
Rhythm gene PER1 mediates ferroptosis and lipid metabolism through SREBF2/ALOX15 axis in polycystic ovary syndrome.
Chen Y, Liu Z, Chen H, Wen Y, Fan L, Luo M
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167182
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167182
Dysfunctional circadian clock accelerates cancer metastasis by intestinal microbiota triggering accumulation of myeloid-derived suppressor cells.
Liu JL, Xu X, Rixiati Y, Wang CY, Ni HL, Chen WS, Gong HM, Zhang ZL, Li S, Shen T, Li JM
Cell metabolism 2024 Jun 4;36(6):1320-1334.e9
Cell metabolism 2024 Jun 4;36(6):1320-1334.e9
Disruption of local circadian clocks in aristolochic acid-induced nephropathy in mice.
Xie D, Zhong S, Luo M, Xu J, Zheng R, Luo J, Wang Y, Guo Y, Guo L, Wu B, Lu D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156235
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156235
Uncovering the Novel Role of NR1D1 in Regulating BNIP3-Mediated Mitophagy in Ulcerative Colitis.
Chen Y, Li J, Li S, Cheng Y, Fu X, Li J, Zhu L
International journal of molecular sciences 2023 Sep 18;24(18)
International journal of molecular sciences 2023 Sep 18;24(18)
Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization.
Yao D, Li R, Hao J, Huang H, Wang X, Ran L, Fang Y, He Y, Wang W, Liu X, Wang M
Translational psychiatry 2023 Oct 6;13(1):310
Translational psychiatry 2023 Oct 6;13(1):310
In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA.
Reichlmeir M, Canet-Pons J, Koepf G, Nurieva W, Duecker RP, Doering C, Abell K, Key J, Stokes MP, Zielen S, Schubert R, Ivics Z, Auburger G
Cells 2023 Oct 3;12(19)
Cells 2023 Oct 3;12(19)
Prognostic risk factors of serous ovarian carcinoma based on mesenchymal stem cell phenotype and guidance for therapeutic efficacy.
Yang X, Zheng M, Ning Y, Sun J, Yu Y, Zhang S
Journal of translational medicine 2023 Jul 11;21(1):456
Journal of translational medicine 2023 Jul 11;21(1):456
Sleep Fragmentation, Electroencephalographic Slowing, and Circadian Disarray in a Mouse Model for Intensive Care Unit Delirium.
Dulko E, Jedrusiak M, Osuru HP, Atluri N, Illendula M, Davis EM, Beenhakker MP, Lunardi N
Anesthesia and analgesia 2023 Jul 1;137(1):209-220
Anesthesia and analgesia 2023 Jul 1;137(1):209-220
PER1 promotes functional recovery of mice with hindlimb ischemia by inducing anti-inflammatory macrophage polarization.
Ding Y, Wan S, Ma L, Wei K, Ye K
Biochemical and biophysical research communications 2023 Feb 12;644:62-69
Biochemical and biophysical research communications 2023 Feb 12;644:62-69
CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice.
Chen M, Zhang Y, Zeng S, Li D, You M, Zhang M, Wang Z, Wei L, Chen Y, Ruan XZ
iScience 2023 Apr 21;26(4):106524
iScience 2023 Apr 21;26(4):106524
Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model.
Naven MA, Zeef LAH, Li S, Humphreys PA, Smith CA, Pathiranage D, Cain S, Woods S, Bates N, Au M, Wen C, Kimber SJ, Meng QJ
Theranostics 2022;12(8):3963-3976
Theranostics 2022;12(8):3963-3976
The association between disruption of the circadian rhythm and aggravation of colitis in mice.
Chen YD, Zhao RF, Zheng G, Ling FM, Li JR, Xu MY, Guo D, Zhang QL, Li S, Zhu LR
Gastroenterology report 2022;10:goac028
Gastroenterology report 2022;10:goac028
Capsaicin Attenuates Oleic Acid-Induced Lipid Accumulation via the Regulation of Circadian Clock Genes in HepG2 Cells.
Li R, Xiao J, Cao Y, Huang Q, Ho CT, Lu M
Journal of agricultural and food chemistry 2022 Jan 26;70(3):794-803
Journal of agricultural and food chemistry 2022 Jan 26;70(3):794-803
PER1 as a Tumor Suppressor Attenuated in the Malignant Phenotypes of Breast Cancer Cells.
Liu Y, Hao J, Yuan G, Wei M, Bu Y, Jin T, Ma L
International journal of general medicine 2021;14:7077-7087
International journal of general medicine 2021;14:7077-7087
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Wan X, Zhu L, Zhao L, Peng L, Xiong J, Yang W, Yuan J, Liang F, Zhang K, Chen K
Cell death & disease 2021 Mar 19;12(4):301
Cell death & disease 2021 Mar 19;12(4):301
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice.
Chen S, Feng M, Zhang S, Dong Z, Wang Y, Zhang W, Liu C
Nature communications 2019 Aug 6;10(1):3518
Nature communications 2019 Aug 6;10(1):3518
Loss of circadian protein TIMELESS accelerates the progression of cellular senescence.
Shen X, Li M, Mao Z, Yu W
Biochemical and biophysical research communications 2018 Sep 18;503(4):2784-2791
Biochemical and biophysical research communications 2018 Sep 18;503(4):2784-2791
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 13463-1-AP(PER1 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using PER1 antibody 13463-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
