Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- AF283 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal Neuritin Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human Neuritin in direct ELISAs and Western blots.
- Reactivity
- Human, Rat
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Neuritin Up-regulates Kv4.2 α-Subunit of Potassium Channel Expression and Affects Neuronal Excitability by Regulating the Calcium-Calcineurin-NFATc4 Signaling Pathway.
Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease.
Neuritin mediates nerve growth factor-induced axonal regeneration and is deficient in experimental diabetic neuropathy.
Yao JJ, Zhao QR, Liu DD, Chow CW, Mei YA
The Journal of biological chemistry 2016 Aug 12;291(33):17369-81
The Journal of biological chemistry 2016 Aug 12;291(33):17369-81
Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease.
Choi Y, Lee K, Ryu J, Kim HG, Jeong AY, Woo RS, Lee JH, Hyun JW, Hahn S, Kim JH, Kim HS
PloS one 2014;9(8):e104121
PloS one 2014;9(8):e104121
Neuritin mediates nerve growth factor-induced axonal regeneration and is deficient in experimental diabetic neuropathy.
Karamoysoyli E, Burnand RC, Tomlinson DR, Gardiner NJ
Diabetes 2008 Jan;57(1):181-9
Diabetes 2008 Jan;57(1):181-9
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
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- Experimental details
- Detection of Human Neuritin by Western Blot. Western blot shows lysates of human brain (cerebellum) tissue and human kidney tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Rat Neuritin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF283) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for Neuritin at approximately 14 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.