Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12215-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- PDK3 antibody
- Antibody type
- Polyclonal
- Description
- PDK3 antibody (Cat. #12215-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mitophagy mitigates mitochondrial fatty acid β-oxidation deficient cardiomyopathy.
Lycorine hydrochloride interferes with energy metabolism to inhibit chemoresistant glioblastoma multiforme cell growth through suppressing PDK3.
NOTCH1 mitochondria localization during heart development promotes mitochondrial metabolism and the endothelial-to-mesenchymal transition in mice.
Acrolein exposure affects ovarian function by interfering with glycolysis and mitochondrial energy metabolism in mouse.
Therapeutic potential of microglial SMEK1 in regulating H3K9 lactylation in cerebral ischemia-reperfusion.
Overexpression of Pyruvate Dehydrogenase Kinase-3 Predicts Poor Prognosis in Urothelial Carcinoma.
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
Sun N, Barta H, Chaudhuri S, Chen K, Jin J, Luo H, Yang M, Krigman J, Zhang R, Sanghvi S, Sekine S, Sanders H, Kolonay D, Patel M, Baskin K, Singh H, Zhang P, Xin G, Finkel T
Nature communications 2025 Jul 1;16(1):5465
Nature communications 2025 Jul 1;16(1):5465
Lycorine hydrochloride interferes with energy metabolism to inhibit chemoresistant glioblastoma multiforme cell growth through suppressing PDK3.
Dong Q, Niu W, Mu M, Ye C, Wu P, Hu S, Niu C
Molecular and cellular biochemistry 2025 Jan;480(1):355-369
Molecular and cellular biochemistry 2025 Jan;480(1):355-369
NOTCH1 mitochondria localization during heart development promotes mitochondrial metabolism and the endothelial-to-mesenchymal transition in mice.
Wang J, Zhao R, Xu S, Zhou XY, Cai K, Chen YL, Zhou ZY, Sun X, Shi Y, Wang F, Gui YH, Tao H, Zhao JY
Nature communications 2024 Nov 16;15(1):9945
Nature communications 2024 Nov 16;15(1):9945
Acrolein exposure affects ovarian function by interfering with glycolysis and mitochondrial energy metabolism in mouse.
Chen YZ, Wang WK, Yang YF, Cheng SY, Li LF, Shen H, Qi ZM, Liu Y
Environmental pollution (Barking, Essex : 1987) 2024 Nov 15;361:124776
Environmental pollution (Barking, Essex : 1987) 2024 Nov 15;361:124776
Therapeutic potential of microglial SMEK1 in regulating H3K9 lactylation in cerebral ischemia-reperfusion.
Si WY, Yang CL, Wei SL, Du T, Li LK, Dong J, Zhou Y, Li H, Zhang P, Liu QJ, Duan RS, Duan RN
Communications biology 2024 Dec 26;7(1):1701
Communications biology 2024 Dec 26;7(1):1701
Overexpression of Pyruvate Dehydrogenase Kinase-3 Predicts Poor Prognosis in Urothelial Carcinoma.
Kuo YH, Chan TC, Lai HY, Chen TJ, Wu LC, Hsing CH, Li CF
Frontiers in oncology 2021;11:749142
Frontiers in oncology 2021;11:749142
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
Izquierdo-Garcia JL, Viswanath P, Eriksson P, Cai L, Radoul M, Chaumeil MM, Blough M, Luchman HA, Weiss S, Cairncross JG, Phillips JJ, Pieper RO, Ronen SM
Cancer research 2015 Aug 1;75(15):2999-3009
Cancer research 2015 Aug 1;75(15):2999-3009
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 12215-1-AP(PDK3 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The PDK3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDK3. This antibody recognizes human, mouse antigen. The PDK3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.