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- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 357308 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#357308, RRID:AB_2563086
- Product name
- PE/Cy7 anti-human Ganglioside GD2
- Antibody type
- Monoclonal
- Antigen
- Neuroblastoma cell line LAN-1
- Description
- Ganglioside GD2 is a sialic acid-containing glycosphingolipid involved in cell attachment to the extracellular matrix. Expression of GD2 in normal tissue is restricted to cells from the central nervous system, peripheral nerves, skin melanocytes, and mesenchymal stem cells. However GD2 is highly expressed by tumors of neuro-ectodermal origin such as melanomas, gliomas, neuroblastomas, and small cell lung carcinoma. GD2 has been proposed as a marker for some cancer stem cells.
- Reactivity
- Human
- Conjugate
- Near infrared dye
- Antibody clone number
- 14G2a
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human melanoma cell line M21 was stained with ganglioside GD2 (clone 14G2a) PE/Cy7 (filled histogram) or mouse IgG2a, κ PE/Cy7 isotype control (open histogram).
- Conjugate
- Near infrared dye
