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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- RA0265 - Provider product page
- Provider
- Oursmab
- Product name
- Dinutuximab (Biosimilar Reference Antibody) (Ganglioside GD2)
- Antibody type
- Monoclonal
- Description
- Dinutuximab is a chimeric monoclonal antibody approved for the treatment of high-risk neuroblastoma in pediatric patients. Marketed under the brand name Unituxin?, it is used as part of a multimodality regimen, including surgery, chemotherapy, and radiation, for children who have achieved at least a partial response to prior first-line therapy. Dinutuximab targets a specific antigen expressed on neuroblastoma cells and is administered via intravenous infusion. Its use is associated with significant side effects, including severe pain, capillary leak syndrome, and hypotension, requiring careful supportive management.
- Reactivity
- Human
- Isotype
- IgG
- Vial size
- 100 ¦Ìg,1 mg,5 mg-500,10 mg,25 mg,50 mg,161 mg
- Concentration
- Bottled at the concentration indicated on the vial.
- Storage
- Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
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Supportive validation
- Submitted by
- Oursmab (provider)
- Main image
- Experimental details
- Dinutuximab (Biosimilar Reference Antibody) (Ganglioside GD2)-RA0265-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.
Supportive validation
- Submitted by
- Oursmab (provider)
- Main image
- Experimental details
- ELISA plate pre-coated Antigen protein, can bind Dinutuximab (Biosimilar Reference Antibody) (Ganglioside GD2)-RA0265 in a linear range of 3.91-125 ng/mL.
