orb27644

PF4 antibody from Biorbyt
CXCL4, SCYB4

Antibody data

Product number
orb27644
Provider
Biorbyt
Proper citation
Biorbyt Cat#orb27644, RRID:AB_11018276
Product name
PF4 antibody
Provider product page
Biorbyt - orb27644
Antibody type
Polyclonal
Description
Rabbit Polyclonal to PF4. CXCL4, Chemokine (C-X-C motif) ligand 4, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. CXCL4 belongs to the CXC chemokine family. The CXCL4 gene contains 3 exons spanning approximately 1 kb. The gene is encoded on a 10-kb EcoRI fragment of genomic DNA. By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Vial size
100 μg
Concentration
500μg/ml.
Storage
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Provider Type Product Number
- No reagents -