21157-1-AP

antibody from Proteintech Group

Targeting: PF4 CXCL4, SCYB4

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

21157-1-AP

Provider

Proteintech Group

Product name

PF4 antibody

Antibody type

Polyclonal

Description

PF4 antibody (Cat. #21157-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, pig and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse, Porcine

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Mast Cell-Derived CXCL4: A Key Mediator of Ferroptosis and Cardiac Damage in Septic Cardiomyopathy.

Wei J, Jiang ZY, Ye LF, Lu HX
Immunity, inflammation and disease 2026 Mar;14(3):e70359

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Platelet Factor 4: A Novel Therapeutic Inhibitor for Experimental Neovascular Age-Related Macular Degeneration.

Ke X, Liang S, Qu T, Li S, Lei J, Han H, Guo Y, Xing M, Wang X, He S, Liao M, Zhou D, Yan H
Frontiers in bioscience (Landmark edition) 2026 Apr 23;31(4):49564

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Platelet activation stimulates macrophages to enhance ulcerative colitis through PF4/CXCR3 signaling.

Niu Y, Li A, Xu W, Zhang R, Mei R, Zhang L, Zhou F, Pan Q, Yan Y
International journal of molecular medicine 2025 May;55(5)

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Platelet factor 4-derived C15 peptide broadly inhibits enteroviruses by disrupting viral attachment.

Lv S, Li C, Pei Z, Hu Z, Du Y, Zheng B, Zhang W
Journal of virology 2025 Jan 31;99(1):e0185924

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Functions for platelet factor 4 (PF4/CXCL4) and its receptors in fibroblast-myofibroblast transition and fibrotic failure of arteriovenous fistulas (AVFs).

Xiao Y, Martinez L, Zigmond Z, Woltmann D, Singer DV, Singer HA, Vazquez-Padron RI, Salman LH
The journal of vascular access 2024 Nov;25(6):1911-1924

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Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF.

Song X, Wang L, Cai P, Xu Y, Liu Q, Fan D
Toxicology and applied pharmacology 2024 May;486:116938

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CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis.

Wei J, Peng MY, Wang SN, Lu HX
International immunopharmacology 2024 May 30;133:112096

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Regulatory Effects and Mechanisms of L-Theanine on Neurotransmitters via Liver-Brain Axis Under a High Protein Diet.

Xu W, Song Y, Xiao W, Gong Z
Molecular neurobiology 2024 Feb;61(2):783-798

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CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF-β1/Smad2/3 signaling in mouse viral myocarditis.

Wei J, Wang DF, Cui CC, Tan JJ, Peng MY, Lu HX
Immunity, inflammation and disease 2024 Apr;12(4):e1237

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Binding of serum-derived amyloid-associated proteins to amyloid fibrils.

Misumi Y, Tabata Y, Tasaki M, Obayashi K, Yamakawa S, Nomura T, Ueda M
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2023 Mar;30(1):67-73

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Chemokine PF4 Inhibits EV71 and CA16 Infections at the Entry Stage.

Pei Z, Wang H, Zhao Z, Chen X, Huan C, Zhang W
Journal of virology 2022 Jun 8;96(11):e0043522

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Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis.

Jin J, Qiao S, Liu J, Li W, Wang F, Gao X, Tian J, Wang N, Zhang J, Dong J, Li H, Wang J, Hu S, Zhou P
Cell & bioscience 2022 Jul 22;12(1):114

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ELF4 facilitates innate host defenses against Plasmodium by activating transcription of Pf4 and Ppbp.

Wang D, Zhang Z, Cui S, Zhao Y, Craft S, Fikrig E, You F
The Journal of biological chemistry 2019 May 10;294(19):7787-7796