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- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10061-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10061-1-AP, RRID:AB_2236537
- Product name
- OS9 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OS9 antibody (Cat. #10061-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting EGFR-binding protein SLC7A11 enhancing antitumor immunity of T cells via inducing MHC-I antigen presentation in nasopharyngeal carcinoma.
Chemical Glycoproteomic Profiling in Rice Seedlings Reveals N-glycosylation in the ERAD-L Machinery.
Proteomic characterization of endogenous substrates of mammalian ubiquitin ligase Hrd1.
Adult-onset obesity is triggered by impaired mitochondrial gene expression.
Endoplasmic reticulum lectin XTP3-B inhibits endoplasmic reticulum-associated degradation of a misfolded α1-antitrypsin variant.
SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates.
Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans.
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.
Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.
OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum.
Wang H, Fan S, Zhan Y, Xu Y, Du Y, Luo J, Zang H, Peng S, Wang W
Cell death & disease 2025 Jan 16;16(1):21
Cell death & disease 2025 Jan 16;16(1):21
Chemical Glycoproteomic Profiling in Rice Seedlings Reveals N-glycosylation in the ERAD-L Machinery.
Lei C, Li X, Li W, Chen Z, Liu S, Cheng B, Hu Y, Song Q, Qiu Y, Zhou Y, Meng X, Yu H, Zhou W, Chen X, Li J
Molecular & cellular proteomics : MCP 2025 Feb;24(2):100883
Molecular & cellular proteomics : MCP 2025 Feb;24(2):100883
Proteomic characterization of endogenous substrates of mammalian ubiquitin ligase Hrd1.
Ye Y, Baek SH, Ye Y, Zhang T
Cell & bioscience 2018;8:46
Cell & bioscience 2018;8:46
Adult-onset obesity is triggered by impaired mitochondrial gene expression.
Perks KL, Ferreira N, Richman TR, Ermer JA, Kuznetsova I, Shearwood AJ, Lee RG, Viola HM, Johnstone VPA, Matthews V, Hool LC, Rackham O, Filipovska A
Science advances 2017 Aug;3(8):e1700677
Science advances 2017 Aug;3(8):e1700677
Endoplasmic reticulum lectin XTP3-B inhibits endoplasmic reticulum-associated degradation of a misfolded α1-antitrypsin variant.
Fujimori T, Kamiya Y, Nagata K, Kato K, Hosokawa N
The FEBS journal 2013 Mar;280(6):1563-75
The FEBS journal 2013 Mar;280(6):1563-75
SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates.
Iida Y, Fujimori T, Okawa K, Nagata K, Wada I, Hosokawa N
The Journal of biological chemistry 2011 May 13;286(19):16929-39
The Journal of biological chemistry 2011 May 13;286(19):16929-39
Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans.
Hosokawa N, Kamiya Y, Kamiya D, Kato K, Nagata K
The Journal of biological chemistry 2009 Jun 19;284(25):17061-17068
The Journal of biological chemistry 2009 Jun 19;284(25):17061-17068
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.
Christianson JC, Shaler TA, Tyler RE, Kopito RR
Nature cell biology 2008 Mar;10(3):272-82
Nature cell biology 2008 Mar;10(3):272-82
Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.
Hosokawa N, Wada I, Nagasawa K, Moriyama T, Okawa K, Nagata K
The Journal of biological chemistry 2008 Jul 25;283(30):20914-24
The Journal of biological chemistry 2008 Jul 25;283(30):20914-24
OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum.
Wang Y, Fu X, Gaiser S, Köttgen M, Kramer-Zucker A, Walz G, Wegierski T
The Journal of biological chemistry 2007 Dec 14;282(50):36561-70
The Journal of biological chemistry 2007 Dec 14;282(50):36561-70
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10061-1-AP(OS9 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The OS9 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human OS9. This antibody recognizes human antigen. The OS9 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
