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- Antibody Data
- Antigen structure
- References [18]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 13714-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13714-1-AP, RRID:AB_2091076
- Product name
- DMC1 antibody
- Antibody type
- Polyclonal
- Description
- DMC1 antibody (Cat. #13714-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids.
Polyethylene terephthalate (PET) microplastics induced male reproductive toxicity in mice by activating the p38-MAPK pathway.
m(6)A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post-Transcriptional Control.
Testis-Specific PDHA2 Is Required for Proper Meiotic Recombination and Chromosome Organisation During Spermatogenesis.
Biallelic BRCA2 variants induce premature ovarian insufficiency by impaired meiotic homologous recombination.
Protein disulfide isomerase is essential for spermatogenesis in mice.
ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression.
Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination.
Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice.
ATF7IP2, a meiosis-specific partner of SETDB1, is required for proper chromosome remodeling and crossover formation during spermatogenesis.
NAT10-mediated N4-acetylcytidine modification is required for meiosis entry and progression in male germ cells.
MEIOK21 regulates oocyte quantity and quality via modulating meiotic recombination.
MRNIP is essential for meiotic progression and spermatogenesis in mice.
A Prognostic Prediction Model Developed Based on Four CpG Sites and Weighted Correlation Network Analysis Identified DNAJB1 as a Novel Biomarker for Pancreatic Cancer.
NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis.
MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis.
A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1.
The Ectopic Expression of Meiosis Regulatory Genes in Cutaneous T-Cell Lymphomas (CTCL).
Sun J, Zhu L, Li Y, Tang J, Zhang T, Zhang H, Wang W, Li L, Bian S, Wu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e12670
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e12670
Polyethylene terephthalate (PET) microplastics induced male reproductive toxicity in mice by activating the p38-MAPK pathway.
Zhang X, Ma T, Sun J, Fang Y, Wang Y, Li X, Zhao Z, Su N, Liu M, Bai J, Liu J, Wu J
Ecotoxicology and environmental safety 2025 Sep 1;302:118756
Ecotoxicology and environmental safety 2025 Sep 1;302:118756
m(6)A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post-Transcriptional Control.
Yin L, Zhang Y, Zhang B, Zhang J, Xiong M, Jiang N, Xiao J, Gao H, Xiong W, Wang X, Wang F, Yuan S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06600
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06600
Testis-Specific PDHA2 Is Required for Proper Meiotic Recombination and Chromosome Organisation During Spermatogenesis.
Wang G, Fang K, Shang Y, Zhou X, Shao Q, Li S, Wang P, Chen CD, Zhang L, Wang S
Cell proliferation 2025 Jul;58(7):e70003
Cell proliferation 2025 Jul;58(7):e70003
Biallelic BRCA2 variants induce premature ovarian insufficiency by impaired meiotic homologous recombination.
Wu X, Zhang Q, Li C, Zhuang S, Liu H, Jiao X, Zhao S, Qin Y, Guo T
Communications biology 2025 Jul 25;8(1):1104
Communications biology 2025 Jul 25;8(1):1104
Protein disulfide isomerase is essential for spermatogenesis in mice.
Zhang Y, Yang A, Zhao Z, Chen F, Yan X, Han Y, Wu D, Wu Y
JCI insight 2024 Jun 24;9(12)
JCI insight 2024 Jun 24;9(12)
ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression.
Zhou X, Fang K, Liu Y, Li W, Tan Y, Zhang J, Yu X, Wang G, Zhang Y, Shang Y, Zhang L, Chen CD, Wang S
Cell proliferation 2024 Apr;57(4):e13567
Cell proliferation 2024 Apr;57(4):e13567
Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination.
Huang Y, Li L, An G, Yang X, Cui M, Song X, Lin J, Zhang X, Yao Z, Wan C, Zhou C, Zhao J, Song K, Ren S, Xia X, Fu X, Lan Y, Hu X, Wang W, Wang M, Zheng Y, Miao K, Bai X, Hutchins AP, Chang G, Gao S, Zhao XY
Nature cell biology 2023 Oct;25(10):1520-1534
Nature cell biology 2023 Oct;25(10):1520-1534
Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice.
Davies B, Zhang G, Moralli D, Alghadban S, Biggs D, Preece C, Donnelly P, Hinch AG
Genome research 2023 Dec 1;33(11):2018-2027
Genome research 2023 Dec 1;33(11):2018-2027
ATF7IP2, a meiosis-specific partner of SETDB1, is required for proper chromosome remodeling and crossover formation during spermatogenesis.
Shao Q, Zhang Y, Liu Y, Shang Y, Li S, Liu L, Wang G, Zhou X, Wang P, Gao J, Zhou J, Zhang L, Wang S
Cell reports 2023 Aug 29;42(8):112953
Cell reports 2023 Aug 29;42(8):112953
NAT10-mediated N4-acetylcytidine modification is required for meiosis entry and progression in male germ cells.
Chen L, Wang WJ, Liu Q, Wu YK, Wu YW, Jiang Y, Liao XQ, Huang F, Li Y, Shen L, Yu C, Zhang SY, Yan LY, Qiao J, Sha QQ, Fan HY
Nucleic acids research 2022 Oct 28;50(19):10896-10913
Nucleic acids research 2022 Oct 28;50(19):10896-10913
MEIOK21 regulates oocyte quantity and quality via modulating meiotic recombination.
Shang Y, Huang J, Li W, Zhang Y, Zhou X, Shao Q, Tan T, Yin S, Zhang L, Wang S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22357
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jun;36(6):e22357
MRNIP is essential for meiotic progression and spermatogenesis in mice.
Lin M, Lv J, Zhao D, Liu S, Xu J, Wu Y, Wang F, Zhang J, Zheng B, Shen C, Guan X, Yu J, Huang X
Biochemical and biophysical research communications 2021 Apr 23;550:127-133
Biochemical and biophysical research communications 2021 Apr 23;550:127-133
A Prognostic Prediction Model Developed Based on Four CpG Sites and Weighted Correlation Network Analysis Identified DNAJB1 as a Novel Biomarker for Pancreatic Cancer.
Kong L, Liu P, Fei X, Wu T, Wang Z, Zhang B, Li J, Tan X
Frontiers in oncology 2020;10:1716
Frontiers in oncology 2020;10:1716
NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis.
Zhang B, Tang Z, Li L, Lu LY
Cell death and differentiation 2020 Jul;27(7):2176-2190
Cell death and differentiation 2020 Jul;27(7):2176-2190
MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis.
Shang Y, Huang T, Liu H, Liu Y, Liang H, Yu X, Li M, Zhai B, Yang X, Wei Y, Wang G, Chen Z, Wang S, Zhang L
Nucleic acids research 2020 Jul 9;48(12):6624-6639
Nucleic acids research 2020 Jul 9;48(12):6624-6639
A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1.
Felipe-Medina N, Caburet S, Sánchez-Sáez F, Condezo YB, de Rooij DG, Gómez-H L, Garcia-Valiente R, Todeschini AL, Duque P, Sánchez-Martin MA, Shalev SA, Llano E, Veitia RA, Pendás AM
eLife 2020 Aug 26;9
eLife 2020 Aug 26;9
The Ectopic Expression of Meiosis Regulatory Genes in Cutaneous T-Cell Lymphomas (CTCL).
Gantchev J, Martínez Villarreal A, Xie P, Lefrançois P, Gunn S, Netchiporouk E, Sasseville D, Litvinov IV
Frontiers in oncology 2019;9:429
Frontiers in oncology 2019;9:429
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse spermatophore tissue were subjected to SDS PAGE followed by western blot with 13714-1-AP(DMC1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DMC1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DMC1. This antibody recognizes human,mouse,rat antigen. The DMC1 antibody has been validated for the following applications: ELISA, WB, IHC, IF, IP analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-DMC1 (IP:13714-1-AP, 3ug; Detection:13714-1-AP 1:600) with mouse testis tissue lysate 4800ug.
- Sample type
- tissue
