Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA021945 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA021945, RRID:AB_1847928
- Product name
- Anti-DYSF
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human DYSF, Gene description: dysferlin, Alternative Gene Names: FER1L1, LGMD2B, Validated applications: IHC, Uniprot ID: O75923, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Membrane fusion FerA domains enhance adeno-associated virus vector transduction
Enzymatic cleavage of myoferlin releases a dual C2-domain module linked to ERK signalling
Limited proteolysis as a tool to probe the tertiary conformation of dysferlin and structural consequences of patient missense variant L344P
Zhang X, Anthony B, Chai Z, Lee Dobbins A, Sutton R, Li C
Biomaterials 2020;241
Biomaterials 2020;241
Enzymatic cleavage of myoferlin releases a dual C2-domain module linked to ERK signalling
Piper A, Ross S, Redpath G, Lemckert F, Woolger N, Bournazos A, Greer P, Sutton R, Cooper S
Cellular Signalling 2017;33
Cellular Signalling 2017;33
Limited proteolysis as a tool to probe the tertiary conformation of dysferlin and structural consequences of patient missense variant L344P
Woolger N, Bournazos A, Sophocleous R, Evesson F, Lek A, Driemer B, Sutton R, Cooper S
Journal of Biological Chemistry 2017;292(45):18577-18591
Journal of Biological Chemistry 2017;292(45):18577-18591
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human skeletal muscle and skin tissues using HPA021945 antibody. Corresponding DYSF RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol