A01234-1

antibody from Boster Biological Technology
Targeting: DYSF FER1L1, LGMD2B
Provider product page for A01234-1

Antibody data

Product number
A01234-1 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-Dysferlin Antibody
Antibody type
Polyclonal
Description
Polyclonal antibody for DYSFERLIN/DYSF detection. Host: Rabbit.Size: 100μl. Tested applications: WB. Reactive species: Human. DYSFERLIN/DYSF information: Molecular Weight: 237295 MW; Subcellular Localization: Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasmic vesicle membrane ; Single-pass type II membrane protein . Cell membrane. Colocalizes, during muscle differentiation, with BIN1 in the T-tubule system of myotubules and at the site of contact between two myotubes or a myoblast and a myotube. Wounding of myotubes led to its focal enrichment to the site of injury and to its relocalization in a Ca(2+)-dependent manner toward the plasma membrane. Colocalizes with AHNAK, AHNAK2 and PARVB at the sarcolemma of skeletal muscle. Detected on the apical plasma membrane of the syncytiotrophoblast. Reaches the plasmma membrane through a caveolin-independent mechanism. Retained by caveolin at the plasmma membrane (By similarity). Colocalizes, during muscle differentiation, with CACNA1S in the T-tubule system of myotubules (By similarity). Accumulates and colocalizes with fusion vesicles at the sarcolemma disruption sites (By similarity); Tissue Specificity: Expressed in skeletal muscle, myoblast, myotube and in the syncytiotrophoblast (STB) of the placenta (at protein level). Ubiquitous. Highly expressed in skeletal muscle. Also found in heart, brain, spleen, intestine, placenta and at lower levels in liver, lung, kidney and pancreas.
Reactivity
Human, Mouse
Host
Rabbit
Vial size
100μl
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquoted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.
DYSF protein structure - A01234-1 shown in red.