Explore
Validate
LearnPA5-40407
antibody from Invitrogen Antibodies
Targeting: ARX
CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS
Western blot
Other assayAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Other assay [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PA5-40407 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- ARX Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Peptide sequence: AAGGGTGTED DEEELLEDEE DEDEEEELLE DDEEELLEDD ARALLKEPRR Sequence homology: Dog: 92%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.5 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Estrogen Treatment Reverses Prematurity-Induced Disruption in Cortical Interneuron Population.
Panda S, Dohare P, Jain S, Parikh N, Singla P, Mehdizadeh R, Klebe DW, Kleinman GM, Cheng B, Ballabh P
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Aug 22;38(34):7378-7391
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Aug 22;38(34):7378-7391
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 6. Estrogen (E2) treatment elevates Arx, Shox2, and Gad65/67 levels. A , Data are shown as mean +- SEM ( n = 5 each group). mRNA expression of Arx , Shox2 , and Gad1 was higher in E2-treated kits relative to controls as indicted. GAD2 and Lhx6 were comparable between the two groups. B , Representative Western blot analyses for Arx, Lmo3, Sox6, and Dlx1 in brain homogenates from E2- and vehicle-treated kits at P3 and P7. Data are shown as mean +- SEM ( n = 5 each group). The protein levels were comparable between E2-treated kits relative to controls at both P3 and P7. C , Representative Western blot analyses for Arx, Lmo3, CXCR4, Gad65, and Gad67 in brain homogenates from E2- and vehicle-treated kits at P14. Data are shown as mean +- SEM ( n = 5 each group). Arx and GAD65 protein level was higher in E2-treated kits relative to controls at P14, whereas Lmo3 was reduced in E2-treated kits compared with controls. * p < 0.05, ** p < 0.01 for E2- versus vehicle-treated kits.
