Tissue expression
Cell line expression
Protein structure
ST6GALNAC4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4SIAT3C, SIAT7D, ST6GALNACIV
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ABIN2503660 | Polyclonal |
WB
IHC
FC
|
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Abnova Corporation | PAB20469 | Polyclonal |
ICC
IHC |
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NSJ Bioreagents | RQ7863 | Polyclonal |
WB
EL |
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Biorbyt | orb1241040 | Polyclonal |
WB
EL |
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Aviva Systems Biology | ARP49121_P050 | Polyclonal |
WB
|
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