Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 17222-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17222-1-AP, RRID:AB_2284990
- Product name
- RIOK1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RIOK1 antibody (Cat. #17222-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Productive mRNA chromatin escape is promoted by PRMT5 activity.
Pentose phosphate recycling driven by Gli1 contributes to chemotherapy resistance in cancer cells.
RIOK1 phase separation restricts PTEN translation via stress granules activating tumor growth in hepatocellular carcinoma.
RIOK3 mediates the degradation of 40S ribosomes.
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Elevated Expression of RIOK1 Is Correlated with Breast Cancer Hormone Receptor Status and Promotes Cancer Progression.
Ras Post-transcriptionally Enhances a Pre-malignantly Primed EMT to Promote Invasion.
DeAngelo JD, Maron MI, Roth JS, Hegde S, Silverstein AM, Gupta V, Stransky S, Basken J, Azofeifa J, Query CC, Sidoli S, Gamble MJ, Shechter D
Molecular cell 2025 Nov 6;85(21):4016-4031.e9
Molecular cell 2025 Nov 6;85(21):4016-4031.e9
Pentose phosphate recycling driven by Gli1 contributes to chemotherapy resistance in cancer cells.
Hu Q, Jiang C, Qin Y, Li B, Wang J, Wang T, Ji S, Ye Z, Dang Q, Liu M, Yu X, Xu X
Cancer letters 2025 May 28;618:217633
Cancer letters 2025 May 28;618:217633
RIOK1 phase separation restricts PTEN translation via stress granules activating tumor growth in hepatocellular carcinoma.
Meng F, Li H, Huang Y, Wang C, Liu Y, Zhang C, Chen D, Zeng T, Zhang S, Li Y, Zhang B, Lang C, Xia J, Xiong W, Pan S, Sun X, Thorne RF, Liu Y, Wang J, Zhang S, Song R, Wang J, Liu L
Nature cancer 2025 Jul;6(7):1223-1241
Nature cancer 2025 Jul;6(7):1223-1241
RIOK3 mediates the degradation of 40S ribosomes.
Huang Z, Diehl FF, Wang M, Li Y, Song A, Chen FX, Rosa-Mercado NA, Beckmann R, Green R, Cheng J
Molecular cell 2025 Feb 20;85(4):802-814.e12
Molecular cell 2025 Feb 20;85(4):802-814.e12
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Yu M, Hu X, Yan J, Wang Y, Lu F, Chang J
Biomedicines 2021 Sep 17;9(9)
Biomedicines 2021 Sep 17;9(9)
Elevated Expression of RIOK1 Is Correlated with Breast Cancer Hormone Receptor Status and Promotes Cancer Progression.
Huang Z, Li X, Xie T, Gu C, Ni K, Yin Q, Cao X, Zhang C
Cancer research and treatment 2020 Oct;52(4):1067-1083
Cancer research and treatment 2020 Oct;52(4):1067-1083
Ras Post-transcriptionally Enhances a Pre-malignantly Primed EMT to Promote Invasion.
Bisogno LS, Friedersdorf MB, Keene JD
iScience 2018 Jun 29;4:97-108
iScience 2018 Jun 29;4:97-108
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The RIOK1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RIOK1. This antibody recognizes human, mouse, rat antigen. The RIOK1 antibody has been validated for the following applications: ELISA, WB analysis.