Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA014245 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA014245, RRID:AB_1848495
- Product name
- Anti-MYOF
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human MYOF, Gene description: myoferlin, Alternative Gene Names: FER1L3, KIAA1207, Validated applications: ICC, WB, IHC, Uniprot ID: Q9NZM1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Identification of myoferlin as a mitochondria-associated membranes component required for calcium signaling in PDAC cell lines
HBZ upregulates myoferlin expression to facilitate HTLV-1 infection
Myoferlin disturbs redox equilibrium to accelerate gastric cancer migration
Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth
Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity through the Control of Oxidative Phosphorylation
Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling
Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness
A muscle-specific protein ‘myoferlin’ modulates IL-6/STAT3 signaling by chaperoning activated STAT3 to nucleus
Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes
Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development
Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer
Loss of Myoferlin Redirects Breast Cancer Cell Motility towards Collective Migration
Isolation and Characterization of Progenitor-Like Cells from Human Renal Proximal Tubules
Anania S, Farnir M, Peiffer R, Boumahd Y, Thiry M, Agirman F, Maloujahmoum N, Bellahcène A, Peulen O
Cell Communication and Signaling 2024;22(1)
Cell Communication and Signaling 2024;22(1)
HBZ upregulates myoferlin expression to facilitate HTLV-1 infection
Bangham C, Polakowski N, Sarker M, Hoang K, Boateng G, Rushing A, Kendle W, Pique C, Green P, Panfil A, Lemasson I
PLOS Pathogens 2023;19(2):e1011202
PLOS Pathogens 2023;19(2):e1011202
Myoferlin disturbs redox equilibrium to accelerate gastric cancer migration
Shi H, Cheng Y, Shi Q, Liu W, Yang X, Wang S, Wei L, Chen X, Fang H
Frontiers in Oncology 2022;12
Frontiers in Oncology 2022;12
Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth
Gupta S, Yano J, Mercier V, Htwe H, Shin H, Rademaker G, Cakir Z, Ituarte T, Wen K, Kim G, Zoncu R, Roux A, Dawson D, Perera R
Nature Cell Biology 2021;23(3):232-242
Nature Cell Biology 2021;23(3):232-242
Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
Anania S, Peiffer R, Rademaker G, Hego A, Thiry M, Deldicque L, Francaux M, Maloujahmoum N, Agirman F, Bellahcène A, Castronovo V, Peulen O
Cancers 2020;12(6):1643
Cancers 2020;12(6):1643
Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity through the Control of Oxidative Phosphorylation
Rademaker G, Costanza B, Anania S, Agirman F, Maloujahmoum N, Di Valentin E, Goval J, Bellahcène A, Castronovo V, Peulen O
Cancers 2019;11(6):853
Cancers 2019;11(6):853
Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-β1 signaling
Barnhouse V, Weist J, Shukla V, Ghadiali S, Kniss D, Leight J
Oncotarget 2018;9(27):19209-19222
Oncotarget 2018;9(27):19209-19222
Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness
Rademaker G, Hennequière V, Brohée L, Nokin M, Lovinfosse P, Durieux F, Gofflot S, Bellier J, Costanza B, Herfs M, Peiffer R, Bettendorff L, Deroanne C, Thiry M, Delvenne P, Hustinx R, Bellahcène A, Castronovo V, Peulen O
Oncogene 2018;37(32):4398-4412
Oncogene 2018;37(32):4398-4412
A muscle-specific protein ‘myoferlin’ modulates IL-6/STAT3 signaling by chaperoning activated STAT3 to nucleus
Yadav A, Kumar B, Lang J, Teknos T, Kumar P
Oncogene 2017;36(46):6374-6382
Oncogene 2017;36(46):6374-6382
Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes
Blomme A, Fahmy K, Peulen O, Costanza B, Fontaine M, Struman I, Baiwir D, de Pauw E, Thiry M, Bellahcène A, Castronovo V, Turtoi A
Oncotarget 2016;7(50):83669-83683
Oncotarget 2016;7(50):83669-83683
Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development
Bhattacharyya S, Rainey M, Arya P, Mohapatra B, Mushtaq I, Dutta S, George M, Storck M, McComb R, Muirhead D, Todd G, Gould K, Datta K, Waes J, Band V, Band H
Scientific Reports 2016;6(1)
Scientific Reports 2016;6(1)
Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer
Blomme A, Costanza B, de Tullio P, Thiry M, Van Simaeys G, Boutry S, Doumont G, Di Valentin E, Hirano T, Yokobori T, Gofflot S, Peulen O, Bellahcène A, Sherer F, Le Goff C, Cavalier E, Mouithys-Mickalad A, Jouret F, Cusumano P, Lifrange E, Muller R, Goldman S, Delvenne P, De Pauw E, Nishiyama M, Castronovo V, Turtoi A
Oncogene 2016;36(15):2116-2130
Oncogene 2016;36(15):2116-2130
Loss of Myoferlin Redirects Breast Cancer Cell Motility towards Collective Migration
Li J, Volakis L, Li R, Ackerman W, Mihai C, Bechel M, Summerfield T, Ahn C, Powell H, Zielinski R, Rosol T, Ghadiali S, Kniss D
PLoS ONE 2014;9(2):e86110
PLoS ONE 2014;9(2):e86110
Isolation and Characterization of Progenitor-Like Cells from Human Renal Proximal Tubules
Lindgren D, Boström A, Nilsson K, Hansson J, Sjölund J, Möller C, Jirström K, Nilsson E, Landberg G, Axelson H, Johansson M
The American Journal of Pathology 2011;178(2):828-837
The American Journal of Pathology 2011;178(2):828-837
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human urinary bladder and skeletal muscle tissues using HPA014245 antibody. Corresponding MYOF RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol