19673-1-AP

antibody from Proteintech Group

Targeting: MYH10 NMMHCB

Provider product page for 19673-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [22]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 19673-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#19673-1-AP, RRID:AB_10858231
Product name: MYH10-Specific antibody
Antibody type: Polyclonal
Description: MYH10-Specific antibody (Cat. #19673-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

MYH10 protein structure - 19673-1-AP shown in red.

Submitted references Disulfidptosis-Related Genes as Novel Biomarkers and Therapeutic Targets in Dilated Cardiomyopathy.

Bo X, Fan J, Xu S, Zeng Y, Xu A, Wang X, Wang H, Kang P, Fu Y, Fan H, Tan X, Zhou Y
Journal of inflammation research 2025;18:9967-9988

The Improved-EFI Score: A Multi-Omics-Based Novel Efficacy Predictive Tool for Predicting the Natural Fertility of Endometriosis Patients.

He Q, Zhang C, Hu Y, Deng J, Zhang S
International journal of general medicine 2025;18:881-895

A Novel Disulfidptosis-Related Diagnostic Gene Signature and Differential Expression Validation in Ischaemic Cardiomyopathy.

Tan X, Xu S, Zeng Y, Yu F, Qin Z, Zhang G, Fan J, Bo X, Tang J, Fan H, Zhou Y
Journal of cellular and molecular medicine 2025 Mar;29(5):e70475

Systematic interrogation of functional genes underlying cholesterol and lipid homeostasis.

Shan H, Fan S, Li Q, Liang R, Chen Z, Wang S, Wang X, Li Y, Chen S, Yu K, Fei T
Genome biology 2025 Mar 17;26(1):59

Disulfidptosis links the pathophysiology of ulcerative colitis and immune infiltration in colon adenocarcinoma.

Jiang C, Yue T, Jia Z, Song L, Zeng X, Bao Z, Li X, Cui Z, Mi W, Li Q
Scientific reports 2025 Feb 13;15(1):5365

The Mechanism of Matrilin-2 Inhibiting the Progression of In-Stent Restenosis for Lower Extremity Arteriosclerosis Obliterans via TGF-β/Smad Signaling Pathway.

Li M, Ma C, Yin K, Lu F, Lu Z, Wang N, Zhang L, He Y, Dong J
Annals of vascular surgery 2025 Dec;121:65-72

Microfilament-Myosin II Regulates the Differentiation of Multinucleated Cysts into Oocytes and Influences Oocyte Developmental Potential in Mice.

Xu R, Pan M, Zheng Z, Tang Y, Yan Y, Lu S, Peng S, Ma B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e00358

Mutations in CFAP57 disrupt the localization of MYH10 and IFT88, leading to flagellogenesis failure in humans and mice.

Chen Y, Li L, Meng R, Li S, Li Y, Jiang Z, Xu D, Lu Z, Yin C, Sha Y, Wang F
Human genomics 2025 Dec 29;19(1):152

Integrated bioinformatic analysis of immune infiltration and disulfidptosis related gene subgroups in type A aortic dissection.

Wang D, Wang C, Liu H, Zhang Z, Li M, Ge X, Bi A, Gao C, Tian X, Liu K, Zhu Z
Scientific reports 2025 Apr 21;15(1):13719

Exploring the diagnostic and immune infiltration roles of disulfidptosis related genes in pulmonary hypertension.

Tan X, Zhang N, Zhang G, Xu S, Zeng Y, Bian F, Tang B, Wang H, Fan J, Bo X, Fu Y, Fan H, Zhou Y, Kang P
Respiratory research 2024 Oct 9;25(1):365

Identification and validation of differentially expressed disulfidptosis-related genes in hypertrophic cardiomyopathy.

Fan H, Tan X, Xu S, Zeng Y, Zhang H, Shao T, Zhao R, Zhou P, Bo X, Fan J, Fu Y, Ding X, Zhou Y
Molecular medicine (Cambridge, Mass.) 2024 Dec 19;30(1):249

TMEFF1 is a neuron-specific restriction factor for herpes simplex virus.

Dai Y, Idorn M, Serrero MC, Pan X, Thomsen EA, Narita R, Maimaitili M, Qian X, Iversen MB, Reinert LS, Flygaard RK, Chen M, Ding X, Zhang BC, Carter-Timofte ME, Lu Q, Jiang Z, Zhong Y, Zhang S, Da L, Zhu J, Denham M, Nissen P, Mogensen TH, Mikkelsen JG, Zhang SY, Casanova JL, Cai Y, Paludan SR
Nature 2024 Aug;632(8024):383-389

Mechanosensitive accumulation of non-muscle myosin IIB during mitosis requires its translocation activity.

Wang C, Ding J, Wei Q, Du S, Gong X, Chew TG
iScience 2023 Oct 20;26(10):107773

Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics.

Xu H, Bensalel J, Raju S, Capobianco E, Lu ML, Wei J
Journal of neurochemistry 2023 Feb;164(4):512-528

Decreased mitochondrial function in UVA-irradiated dermal fibroblasts causes the insufficient formation of type I collagen and fibrillin-1 fibers.

Katsuyama Y, Yamawaki Y, Sato Y, Muraoka S, Yoshida M, Okano Y, Masaki H
Journal of dermatological science 2022 Oct;108(1):22-29

Nidogen1-enriched extracellular vesicles accelerate angiogenesis and bone regeneration by targeting Myosin-10 to regulate endothelial cell adhesion.

Cheng P, Cao T, Zhao X, Lu W, Miao S, Ning F, Wang D, Gao Y, Wang L, Pei G, Yang L
Bioactive materials 2022 Jun;12:185-197

ET(A)R silencing ameliorated neurovascular injury after SAH in rats through ERK/KLF4-mediated phenotypic transformation of smooth muscle cells.

Zhang Z, Chen H, Liu L, Zhao G, He J, Liu H, Zhou C, Liu X, Sun X, Guo Z
Experimental neurology 2021 Mar;337:113596

p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi.

Tan X, Banerjee P, Shi L, Xiao GY, Rodriguez BL, Grzeskowiak CL, Liu X, Yu J, Gibbons DL, Russell WK, Creighton CJ, Kurie JM
Science advances 2021 Jun;7(25)

Bexarotene Exerts Protective Effects Through Modulation of the Cerebral Vascular Smooth Muscle Cell Phenotypic Transformation by Regulating PPARγ/FLAP/LTB(4) After Subarachnoid Hemorrhage in Rats.

Zhang Z, Zhao G, Liu L, He J, Darwazeh R, Liu H, Chen H, Zhou C, Guo Z, Sun X
Cell transplantation 2019 Sep-Oct;28(9-10):1161-1172

Angiotensin II-mediated MYH9 downregulation causes structural and functional podocyte injury in diabetic kidney disease.

Kang JS, Lee SJ, Lee JH, Kim JH, Son SS, Cha SK, Lee ES, Chung CH, Lee EY
Scientific reports 2019 May 22;9(1):7679

Magnesium Sulfate-Mediated Vascular Relaxation and Calcium Channel Activity in Placental Vessels Different From Nonplacental Vessels.

Tang J, He A, Li N, Chen X, Zhou X, Fan X, Liu Y, Zhang M, Qi L, Tao J, Sun M, Xu Z
Journal of the American Heart Association 2018 Jul 12;7(14)

Mutations of MYH14 are associated to anorectal malformations with recto-perineal fistulas in a small subset of Chinese population.

Zhu Z, Peng L, Chen G, Jiang W, Shen Z, Du C, Zang R, Su Y, Xie H, Li H, Xia Y, Tang W
Clinical genetics 2017 Nov;92(5):503-509

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse brain tissue were subjected to SDS PAGE followed by western blot with 19673-1-AP(MYH10-Specific antibody) at dilution of 1:1000
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using MYH10 antibody 19673-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line