Tissue expression
Cell line expression

PRCP

gene product
HUMPCP, PCP 
This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
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258 antibodies from 26 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
1 antibody
LifeSpan BioSciences, Inc.
55 antibodies
Biorbyt
27 antibodies
antibodies-online
73 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Invitrogen Antibodies
7 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
OriGene
2 antibodies
Novus Biologicals
5 antibodies
Aviva Systems Biology
2 antibodies
Abgent
2 antibodies
Atlas Antibodies
1 antibody
Boster Biological Technology
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abnova Corporation
3 antibodies
R&D Systems
2 antibodies
MyBioSource
6 antibodies
ProSci
1 antibody
Abbexa
9 antibodies
United States Biological
28 antibodies
Creative Diagnostics
2 antibodies
Leading Biology
2 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Creative Biolabs
1 antibody