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Learn20641-1-AP
antibody from Proteintech Group
Targeting: RMDN3
FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 20641-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20641-1-AP, RRID:AB_10695187
- Product name
- PTPIP51 antibody
- Antibody type
- Polyclonal
- Description
- PTPIP51 antibody (Cat. #20641-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Development of a signal-integrating reporter to monitor mitochondria-ER contacts.
Mitochondria-associated endoplasmic reticulum membranes tethering protein VAPB-PTPIP51 protects against ischemic stroke through inhibiting the activation of autophagy.
Disruption of Mitochondrial-associated ER membranes by HIV-1 tat protein contributes to premature brain aging.
ER-mitochondria contacts and cholesterol metabolism are disrupted by disease-associated tau protein.
PTPIP51 inhibits non-small-cell lung cancer by promoting PTEN-mediated EGFR degradation.
Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate autophagy.
The role of Mfn2 in the structure and function of endoplasmic reticulum-mitochondrial tethering in vivo.
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
A High-Density Human Mitochondrial Proximity Interaction Network.
Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation.
The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.
Yang Z, Chan DC
bioRxiv : the preprint server for biology 2024 Feb 14;
bioRxiv : the preprint server for biology 2024 Feb 14;
Mitochondria-associated endoplasmic reticulum membranes tethering protein VAPB-PTPIP51 protects against ischemic stroke through inhibiting the activation of autophagy.
Li M, Zhang Y, Yu G, Gu L, Zhu H, Feng S, Xiong X, Jian Z
CNS neuroscience & therapeutics 2024 Apr;30(4):e14707
CNS neuroscience & therapeutics 2024 Apr;30(4):e14707
Disruption of Mitochondrial-associated ER membranes by HIV-1 tat protein contributes to premature brain aging.
Arjona SP, Allen CNS, Santerre M, Gross S, Soboloff J, Booze R, Sawaya BE
CNS neuroscience & therapeutics 2023 Jan;29(1):365-377
CNS neuroscience & therapeutics 2023 Jan;29(1):365-377
ER-mitochondria contacts and cholesterol metabolism are disrupted by disease-associated tau protein.
Szabo L, Cummins N, Paganetti P, Odermatt A, Papassotiropoulos A, Karch C, Götz J, Eckert A, Grimm A
EMBO reports 2023 Aug 3;24(8):e57499
EMBO reports 2023 Aug 3;24(8):e57499
PTPIP51 inhibits non-small-cell lung cancer by promoting PTEN-mediated EGFR degradation.
He M, Wang X, Chen W, Zhang J, Xiong Y, Cao L, Zhang L, Zhao N, Yang Y, Wang L
Life sciences 2022 May 15;297:120293
Life sciences 2022 May 15;297:120293
Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate autophagy.
Liu N, Zhao H, Zhao YG, Hu J, Zhang H
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
The role of Mfn2 in the structure and function of endoplasmic reticulum-mitochondrial tethering in vivo.
Han S, Zhao F, Hsia J, Ma X, Liu Y, Torres S, Fujioka H, Zhu X
Journal of cell science 2021 Jul 1;134(13)
Journal of cell science 2021 Jul 1;134(13)
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control.
König T, Nolte H, Aaltonen MJ, Tatsuta T, Krols M, Stroh T, Langer T, McBride HM
Nature cell biology 2021 Dec;23(12):1271-1286
Nature cell biology 2021 Dec;23(12):1271-1286
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
A High-Density Human Mitochondrial Proximity Interaction Network.
Antonicka H, Lin ZY, Janer A, Aaltonen MJ, Weraarpachai W, Gingras AC, Shoubridge EA
Cell metabolism 2020 Sep 1;32(3):479-497.e9
Cell metabolism 2020 Sep 1;32(3):479-497.e9
Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation.
Yamanaka T, Nishiyama R, Shimogori T, Nukina N
Scientific reports 2020 May 6;10(1):7610
Scientific reports 2020 May 6;10(1):7610
The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.
Zhao YG, Chen Y, Miao G, Zhao H, Qu W, Li D, Wang Z, Liu N, Li L, Chen S, Liu P, Feng D, Zhang H
Molecular cell 2017 Sep 21;67(6):974-989.e6
Molecular cell 2017 Sep 21;67(6):974-989.e6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 20641-1-AP(PTPIP51 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using FAM82A2 antibody 20641-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 20641-1-AP(PTPIP51 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 20641-1-AP(PTPIP51 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
