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- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 66118-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- FUT8 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated FUT8 antibody (Cat. #66118-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2F7H2
- Vial size
- 20ul, 150ul
Submitted references Core Fucosylation Mediated by the FucT-8 Enzyme Affects TRAIL-Induced Apoptosis and Sensitivity to Chemotherapy in Human SW480 and SW620 Colorectal Cancer Cells.
FUT8 is regulated by miR-122-5p and promotes malignancies in intrahepatic cholangiocarcinoma via PI3K/AKT signaling.
Fucosyltransferase 8 is Overexpressed and Influences Clinical Outcomes in Lung Adenocarcinoma Patients.
Origin of cytoplasmic GDP-fucose determines its contribution to glycosylation reactions.
Inhibition of α(1,6)fucosyltransferase: Effects on Cell Proliferation, Migration, and Adhesion in an SW480/SW620 Syngeneic Colorectal Cancer Model.
Fucosyltransferase 8 modulates receptor tyrosine kinase activation and temozolomide resistance in glioblastoma cells.
Glycan array analysis of Pholiota squarrosa lectin and other fucose-oriented lectins.
Glycomic Profiling Highlights Increased Fucosylation in Pseudomyxoma Peritonei.
Biallelic Mutations in FUT8 Cause a Congenital Disorder of Glycosylation with Defective Fucosylation.
A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis.
Altered fucosyltransferase expression in the superior temporal gyrus of elderly patients with schizophrenia.
López-Cortés R, Correa Pardo I, Muinelo-Romay L, Fernández-Briera A, Gil-Martín E
International journal of molecular sciences 2023 Jul 25;24(15)
International journal of molecular sciences 2023 Jul 25;24(15)
FUT8 is regulated by miR-122-5p and promotes malignancies in intrahepatic cholangiocarcinoma via PI3K/AKT signaling.
Chen F, Li Y, Aye L, Wu Y, Dong L, Yang Z, Gao Q, Zhang S
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):79-91
Cellular oncology (Dordrecht, Netherlands) 2023 Feb;46(1):79-91
Fucosyltransferase 8 is Overexpressed and Influences Clinical Outcomes in Lung Adenocarcinoma Patients.
Liang Y, Wang T, Gao R, Jia X, Ji T, Shi P, Xue J, Yang A, Chen M, Han P
Pathology oncology research : POR 2022;28:1610116
Pathology oncology research : POR 2022;28:1610116
Origin of cytoplasmic GDP-fucose determines its contribution to glycosylation reactions.
Sosicka P, Ng BG, Pepi LE, Shajahan A, Wong M, Scott DA, Matsumoto K, Xia ZJ, Lebrilla CB, Haltiwanger RS, Azadi P, Freeze HH
The Journal of cell biology 2022 Oct 3;221(10)
The Journal of cell biology 2022 Oct 3;221(10)
Inhibition of α(1,6)fucosyltransferase: Effects on Cell Proliferation, Migration, and Adhesion in an SW480/SW620 Syngeneic Colorectal Cancer Model.
López-Cortés R, Muinelo-Romay L, Fernández-Briera A, Gil-Martín E
International journal of molecular sciences 2022 Jul 30;23(15)
International journal of molecular sciences 2022 Jul 30;23(15)
Fucosyltransferase 8 modulates receptor tyrosine kinase activation and temozolomide resistance in glioblastoma cells.
Wei KC, Lin YC, Chen CH, Chu YH, Huang CY, Liao WC, Liu CH
American journal of cancer research 2021;11(11):5472-5484
American journal of cancer research 2021;11(11):5472-5484
Glycan array analysis of Pholiota squarrosa lectin and other fucose-oriented lectins.
Rubén LC, Laura MR, Almudena FB, Emilio GM
Glycobiology 2021 May 3;31(4):459-476
Glycobiology 2021 May 3;31(4):459-476
Glycomic Profiling Highlights Increased Fucosylation in Pseudomyxoma Peritonei.
Saarinen L, Nummela P, Leinonen H, Heiskanen A, Thiel A, Haglund C, Lepistö A, Satomaa T, Hautaniemi S, Ristimäki A
Molecular & cellular proteomics : MCP 2018 Nov;17(11):2107-2118
Molecular & cellular proteomics : MCP 2018 Nov;17(11):2107-2118
Biallelic Mutations in FUT8 Cause a Congenital Disorder of Glycosylation with Defective Fucosylation.
Ng BG, Xu G, Chandy N, Steyermark J, Shinde DN, Radtke K, Raymond K, Lebrilla CB, AlAsmari A, Suchy SF, Powis Z, Faqeih EA, Berry SA, Kronn DF, Freeze HH
American journal of human genetics 2018 Jan 4;102(1):188-195
American journal of human genetics 2018 Jan 4;102(1):188-195
A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis.
Agrawal P, Fontanals-Cirera B, Sokolova E, Jacob S, Vaiana CA, Argibay D, Davalos V, McDermott M, Nayak S, Darvishian F, Castillo M, Ueberheide B, Osman I, Fenyö D, Mahal LK, Hernando E
Cancer cell 2017 Jun 12;31(6):804-819.e7
Cancer cell 2017 Jun 12;31(6):804-819.e7
Altered fucosyltransferase expression in the superior temporal gyrus of elderly patients with schizophrenia.
Mueller TM, Yates SD, Haroutunian V, Meador-Woodruff JH
Schizophrenia research 2017 Apr;182:66-73
Schizophrenia research 2017 Apr;182:66-73
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 66118-1-Ig(FUT8 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FUT8 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human FUT8. This antibody recognizes human antigen. The FUT8 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
